2025
Spatial transcriptomics in inflammatory skin diseases using GeoMx digital spatial profiling: a practical guide for applications in dermatology
Cho C, Haddadi N, Kidacki M, Woodard G, Shakiba S, Yıldız-Altay Ü, Richmond J, Vesely M. Spatial transcriptomics in inflammatory skin diseases using GeoMx digital spatial profiling: a practical guide for applications in dermatology. JID Innovations 2025, 5: 100317. DOI: 10.1016/j.xjidi.2024.100317.Peer-Reviewed Original ResearchDigital spatial profilingInflammatory skin diseaseGeoMx Digital Spatial ProfilerSkin diseasesDiscoid lupus erythematosusNanoString GeoMx Digital Spatial ProfilingImmune milieuImmune microenvironmentLichen planusLupus erythematosusSingle cell RNA sequencingAberrant inflammationCell RNA sequencingSkin disease pathogenesisDisease pathogenesisManufacturer's guidelinesIndicators of diseaseDiseaseSpatial transcriptomics platformSkinTissue processing
2019
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis.
Albano-Aluquin S, Malysz J, Kidacki M, Ratnam M, Olsen NJ. An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis. Journal Of Visualized Experiments 2019 PMID: 30799840, DOI: 10.3791/58713.Peer-Reviewed Original ResearchConceptsGiant cell arteritisFolate receptor betaCell arteritisImmune microenvironmentChronic immune-mediated diseaseImmune-mediated diseasesTemporal artery biopsyT helper lymphocytesLarge-sized arteriesPro-inflammatory responseMyeloid leukemia cellsOcclusive symptomsTotal CD68Disease activityInflammatory disease researchArtery biopsyLymphohistiocytic inflammationSynovial macrophagesSized arteriesCD3 expressionTherapeutic responseVision lossImmunohistopathologic studyPathognomonic featuresIntimal hyperplasiaAn Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Albano-Aluquin S, Malysz J, Kidacki M, Ratnam M, Olsen N. An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis. Journal Of Visualized Experiments 2019 DOI: 10.3791/58713-v.Peer-Reviewed Case Reports and Technical NotesGiant cell arteritisCell arteritisImmune microenvironmentImmunohistopathologic studyArteritisMacrophages