2023
Air Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study
Lee W, Wu X, Heo S, Kim J, Fong K, Son J, Sabath M, Trisovic A, Braun D, Park J, Kim Y, Lee J, Schwartz J, Kim H, Dominici F, Al-Aly Z, Bell M. Air Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study. Environmental Health Perspectives 2023, 131: 047008. PMID: 37036790, PMCID: PMC10084931, DOI: 10.1289/ehp10729.Peer-Reviewed Original ResearchConceptsAcute kidney injuryFirst hospital admissionLongitudinal cohort studyHospital admissionKidney injuryCohort studyHazard ratioPopulation-based longitudinal cohort studyU.S. Medicare populationYears of ageAir pollution exposureNationwide Medicare dataPublic health policyCurrent National Ambient Air Quality StandardHealth care expendituresKidney functionDisease burdenMedicare populationMedicare dataLong-term exposureAdmissionPollution exposureHealth policyCare expendituresEffect estimates
2022
Low temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients
Zhang Q, Peng L, Hu J, Li H, Jiang Y, Fang W, Yan H, Chen J, Wang W, Xiang D, Su X, Yu B, Wang Y, Xu Y, Wang L, Li C, Chen Y, Zhao D, Ge W, Bell M, Gasparrini A, Ge J, Huo Y, Kan H. Low temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients. The Lancet Regional Health - Western Pacific 2022, 28: 100562. PMID: 35991537, PMCID: PMC9386641, DOI: 10.1016/j.lanwpc.2022.100562.Peer-Reviewed Original ResearchAcute aortic dissectionAAD onsetDisease burdenAAD casesLife-threatening cardiovascular emergencyTime-stratified case-crossover studyAortic dissection riskCorresponding disease burdenGreat public health significanceModifiable risk factorsConditional logistic regressionCase-crossover studyLarge nationwide studyCase-crossover analysisMedical Research Council UKPublic health significanceAortic dissectionAssociation of temperatureCardiovascular emergenciesResearch Council UKRisk factorsAttributable fractionExposure-response curvesCumulative relative riskRelative risk
2018
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Kyu H, Abate D, Abate K, Abay S, Abbafati C, Abbasi N, Abbastabar H, Abd-Allah F, Abdela J, Abdelalim A, Abdollahpour I, Abdulkader R, Abebe M, Abebe Z, Abil O, Aboyans V, Abrham A, Abu-Raddad L, Abu-Rmeileh N, Accrombessi M, Acharya D, Acharya P, Ackerman I, Adamu A, Adebayo O, Adekanmbi V, Ademi Z, Adetokunboh O, Adib M, Adsuar J, Afanvi K, Afarideh M, Afshin A, Agarwal G, Agesa K, Aggarwal R, Aghayan S, Agrawal A, Ahmadi A, Ahmadi M, Ahmadieh H, Ahmed M, Ahmed S, Aichour A, Aichour I, Aichour M, Akinyemiju T, Akseer N, Al-Aly Z, Al-Eyadhy A, Al-Mekhlafi H, Al-Raddadi R, Alahdab F, Alam K, Alam T, Alashi A, Alavian S, Alene K, Alijanzadeh M, Alizadeh-Navaei R, Aljunid S, Alkerwi A, Alla F, Allebeck P, Alonso J, Alsharif U, Altirkawi K, Alvis-Guzman N, Aminde L, Amini E, Amiresmaili M, Ammar W, Amoako Y, Anber N, Andrei C, Androudi S, Animut M, Anjomshoa M, Ansha M, Antonio C, Anwari P, Arabloo J, Aremu O, Ärnlöv J, Arora A, Arora M, Artaman A, Aryal K, Asayesh H, Ataro Z, Ausloos M, Avila-Burgos L, Avokpaho E, Awasthi A, Ayala Quintanilla B, Ayer R, Azzopardi P, Babazadeh A, Badali H, Balakrishnan K, Bali A, Banach M, Banoub J, Barac A, Barboza M, Barker-Collo S, Bärnighausen T, Barquera S, Barrero L, Bazargan-Hejazi S, Bedi N, Beghi E, Behzadifar M, Behzadifar M, Bekele B, Bekru E, Belachew A, Belay Y, Bell M, Bello A, Bennett D, Bensenor I, Berhane A, Bernabe E, Bernstein R, Beuran M, Beyranvand T, Bhala N, Bhatt S, Bhaumik S, Bhutta Z, Biadgo B, Biehl M, Bijani A, Bikbov B, Bilano V, Bililign N, Bin Sayeed M, Bisanzio D, Bjørge T, Bleyer A, Bobasa E, Bou-Orm I, Boufous S, Bourne R, Brady O, Brant L, Brayne C, Brazinova A, Breitborde N, Brenner H, Briant P, Briko A, Britton G, Brugha T, Buchbinder R, Busse R, Butt Z, Cahuana-Hurtado L, Campuzano Rincon J, Cano J, Cárdenas R, Carrero J, Carter A, Carvalho F, Castañeda-Orjuela C, Castillo Rivas J, Castro F, Catalá-López F, Cercy K, Cerin E, Chaiah Y, Chang J, Charlson F, Chattu V, Chiang P, Chitheer A, Choi J, Christensen H, Christopher D, Chung S, Cicuttini F, Cirillo M, Collado-Mateo D, Cooper C, Cortesi P, Cortinovis M, Cousin E, Criqui M, Cromwell E, Cross M, Crump J, Daba A, Dachew B, Dadi A, Dandona L, Dandona R, Dargan P, Daryani A, Das Gupta R, Das Neves J, Dasa T, Davitoiu D, De La Hoz F, De Leo D, De Neve J, De Steur H, Degefa M, Degenhardt L, Deiparine S, Demoz G, Denova-Gutiérrez E, Deribe K, Dervenis N, Des Jarlais D, Dey S, Dharmaratne S, Dhimal M, Dinberu M, Dirac M, Djalalinia S, Doan L, Dokova K, Doku D, Dorsey E, Doyle K, Driscoll T, Dubey M, Dubljanin E, Duken E, Duncan B, Duraes A, Ebrahimi H, Ebrahimpour