Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State
Cerqueira B, Boas W, Seixas M, Damasceno E, Souza C, Reis M, Goncalves M. Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State. Blood 2008, 112: 2504. DOI: 10.1182/blood.v112.11.2504.2504.Peer-Reviewed Original ResearchVaso-occlusive eventsInflammatory stateVascular occlusionSCA patientsRed blood cellsLeukocyte activationHemolytic stateExpression levelsSickle cell complicationsExpression of CD62LHigher CRP levelsSoluble adhesion moleculesChronic inflammatory stateVenous blood samplesNaïve T lymphocytesHigh endothelial venulesFetal hemoglobinActivation stateCD62L expression levelsCell surface antigensLeukocyte cell surface antigensVascular complicationsCD62L expressionCRP levelsEndothelial dysfunctionClinical and molecular characteristics of sickle cell anemia in the northeast of Brazil
Adorno E, Zanette Â, Lyra I, Seixas M, Reis M, Gonçalves M. Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil. Genetics And Molecular Biology 2008, 31: 621-625. DOI: 10.1590/s1415-47572008000400003.Peer-Reviewed Original ResearchSevere sickle cell anemiaSickle cell anemiaCell anemiaBeta S-globin gene haplotypesMean hemoglobin concentrationLow mean corpuscular volumeMean corpuscular volumeErythrocyte transfusionCerebrovascular accidentHigher mean hemoglobin concentrationHigh HbF levelsClinical dataCAR haplotypeHemoglobin concentrationCorpuscular volumeCorpuscular hemoglobinOutpatientsHbF levelsFetal hemoglobinAnemiaPCR-RFLPCarrier valuesHemoglobinGene haplotypesMolecular characteristics