Featured Publications
Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks
2017
Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder
Scheinost D, Holmes SE, DellaGioia N, Schleifer C, Matuskey D, Abdallah CG, Hampson M, Krystal JH, Anticevic A, Esterlis I. Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder. Neuropsychopharmacology 2017, 43: 1119-1127. PMID: 28944772, PMCID: PMC5854800, DOI: 10.1038/npp.2017.229.Peer-Reviewed Original ResearchConceptsMajor depressive disorderAnterior cingulate cortexIntrinsic functional connectivityMedial prefrontal cortexFunctional connectivityLarge-scale brain networksDepressive disorderMDD groupAnatomical covarianceBrain networksUnmedicated major depressive disorderWhole-brain intrinsic functional connectivitySystem-level disorderIntrinsic connectivity distributionRegional brain structureMultiple brain networksAltered connectivityCommon findingHealthy comparison participantsDepressive symptomsAltered volumeUnmedicated individualsLocal circuitryCingulate cortexDepressive symptomatology