S, Echko M, Edessa D, Edvardsson D, Effiong A, Eggen A, Ehrlich J, El Bcheraoui C, El-Khatib Z, Elyazar I, Enayati A, Endalifer M, Endries A, Er B, Erskine H, Eskandarieh S, Esteghamati A, Esteghamati S, Fakhim H, Faramarzi M, Fareed M, Farhadi F, Farid T, Farinha C, Farioli A, Faro A, Farzadfar F, Fazaeli A, Feigin V, Fentahun N, Fereshtehnejad S, Fernandes E, Fernandes J, Ferrari A, Ferreira M, Filip I, Fischer F, Fitzmaurice C, Foigt N, Foreman K, Frank T, Fukumoto T, Fullman N, Fürst T, Furtado J, Gakidou E, Gall S, Gallus S, Ganji M, Garcia-Basteiro A, Gardner W, Gebre A, Gebremedhin A, Gebremichael T, Gelano T, Geleijnse J, Genova-Maleras R, Geramo Y, Gething P, Gezae K, Ghadami M, Ghadiri K, Ghasemi-Kasman M, Ghimire M, Ghoshal A, Gill P, Gill T, Ginawi I, Giussani G, Gnedovskaya E, Goldberg E, Goli S, Gómez-Dantés H, Gona P, Gopalani S, Gorman T, Goulart A, Goulart B, Grada A, Grosso G, Gugnani H, Guillemin F, Guo Y, Gupta P, Gupta R, Gupta R, Gupta T, Gutiérrez R, Gyawali B, Haagsma J, Hachinski V, Hafezi-Nejad N, Haghparast Bidgoli H, Hagos T, Hailegiyorgis T, Haj-Mirzaian A, Haj-Mirzaian A, Hamadeh R, Hamidi S, Handal A, Hankey G, Hao Y, Harb H, Harikrishnan S, Haririan H, Haro J, Hassankhani H, Hassen H, Havmoeller R, Hay R, Hay S, Hedayatizadeh-Omran A, Heibati B, Hendrie D, Henok A, Heredia-Pi I, Herteliu C, Heydarpour F, Heydarpour P, Hibstu D, Hoek H, Hoffman H, Hole M, Homaie Rad E, Hoogar P, Hosgood H, Hosseini S, Hosseinzadeh M, Hostiuc M, Hostiuc S, Hotez P, Hoy D, Hsairi M, Htet A, Huang J, Iburg K, Ikeda C, Ilesanmi O, Irvani S, Irvine C, Islam S, Islami F, Jacobsen K, Jahangiry L, Jahanmehr N, Jain S, Jakovljevic M, James S, Jayatilleke A, Jeemon P, Jha R, Jha V, Ji J, Johnson C, Jonas J, Jonnagaddala J, Jorjoran Shushtari Z, Joshi A, Jozwiak J, Jungari S, Jürisson M, Kabir Z, Kadel R, Kahsay A, Kalani R, Kanchan T, Kar C, Karami M, Karami Matin B, Karch A, Karema C, Karimi N, Karimi S, Kasaeian A, Kassa D, Kassa G, Kassa T, Kassebaum N, Katikireddi S, Kaul A, Kawakami N, Kazemi Z, Karyani A, Keighobadi M, Keiyoro P, Kemmer L, Kemp G, Kengne A, Keren A, Khader Y, Khafaei B, Khafaie M, Khajavi A, Khalid N, Khalil I, Khan E, Khan M, Khan M, Khang Y, Khater M, Khazaei M, Khoja A, Khosravi A, Khosravi M, Kiadaliri A, Kidanemariam Z, Kiirithio D, Kim C, Kim D, Kim Y, Kim Y, Kimokoti R, Kinfu Y, Kisa A, Kissimova-Skarbek K, Knudsen A, Kocarnik J, Kochhar S, Kokubo Y, Kolola T, Kopec J, Kosen S, Kotsakis G, Koul P, Koyanagi A, Krishan K, Krishnaswami S, Krohn K, Kuate Defo B, Kucuk Bicer B, Kumar G, Kumar M, Kuzin I, Lad D, Lad S, Lafranconi A, Lalloo R, Lallukka T, Lami F, Lang J, Langan S, Lansingh V, Latifi A, Lau K, Lazarus J, Leasher J, Ledesma J, Lee P, Leigh J, Leili M, Leshargie C, Leung J, Levi M, Lewycka S, Li S, Li Y, Liang X, Liao Y, Liben M, Lim L, Lim S, Limenih M, Linn S, Liu S, Looker K, Lopez A, Lorkowski S, Lotufo P, Lozano R, Lucas T, Lunevicius R, Lyons R, Ma S, Macarayan E, Mackay M, Maddison E, Madotto F, Maghavani D, Mai H, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malta D, Mamun A, Manda A, Manguerra H, Mansournia M, Mantilla Herrera A, Mantovani L, Maravilla J, Marcenes W, Marks A, Martins-Melo F, Martopullo I, März W, Marzan M, Massano J, Massenburg B, Mathur M, Maulik P, Mazidi M, McAlinden C, McGrath J, McKee M, McMahon B, Mehata S, Mehrotra R, Mehta K, Mehta V, Mejia-Rodriguez F, Mekonen T, Melese A, Melku M, Memiah P, Memish Z, Mendoza W, Mengistu G, Mensah G, Mereta S, Meretoja A, Meretoja T, Mestrovic T, Miazgowski B, Miazgowski T, Millear A, Miller T, Mini G, Mirarefin M, Mirica A, Mirrakhimov E, Misganaw A, Mitchell P, Mitiku H, Moazen B, Mohajer B, Mohammad K, Mohammadi M, Mohammadifard N, Mohammadnia-Afrouzi M, Mohammed M, Mohammed S, Mohebi F, Mokdad A, Molokhia M, Monasta L, Montañez J, Moosazadeh M, Moradi G, Moradi M, Moradi-Lakeh M, Moradinazar M, Moraga P, Morawska L, Moreno Velásquez I, Morgado-Da-Costa J, Morrison S, Moschos M, Mousavi S, Mruts K, Muche A, Muchie K, Mueller U, Muhammed O, Mukhopadhyay S, Muller K, Mumford J, Murthy G, Musa K, Mustafa G, Nabhan A, Nagata C, Nagel G, Naghavi M, Naheed A, Nahvijou A, Naik G, Najafi F, Nam H, Nangia V, Nansseu J, Neamati N, Negoi I, Negoi R, Neupane S, Newton C, Ngunjiri J, Nguyen A, Nguyen G, Nguyen H, Nguyen H, Nguyen H, Nguyen L, Nguyen M, Nguyen N, Nguyen S, Nichols E, Ningrum D, Nixon M, Nomura S, Noroozi M, Norrving B, Noubiap J, Nouri H, Shiadeh M, Nowroozi M, Nsoesie E, Nyasulu P, Odell C, Ofori-Asenso R, Ogbo F, Oh I, Oladimeji O, Olagunju A, Olagunju T, Olivares P, Olsen H, Olusanya B, Olusanya J, Ong K, Ong S, Oren E, Ortiz A, Ota