Role of Oxygen Free Radical in the Expression of Interleukin-8 andInterleukin-1beta Gene in Mononuclear Phagocytic Cells
Kang M, Kim J, Park J, Lee S, Yoo C, Kim Y, Han S, Shim Y. Role of Oxygen Free Radical in the Expression of Interleukin-8 andInterleukin-1beta Gene in Mononuclear Phagocytic Cells. Tuberculosis And Respiratory Diseases 1995, 42: 862-870. DOI: 10.4046/trd.1995.42.6.862.Peer-Reviewed Original ResearchNorthern blot analysisActivation of NFkappaBIntracellular signal transduction pathwaysIL-1beta geneSignal transduction pathwaysBlot analysisMononuclear phagocytic cellsTranscription factor NFkappaBPhagocytic cellsActivation of NFkappaB.Extracellular stimuliTransduction pathwaysCytoplasmic formMild oxidant stressSecondary messengersProtein subunitsDependent expressionGenesCell typesTime-dependent expressionExogenous H2O2MRNA expressionPhorbol esterNFkappaBLPS stimulation