2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2013
Event‐by‐event respiratory motion correction for PET with 3D internal‐1D external motion correlation
Chan C, Jin X, Fung EK, Naganawa M, Mulnix T, Carson RE, Liu C. Event‐by‐event respiratory motion correction for PET with 3D internal‐1D external motion correlation. Medical Physics 2013, 40: 112507. PMID: 24320466, DOI: 10.1118/1.4826165.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungFluorine RadioisotopesHealthy VolunteersHumansHypoxiaImage Processing, Computer-AssistedImaging, Three-DimensionalInsulin-Secreting CellsKidneyLung NeoplasmsMisonidazoleMovementPancreasPositron-Emission TomographyRegression AnalysisReproducibility of ResultsRespirationSignal Processing, Computer-AssistedTetrabenazineX-Ray Microtomography