E, Otstavnov S, Øverland S, Owolabi M, P A M, Pacella R, Pakhare A, Pakpour A, Pana A, Panda-Jonas S, Park E, Park J, Parry C, Parsian H, Pasdar Y, Patel S, Patil S, Patle A, Patton G, Paturi V, Paudel D, Paulson K, Pearce N, Pereira A, Pereira D, Perico N, Pesudovs K, Petzold M, Pham H, Phillips M, Pigott D, Pillay J, Piradov M, Pirsaheb M, Pishgar F, Plana-Ripoll O, Polinder S, Popova S, Postma M, Pourshams A, Poustchi H, Prabhakaran D, Prakash S, Prakash V, Prasad N, Purcell C, Qorbani M, Quistberg D, Radfar A, Rafay A, Rafiei A, Rahim F, Rahimi K, Rahimi Z, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman M, Rahman S, Rai R, Rajati F, Ranjan P, Rao P, Rasella D, Rawaf D, Rawaf S, Reddy K, Reiner R, Reitsma M, Remuzzi G, Renzaho A, Resnikoff S, Rezaei S, Rezai M, Ribeiro A, Roberts N, Robinson S, Roever L, Ronfani L, Roshandel G, Rostami A, Roth G, Rothenbacher D, Rubagotti E, Sachdev P, Sadat N, Sadeghi E, Saeedi Moghaddam S, Safari H, Safari Y, Safari-Faramani R, Safdarian M, Safi S, Safiri S, Sagar R, Sahebkar A, Sahraian M, Sajadi H, Salam N, Salama J, Salamati P, Saleem Z, Salimi Y, Salimzadeh H, Salomon J, Salvi S, Salz I, Samy A, Sanabria J, Sanchez-Niño M, Santomauro D, Santos I, Santos J, Santric Milicevic M, Sao Jose B, Sardana M, Sarker A, Sarmiento-Suárez R, Sarrafzadegan N, Sartorius B, Sarvi S, Sathian B, Satpathy M, Sawant A, Sawhney M, Saxena S, Schaeffner E, Schmidt M, Schneider I, Schutte A, Schwebel D, Schwendicke F, Scott J, Sekerija M, Sepanlou S, Serván-Mori E, Seyedmousavi S, Shabaninejad H, Shafieesabet A, Shahbazi M, Shaheen A, Shaikh M, Shams-Beyranvand M, Shamsi M, Sharafi H, Sharafi K, Sharif M, Sharif-Alhoseini M, Sharma J, Sharma R, She J, Sheikh A, Shi P, Shibuya K, Shiferaw M, Shigematsu M, Shiri R, Shirkoohi R, Shiue I, Shokoohinia Y, Shokraneh F, Shoman H, Shrime M, Si S, Siabani S, Sibai A, Siddiqi T, Sigfusdottir I, Sigurvinsdottir R, Silva D, Silva J, Silveira D, Singam N, Singh J, Singh N, Singh V, Sinha D, Skiadaresi E, Skirbekk V, Sliwa K, Smith D, Smith M, Soares Filho A, Sobaih B, Sobhani S, Soofi M, Sorensen R, Soriano J, Soyiri I, Sposato L, Sreeramareddy C, Srinivasan V, Stanaway J, Starodubov V, Stein D, Steiner C, Steiner T, Stokes M, Stovner L, Subart M, Sudaryanto A, Sufiyan M, Sulo G, Sunguya B, Sur P, Sykes B, Sylaja P, Sylte D, Szoeke C, Tabarés-Seisdedos R, Tabuchi T, Tadakamadla S, Tandon N, Tassew S, Tavakkoli M, Taveira N, Taylor H, Tehrani-Banihashemi A, Tekalign T, Tekelemedhin S, Tekle M, Temsah M, Temsah O, Terkawi A, Tessema B, Teweldemedhin M, Thankappan K, Theis A, Thirunavukkarasu S, Thomas N, Tilahun B, To Q, Tonelli M, Topor-Madry R, Torre A, Tortajada-Girbés M, Touvier M, Tovani-Palone M, Towbin J, Tran B, Tran K, Troeger C, Tsadik A, Tsoi D, Tudor Car L, Tyrovolas S, Ukwaja K, Ullah I, Undurraga E, Updike R, Usman M, Uthman O, Vaduganathan M, Vaezi A, Valdez P, Varavikova E, Varughese S, Vasankari T, Venketasubramanian N, Villafaina S, Violante F, Vladimirov S, Vlassov V, Vollset S, Vos T, Vosoughi K, Vujcic I, Wagnew F, Waheed Y, Wang Y, Wang Y, Weiderpass E, Weintraub R, Weiss D, Weldegebreal F, Weldegwergs K, Werdecker A, West T, Westerman R, Whiteford H, Widecka J, Wijeratne T, Williams H, Wilner L, Wilson S, Winkler A, Wiyeh A, Wiysonge C, Wolfe C, Woolf A, Wyper G, Xavier D, Xu G, Yadgir S, Yahyazadeh Jabbari S, Yamada T, Yan L, Yano Y, Yaseri M, Yasin Y, Yeshaneh A, Yimer E, Yip P, Yisma E, Yonemoto N, Yoon S, Yotebieng M, Younis M, Yousefifard M, Yu C, Zadnik V, Zaidi Z, Zaman S, Zamani M, Zandian H, Zar H, Zenebe Z, Zhou M, Zipkin B, Zodpey S, Zucker I, Zuhlke L, Murray C. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet 2018, 392: 1859-1922. PMID: 30415748, PMCID: PMC6252083, DOI: 10.1016/s0140-6736(18)32335-3.Peer-Reviewed Original ResearchConceptsHigh SDI countriesLow SDI countriesAge-standardised DALY ratesYears of lifeHealthy life expectancySDI countriesNon-communicable diseasesSocio-demographic IndexNeonatal disordersPoor healthAge-specific mortality ratesDALY ratesLife expectancyDisease burdenGood healthGlobal burdenPremature mortalityMortality rateCommunicable diseasesRisk Factors Study (GBD) 2017Chronic obstructive pulmonary diseaseCauses of DALYsSum of YLLsAdditional yearLower respiratory infections
2017
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Collaborators G, Hay S, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abdulkader R, Abdulle A, Abebo T, Abera S, Aboyans V, Abu-Raddad L, Ackerman I, Adedeji I, Adetokunboh O, Afshin A, Aggarwal R, Agrawal S, Agrawal A, Ahmed M, Aichour M, Aichour A, Aichour I, Aiyar S, Akinyemiju T, Akseer N, Al Lami F, Alahdab F, Al-Aly Z, Alam K, Alam N, Alam T, Alasfoor D, Alene K, Ali R, Alizadeh-Navaei R, Alkaabi J, Alkerwi A, Alla F, Allebeck P, Allen C, Al-Maskari F, AlMazroa M, Al-Raddadi R, Alsharif U, Alsowaidi S, Althouse B, Altirkawi K, Alvis-Guzman N, Amare A, Amini E, Ammar W, Amoako Y, Ansha M, Antonio C, Anwari P, Ärnlöv J, Arora M, Artaman A, Aryal K, Asgedom S, Atey T, Atnafu N, Avila-Burgos L, Avokpaho E, Awasthi A, Awasthi S, Azarpazhooh M, Azzopardi P, Babalola T, Bacha U, Badawi A, Balakrishnan K, Bannick M, Barac A, Barker-Collo S, Bärnighausen T, Barquera S, Barrero L, Basu S, Battista R, Battle K, Baune B, Bazargan-Hejazi S, Beardsley J, Bedi N, Béjot Y, Bekele B, Bell M, Bennett D, Bennett J, Bensenor I, Benson J, Berhane A, Berhe D, Bernabé E, Betsu B, Beuran M, Beyene A, Bhansali A, Bhatt S, Bhutta Z, Biadgilign S, Bicer B, Bienhoff K, Bikbov B, Birungi C, Biryukov S, Bisanzio D, Bizuayehu H, Blyth F, Boneya D, Bose D, Bou-Orm I, Bourne R, Brainin M, Brayne C, Brazinova A, Breitborde N, Briant P, Britton G, Brugha T, Buchbinder R, Bulto L, Bumgarner B, Butt Z, Cahuana-Hurtado L, Cameron E, Campos-Nonato I, Carabin H, Cárdenas R, Carpenter D, Carrero J, Carter A, Carvalho F, Casey D, Castañeda-Orjuela C, Castle C, Catalá-López F, Chang J, Charlson F, Chaturvedi P, Chen H, Chibalabala M, Chibueze C, Chisumpa V, Chitheer A, Chowdhury R, Christopher D, Ciobanu L, Cirillo M, Colombara D, Cooper L, Cooper C, Cortesi P, Cortinovis M, Criqui M, Cromwell E, Cross M, Crump J, Dadi A, Dalal K, Damasceno A, Dandona L, Dandona R, Neves J, Davitoiu D, Davletov K, de Courten B, De Leo D, De Steur H, Defo B, Degenhardt L, Deiparine S, Dellavalle R, Deribe K, Deribew A, Jarlais D, Dey S, Dharmaratne S, Dhillon P, Dicker D, Djalainia S, Phuc H, Dokova K, Doku D, Dorsey E, dos Santos K, Driscoll T, Dubey M, Duncan B, Ebel B, Echko M, El-Khatib Z, Enayati A, Endries A, Ermakov S, Erskine H, Eshetie S, Eshrati B, Esteghamati A, Estep K, Fanuel F, Farag T, Farinha C, Faro A, Farzadfar F, Fazeli M, Feigin V, Feigl A, Fereshtehnejad S, Fernandes J, Ferrari A, Feyissa T, Filip I, Fischer F, Fitzmaurice C, Flaxman A, Foigt N, Foreman K, Franklin R, Frostad J, Fullman N, Fürst T, Furtado J, Futran N, Gakidou E, Garcia-Basteiro A, Gebre T, Gebregergs G, Gebrehiwot T, Geleijnse J, Geleto A, Gemechu B, Gesesew H, Gething P, Ghajar A, Gibney K, Gillum R, Ginawi I, Gishu M, Giussani G, Godwin W, Goel K, Goenka S, Goldberg E, Gona P, Goodridge A, Gopalani S, Gosselin R, Gotay C, Goto A, Goulart A, Graetz N, Gugnani H, Gupta P, Gupta R, Gupta T, Gupta V, Gupta R, Gutiérrez R, Hachinski V, Hafezi-Nejad N, Hailu A, Hailu G, Hamadeh R, Hamidi S, Hammami M, Handal A, Hankey G, Hao Y, Harb H, Hareri H, Haro J, Harun K, Harvey J, Hassanvand M, Havmoeller R, Hay R, Hedayati M, Hendrie D, Henry N, Heredia-Pi I, Heydarpour P, Hoek H, Hoffman H, Horino M, Horita N, Hosgood H, Hostiuc S, Hotez P, Hoy D, Htet A, Hu G, Huang J, Huynh C, Iburg K, Igumbor E, Ikeda C, Irvine C, Islam M, Jacobsen K, Jahanmehr N, Jakovljevic M, James P, Jassal S, Javanbakht M, Jayaraman S, Jeemon P, Jensen P, Jha V, Jiang G, John D, Johnson C, Johnson S, Jonas J, Jürisson M, Kabir Z, Kadel R, Kahsay A, Kamal R, Kar C, Karam N, Karch A, Karema C, Karimi S, Karimkhani C, Kasaeian A, Kassa G, Kassaw N, Kassebaum N, Kastor A, Katikireddi S, Kaul A, Kawakami N, Keiyoro P, Kemmer L, Kengne A, Keren A, Kesavachandran C, Khader Y, Khalil I, Khan E, Khang Y, Khoja A, Khosravi A, Khubchandani J, Kiadaliri A, Kieling C, Kim Y, Kim D, Kimokoti R, Kinfu Y, Kisa A, Kissimova-Skarbek K, Kissoon N, Kivimaki M, Knudsen A, Kokubo Y, Kolte D, Kopec J, Kosen S, Kotsakis G, Koul P, Koyanagi A, Kravchenko M, Krohn K, Kumar G, Kumar P, Kyu H, Lager A, Lal D, Lalloo R, Lallukka T, Lambert N, Lan Q, Lansingh V, Larsson A, Leasher J, Lee P, Leigh J, Leshargie C, Leung J, Leung R, Levi M, Li Y, Li Y, Liang X, Liben M, Lim S, Linn S, Liu P, Liu A, Liu S, Liu Y, Lodha R, Logroscino G, Looker K, Lopez A, Lorkowski S, Lotufo P, Lozano R, Lucas T, Lunevicius R, Lyons R, Macarayan E, Maddison E, Razek H, Razek M, Magis-Rodriguez C, Mahdavi, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malhotra R, Malta D, Mamun A, Manguerra H, Manhertz T, Mantovani L, Mapoma C, March L, Marczak L, Martinez-Raga J, Martins P, Martins-Melo F, Martopullo I, März W, Mathur M, Mazidi M, McAlinden C, McGaughey M, McGrath J, McKee M, Mehata S, Meier T, Meles K, Memiah P, Memish Z, Mendoza W, Mengesha M, Mengistie M, Mengistu D, Mensah G, Meretoja T, Meretoja A, Mezgebe H, Micha R, Millear A, Miller T, Minnig S, Mirarefin M, Mirrakhimov E, Misganaw A, Mishra S, Mitchell P, Mohammad K, Mohammadi A, Mohammed M, Mohammed K, Mohammed S, Mohan M, Mokdad A, Mollenkopf S, Monasta L, Hernandez J, Montico M, Moradi-Lakeh M, Moraga P, Morawska L, Mori R, Morrison S, Moses M, Mountjoy-Venning C, Mruts K, Mueller U, Muller K, Murdoch M, Murthy G, Murthy S, Musa K, Nachega J, Nagel G, Naghavi M, Naheed A, Naidoo K, Nangia V, Nasher J, Natarajan G, Negasa D, Negoi R, Negoi I, Newton C, Ngunjiri J, Nguyen C, Le Nguyen Q, Nguyen T, Nguyen G, Nguyen M, Nichols E, Ningrum D, Nong V, Norheim O, Norrving B, Noubiap J, Nyandwi A, Obermeyer C, O'Donnell M, Ogbo F, Oh I, Okoro A, Oladimeji O, Olagunju A, Olagunju T, Olsen H, Olusanya B, Olusanya J, Ong K, Opio J, Oren E, Ortiz A, Osborne R, Osgood-Zimmerman A, Osman M, Ota E, Owolabi M, Mahesh P, Pacella R, Panda B, Pandian J, Papachristou C, Park E, Parry C, Parsaeian M, Patil S, Patten S, Patton G, Paudel D, Paulson K, Pearce N, Pereira D, Perez K, Perico N, Pesudovs K, Peterson C, Petri W, Petzold M, Phillips M, Phipps G, Pigott D, Pillay J, Pinho C, Piradov M, Plass D, Pletcher M, Popova S, Poulton R, Pourmalek F, Prabhakaran D, Prasad N, Purcell C, Purwar M, Qorbani M, Quintanilla B, Rabiee R, Radfar A, Rafay A, Rahimi K, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman M, Kumar R, Rajsic S, Ram U, Ranabhat C, Rangaswamy T, Rankin Z, Rao P, Rao P, Rawaf S, Ray S, Reiner R, Reinig N, Reitsma M, Remuzzi G, Renzaho A, Resnikoff S, Rezaei S, Ribeiro A, Rivas J, Roba H, Robinson S, Rojas-Rueda D, Rokni M, Ronfani L, Roshandel G, Roth G, Rothenbacher D, Roy A, Rubagotti E, Ruhago G, Saadat S, Safdarian, Safiri S, Sagar R, Sahathevan R, Sahraian M, Salama J, Saleh M, Salomon J, Salvi S, Samy A, Sanabria J, Sanchez-Niño M, Santomauro D, Santos J, Santos I, Milicevic M, Sartorius B, Satpathy M, Sawhney M, Saxena S, Schelonka K, Schmidt M, Schneider I, Schöttker B, Schutte A, Schwebel D, Schwendicke F, Seedat S, Sepanlou S, Servan-Mori E, Shaheen A, Shaikh M, Shamsipour M, Sharma R, Sharma J, She J, Shi P, Shibuya K, Shields C, Shifa G, Shiferaw M, Shigematsu M, Shiri R, Shirkoohi R, Shirude S, Shishani K, Shoman H, Siabani S, Sibai A, Sigfusdottir I, Silberberg D, Silva D, Silva J, Silveira D, Singh J, Singh O, Singh N, Singh V, Sinha D, Skiadaresi E, Slepak E, Smith D, Smith M, Sobaih B, Sobngwi E, Soljak M, Sorensen R, Sousa T, Sposato L, Sreeramareddy C, Srinivasan V, Stanaway J, Stathopoulou V, Steel N, Stein D, Steiner C, Steinke S, Stokes M, Stovner L, Strub B, Subart M, Sufiyan M, Sunguya B, Sur P, Swaminathan S, Sykes B, Sylte D, Szoeke C, Tabarés-Seisdedos R, Tadakamadla S, Taffere G, Takala J, Tandon N, Tanne D, Tarekegn Y, Tavakkoli M, Taveira N, Taylor H, Tegegne T, Tehrani-Banihashemi A, Tekelab T, Terkawi A, Tesfaye D, Tesssema B, Thakur J, Thamsuwan O, Theadom A, Theis A, Thomas K, Thomas N, Thompson R, Thrift A, Tobe-Gai R, Tobollik M, Tonelli M, Topor-Madry R, Tortajada M, Touvier M, Traebert J, Tran B, Troeger C, Truelsen T, Tsoi D, Tuzcu E, Tymeson H, Tyrovolas S, Ukwaja K, Undurraga E, Uneke C, Updike R, Uthman O, Uzochukwu B, van Boven J, Varughese S, Vasankari T, Veerman L, Venkatesh S, Venketasubramanian N, Vidavalur R, Vijayakumar L, Violante F, Vishnu A, Vladimirov S, Vlassov V, Vollset S, Vos T, Wadilo F, Wakayo T, Wallin M, Wang Y, Weichenthal S, Weiderpass E, Weintraub R, Weiss D, Werdecker A, Westerman R, Whiteford H, Wijeratne T, Williams H, Wiysonge C, Woldeyes B, Wolfe C, Woodbrook R, Woolf A, Workicho A, Xavier D, Xu G, Yadgir S, Yaghoubi M, Yakob B, Yan L, Yano Y, Ye P, Yihdego M, Yimam H, Yip P, Yonemoto N, Yoon S, Yotebieng M, Younis M, Yu C, Zaidi Z, Zaki M, Zegeye E, Zenebe Z, Zhang X, Zheng Y, Zhou M, Zipkin B, Zodpey S, Zoeckler L, Zuhlke L, Murray C. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet 2017, 390: 1260-1344. PMID: 28919118, PMCID: PMC5605707, DOI: 10.1016/s0140-6736(17)32130-x.Peer-Reviewed Original ResearchConceptsAge-standardised DALY ratesSocio-demographic IndexNon-communicable diseasesHealthy life expectancyYears of lifeDALY ratesGlobal burdenDisease burdenNon-fatal disease burdenRisk Factors Study 2016Causes of DALYsIschemic heart diseaseDisease Study 2016Age 65 yearsLife expectancyCause-specific mortalityMost non-communicable diseasesAge 15 yearsHealth system performanceAge-specific death ratesCause mortalityRespiratory infectionsCerebrovascular diseaseDALY burdenGlobal DALYs
2016
Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Kassebaum N, Arora M, Barber R, Bhutta Z, Brown J, Carter A, Casey D, Charlson F, Coates M, Coggeshall M, Cornaby L, Dandona L, Dicker D, Erskine H, Ferrari A, Fitzmaurice C, Foreman K, Forouzanfar M, Fullman N, Gething P, Goldberg E, Graetz N, Haagsma J, Hay S, Johnson C, Kemmer L, Khalil I, Kinfu Y, Kutz M, Kyu H, Leung J, Liang X, Lim S, Lozano R, Mensah G, Mikesell J, Mokdad A, Mooney M, Naghavi M, Nguyen G, Nsoesie E, Pigott D, Pinho C, Rankin Z, Reinig N, Salomon J, Sandar L, Smith A, Sorensen R, Stanaway J, Steiner C, Teeple S, Troeger C, Truelsen T, VanderZanden A, Wagner J, Wanga V, Whiteford H, Zhou M, Zoeckler L, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abraham B, Abubakar I, Abu-Raddad L, Abu-Rmeileh N, Achoki T, Ackerman I, Adebiyi A, Adedeji I, Adsuar J, Afanvi K, Afshin A, Agardh E, Agarwal A, Agarwal S, Ahmed M, Kiadaliri A, Ahmadieh H, Akseer N, Al-Aly Z, Alam K, Alam N, Aldhahri S, Alegretti M, Aleman A, Alemu Z, Alexander L, Ali R, Alkerwi A, Alla F, Allebeck P, Allen C, Alsharif U, Altirkawi K, Martin E, Alvis-Guzman N, Amare A, Amberbir A, Amegah A, Amini H, Ammar W, Amrock S, Anderson G, Anderson B, Antonio C, Anwari P, Ärnlöv J, Arsenijevic V, Artaman A, Asayesh H, Asghar R, Avokpaho E, Awasthi A, Quintanilla B, Azzopardi P, Bacha U, Badawi A, Balakrishnan K, Banerjee A, Barac A, Barker-Collo S, Bärnighausen T, Barregard L, Barrero L, Basu S, Bayou T, Beardsley J, Bedi N, Beghi E, Bell B, Bell M, Benjet C, Bennett D, Bensenor I, Berhane A, Bernabé E, Betsu B, Beyene A, Bhala N, Bhansali A, Bhatt S, Biadgilign S, Bienhoff K, Bikbov B, Abdulhak A, Biryukov S, Bisanzio D, Bjertness E, Blore J, Borschmann R, Boufous S, Bourne R, Brainin M, Brazinova A, Breitborde N, Brugha T, Buchbinder R, Buckle G, Butt Z, Calabria B, Campos-Nonato I, Campuzano J, Carabin H, Carapetis J, Cárdenas R, Carrero J, Castañeda-Orjuela C, Rivas J, Catalá-López F, Cavalleri F, Chang J, Chiang P, Chibalabala M, Chibueze C, Chisumpa V, Choi J, Choudhury L, Christensen H, Ciobanu L, Colistro V, Colomar M, Colquhoun S, Cortinovis M, Crump J, Damasceno A, Dandona R, Dargan P, das Neves J, Davey G, Davis A, Leo D, Degenhardt L, Gobbo L, Derrett S, Jarlais D, deVeber G, Dharmaratne S, Dhillon P, Ding E, Doyle K, Driscoll T, Duan L, Dubey M, Duncan B, Ebrahimi H, Ellenbogen R, Elyazar I, Endries A, Ermakov S, Eshrati B, Esteghamati A, Estep K, Fahimi S, Farid T, Farinha C, Faro A, Farvid M, Farzadfar F, Feigin V, Fereshtehnejad S, Fernandes J, Fernandes J, Fischer F, Fitchett J, Foigt N, Fowkes F, Franklin R, Friedman J, Frostad J, Fürst T, Futran N, Gabbe B, Gankpé F, Garcia-Basteiro A, Gebrehiwot T, Gebremedhin A, Geleijnse J, Gibney K, Gillum R, Ginawi I, Giref A, Giroud M, Gishu M, Giussani G, Godwin W, Gomez-Dantes H, Gona P, Goodridge A, Gopalani S, Gotay C, Goto A, Gouda H, Gugnani H, Guo Y, Gupta R, Gupta R, Gupta V, Gutiérrez R, Hafezi-Nejad N, Haile D, Hailu A, Hailu G, Halasa Y, Hamadeh R, Hamidi S, Hammami M, Handal A, Hankey G, Harb H, Harikrishnan S, Haro J, Hassanvand M, Hassen T, Havmoeller R, Hay R, Hedayati M, Heredia-Pi I, Heydarpour P, Hoek H, Hoffman D, Horino M, Horita N, Hosgood H, Hoy D, Hsairi M, Huang H, Huang J, Iburg K, Idrisov B, Innos K, Inoue M, Jacobsen K, Jauregui A, Jayatilleke A, Jeemon P, Jha V, Jiang G, Jiang Y, Jibat T, Jimenez-Corona A, Jin Y, Jonas J, Kabir Z, Kajungu D, Kalkonde Y, Kamal R, Kan H, Kandel A, Karch A, Karema C, Karimkhani C, Kasaeian A, Katibeh M, Kaul A, Kawakami N, Kazi D, Keiyoro P, Kemp A, Kengne A, Keren A, Kesavachandran C, Khader Y, Khan A, Khan E, Khang Y, Khoja T, Khubchandani J, Kieling C, Kim C, Kim D, Kim Y, Kissoon N, Kivipelto M, Knibbs L, Knudsen A, Kokubo Y, Kolte D, Kopec J, Koul P, Koyanagi A, Defo B, Kuchenbecker R, Bicer B, Kuipers E, Kumar G, Kwan G, Lalloo R, Lallukka T, Larsson A, Latif A, Lavados P, Lawrynowicz A, Leasher J, Leigh J, Leung R, Li Y, Li Y, Lipshultz S, Liu P, Liu Y, Lloyd B, Logroscino G, Looker K, Lotufo P, Lucas R, Lunevicius R, Lyons R, Razek H, Mahdavi M, Majdan M, Majeed A, Malekzadeh R, Malta D, Marcenes W, Martinez-Raga J, Masiye F, Mason-Jones A, Matzopoulos R, Mayosi B, McGrath J, McKee M, Meaney P, Mehari A, Melaku Y, Memiah P, Memish Z, Mendoza W, Meretoja A, Meretoja T, Mesfin Y, Mhimbira F, Millear A, Miller T, Mills E, Mirarefin M, Mirrakhimov E, Mitchell P, Mock C, Mohammad K, Mohammadi A, Mohammed S, Monasta L, Hernandez J, Montico M, Moradi-Lakeh M, Mori R, Mueller U, Mumford J, Murdoch M, Murthy G, Nachega J, Naheed A, Naldi L, Nangia V, Newton J, Ng M, Ngalesoni F, Nguyen Q, Nisar M, Pete P, Nolla J, Norheim O, Norman R, Norrving B, Obermeyer C, Ogbo F, Oh I, Oladimeji O, Olivares P, Olusanya B, Olusanya J, Oren E, Ortiz A, Ota E, Oyekale A, PA M, Park E, Parsaeian M, Patten S, Patton G, Pedro J, Pereira D, Perico N, Pesudovs K, Petzold M, Phillips M, Piel F, Pillay J, Pishgar F, Plass D, Polinder S, Popova S, Poulton R, Pourmalek F, Prasad N, Qorbani M, Rabiee R, Radfar A, Rafay A, Rahimi K, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman S, Rai D, Rai R, Rajsic S, Raju M, Ram U, Ranganathan K, Refaat A, Reitsma M, Remuzzi G, Resnikoff S, Reynolds A, Ribeiro A, Ricci S, Roba H, Rojas-Rueda D, Ronfani L, Roshandel G, Roth G, Roy A, Sackey B, Sagar R, Sanabria J, Sanchez-Niño M, Santos I, Santos J, Sarmiento-Suarez R, Sartorius B, Satpathy M, Savic M, Sawhney M, Schmidt M, Schneider I, Schutte A, Schwebel D, Seedat S, Sepanlou S, Servan-Mori E, Shahraz S, Shaikh M, Sharma R, She J, Sheikhbahaei S, Shen J, Sheth K, Shibuya K, Shigematsu M, Shin M, Shiri R, Sigfusdottir I, Silva D, Silverberg J, Simard E, Singh A, Singh J, Singh P, Skirbekk V, Skogen J, Soljak M, Søreide K, Sorensen R, Sreeramareddy C, Stathopoulou V, Steel N, Stein D, Stein M, Steiner T, Stovner L, Stranges S, Stroumpoulis K, Sunguya B, Sur P, Swaminathan S, Sykes B, Szoeke C, Tabarés-Seisdedos R, Tandon N, Tanne D, Tavakkoli M, Taye B, Taylor H, Ao B, Tegegne T, Tekle D, Terkawi A, Tessema G, Thakur J, Thomson A, Thorne-Lyman A, Thrift A, Thurston G, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tran B, Truelsen T, Dimbuene Z, Tsilimbaris M, Tura A, Tuzcu E, Tyrovolas S, Ukwaja K, Undurraga E, Uneke C, Uthman O, van Gool C, van Os J, Vasankari T, Vasconcelos A, Venketasubramanian N, Violante F, Vlassov V, Vollset S, Wagner G, Wallin M, Wang L, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Westerman R, Wijeratne T, Wilkinson J, Williams H, Wiysonge C, Woldeyohannes S, Wolfe C, Won S, Xu G, Yadav A, Yakob B, Yan L, Yano Y, Yaseri M, Ye P, Yip P, Yonemoto N, Yoon S, Younis M, Yu C, Zaidi Z, Zaki M, Zeeb H, Zodpey S, Zonies D, Zuhlke L, Vos T, Lopez A, Murray C. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet 2016, 388: 1603-1658. PMID: 27733283, PMCID: PMC5388857, DOI: 10.1016/s0140-6736(16)31460-x.Peer-Reviewed Original ResearchConceptsAge-standardised DALY ratesNon-communicable diseasesSocio-demographic IndexHealthy life expectancyDALY ratesDisease burdenYears of lifeGlobal burdenStudy 2015Risk Factors Study 2015Non-fatal disease burdenHealth lossDisease Study 2015Age 65 yearsLife expectancyCause-specific mortalityHealth system performanceAge-specific death ratesCause mortalityGlobal DALYsTotal DALYsProportion of lifeTotal disabilityEpidemiological patternsEpidemiological transition
2012
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, AlMazroa M, Amann M, Anderson H, Andrews K, Aryee M, Atkinson C, Bacchus L, Bahalim A, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell M, Blore J, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce N, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett R, Byers T, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen J, Cheng A, Child J, Cohen A, Colson K, Cowie B, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Jarlais D, Devries K, Dherani M, Ding E, Dorsey E, Driscoll T, Edmond K, Ali S, Engell R, Erwin P, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane M, Flaxman S, Fowkes F, Freedman G, Freeman M, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez H, Hall W, Hoek H, Hogan A, Hosgood H, Hoy D, Hu H, Hubbell B, Hutchings S, Ibeanusi S, Jacklyn G, Jasrasaria R, Jonas J, Kan H, Kanis J, Kassebaum N, Kawakami N, Khang Y, Khatibzadeh S, Khoo J, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher J, Leigh J, Li Y, Lin J, Lipshultz S, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Memish Z, Mensah G, Merriman T, Micha R, Michaud C, Mishra V, Hanafiah K, Mokdad A, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson P, Nolla J, Norman R, Olives C, Omer S, Orchard J, Osborne R, Ostro B, Page A, Pandey K, Parry C, Passmore E, Patra J, Pearce N, Pelizzari P, Petzold M, Phillips M, Pope D, Pope C, Powles J, Rao M, Razavi H, Rehfuess E, Rehm J, Ritz B, Rivara F, Roberts T, Robinson C, Rodriguez-Portales J, Romieu I, Room R, Rosenfeld L, Roy A, Rushton L, Salomon J, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh G, Sleet D, Smith E, Smith K, Stapelberg N, Steenland K, Stöckl H, Stovner L, Straif K, Straney L, Thurston G, Tran J, Van Dingenen R, van Donkelaar A, Veerman J, Vijayakumar L, Weintraub R, Weissman M, White R, Whiteford H, Wiersma S, Wilkinson J, Williams H, Williams W, Wilson N, Woolf A, Yip P, Zielinski J, Lopez A, Murray C, Ezzati M. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 2012, 380: 2224-2260. PMID: 23245609, PMCID: PMC4156511, DOI: 10.1016/s0140-6736(12)61766-8.Peer-Reviewed Original ResearchConceptsSecond-hand smokeDisease Study 2010High blood pressureRisk factorsDisease burdenGlobal disease burdenTobacco smokingRisk factor exposureBlood pressureGlobal DALYsChildhood underweightRelative riskGlobal burdenStudy 2010Unimproved waterCommunicable diseasesHigher body mass indexHigh-income North AmericaAlcohol useChildhood communicable diseasesDisability-adjusted life yearsRisk factor clustersDietary risk factorsCause-specific deathBody mass indexDisability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, AlMazroa M, Alvarado M, Anderson H, Anderson L, Andrews K, Atkinson C, Baddour L, Bahalim A, Barker-Collo S, Barrero L, Bartels D, Basáñez M, Baxter A, Bell M, Benjamin E, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black J, Blencowe H, Blore J, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha T, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke C, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter C, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng A, Chou D, Chugh S, Coffeng L, Colan S, Colquhoun S, Colson K, Condon J, Connor M, Cooper L, Corriere M, Cortinovis M, de Vaccaro K, Couser W, Cowie B, Criqui M, Cross M, Dabhadkar K, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Jarlais D, Dharmaratne S, Dherani M, Diaz-Torne C, Dolk H, Dorsey E, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali S, Erskine H, Erwin P, Espindola P, Ewoigbokhan S, Farzadfar F, Feigin V, Felson D, Ferrari A, Ferri C, Fèvre E, Finucane M, Flaxman S, Flood L, Foreman K, Forouzanfar M, Fowkes F, Fransen M, Freeman M, Gabbe B, Gabriel S, Gakidou E, Ganatra H, Garcia B, Gaspari F, Gillum R, Gmel G, Gonzalez-Medina D, Gosselin R, Grainger R, Grant B, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa Y, Hall W, Haring D, Haro J, Harrison J, Havmoeller R, Hay R, Higashi H, Hill C, Hoen B, Hoffman H, Hotez P, Hoy D, Huang J, Ibeanusi S, Jacobsen K, James S, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas J, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo J, King C, Knowlton L, Kobusingye O, Koranteng A, Krishnamurthi R, Laden F, Lalloo R, Laslett L, Lathlean T, Leasher J, Lee Y, Leigh J, Levinson D, Lim S, Limb E, Lin J, Lipnick M, Lipshultz S, Liu W, Loane M, Ohno S, Lyons R, Mabweijano J, MacIntyre M, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis D, Marks G, Marks R, Matsumori A, Matzopoulos R, Mayosi B, McAnulty J, McDermott M, McGill N, McGrath J, Medina-Mora M, Meltzer M, Memish Z, Mensah G, Merriman T, Meyer A, Miglioli V, Miller M, Miller T, Mitchell P, Mock C, Mocumbi A, Moffitt T, Mokdad A, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch M, Mwaniki M, Naidoo K, Nair M, Naldi L, Narayan K, Nelson P, Nelson R, Nevitt M, Newton C, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer S, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian J, Rivero A, Patten S, Pearce N, Padilla R, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips M, Pierce K, Pion S, Polanczyk G, Polinder S, Pope C, Popova S, Porrini E, Pourmalek F, Prince M, Pullan R, Ramaiah K, Ranganathan D, Razavi H, Regan M, Rehm J, Rein D, Remuzzi G, Richardson K, Rivara F, Roberts T, Robinson C, De Leòn F, Ronfani L, Room R, Rosenfeld L, Rushton L, Sacco R, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel D, Scott J, Segui-Gomez M, Shahraz S, Shepard D, Shin H, Shivakoti R, Silberberg D, Singh D, Singh G, Singh J, Singleton J, Sleet D, Sliwa K, Smith E, Smith J, Stapelberg N, Steer A, Steiner T, Stolk W, Stovner L, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor H, Taylor J, Taylor W, Thomas B, Thomson W, Thurston G, Tleyjeh I, Tonelli M, Towbin J, Truelsen T, Tsilimbaris M, Ubeda C, Undurraga E, van der Werf M, van Os J, Vavilala M, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall D, Weinstock M, Weintraub R, Weisskopf M, Weissman M, White R, Whiteford H, Wiebe N, Wiersma S, Wilkinson J, Williams H, Williams S, Witt E, Wolfe F, Woolf A, Wulf S, Yeh P, Zaidi A, Zheng Z, Zonies D, Lopez A. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 2012, 380: 2197-2223. PMID: 23245608, DOI: 10.1016/s0140-6736(12)61689-4.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsGlobal disability-adjusted life yearsDisease burdenNon-communicable diseasesGlobal burdenDisability weightsCrude disability-adjusted life yearLife yearsCauses of DALYsNew disability weightsLower respiratory infectionsDisease Study 2010Ischemic heart diseaseSum of yearsNutritional disordersCause-specific mortalityMajor depressive disorderGlobal disease burdenHIV/AIDSContribution of deathsCause mortalityRespiratory infectionsSaharan AfricaInjury burdenHeart disease