2012
Neural Mechanisms of Decision Making in Hoarding Disorder
Tolin DF, Stevens MC, Villavicencio AL, Norberg MM, Calhoun VD, Frost RO, Steketee G, Rauch SL, Pearlson GD. Neural Mechanisms of Decision Making in Hoarding Disorder. JAMA Psychiatry 2012, 69: 832-841. PMID: 22868937, PMCID: PMC3506167, DOI: 10.1001/archgenpsychiatry.2011.1980.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingCerebral CortexDecision MakingDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsExpressed EmotionFemaleGyrus CinguliHoarding DisorderHospitals, VoluntaryHumansMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysObsessive BehaviorSickness Impact ProfileConceptsHealthy control subjectsObsessive-compulsive disorderAnterior cingulate cortexNeural mechanismsCingulate cortexBrain regionsNeural activityAppropriate emotional responsesFrontal brain regionsFunctional magnetic resonance imaging (fMRI) signalsPrevious neuroimaging studiesUnique diagnostic entityFunctional magnetic resonanceMagnetic resonance imaging signalsControl subjectsImpaired decisionInsula functionEmotional significanceAffective statesDepressive symptomsHoarding DisorderEmotional responsesNeuroimaging studiesPatientsPoor insight
2007
An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder
Stevens MC, Pearlson GD, Kiehl KA. An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2007, 164: 1737-1749. PMID: 17974940, DOI: 10.1176/appi.ajp.2007.06050876.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdolescent BehaviorAttentionAttention Deficit Disorder with HyperactivityAuditory PerceptionBrainBrain MappingCerebral CortexChildCognition DisordersDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsHemodynamicsHumansMagnetic Resonance ImagingMaleMemory DisordersOrientationOxygenPsychiatric Status Rating ScalesPsychomotor PerformanceConceptsAttention deficit hyperactivity disorderEvent-related potentialsFunctional magnetic resonance imagingDeficit hyperactivity disorderBrain regionsHyperactivity disorderHemodynamic activityThree-stimulus auditory oddball taskP3 event-related potentialEvent-related fMRI dataProcessing of targetsAbnormal hemodynamic activityWorking Memory DeficitsSlower task performanceAuditory oddball taskNovel environmental stimuliCortical brain regionsAttentional orientingOrient attentionADHD participantsCognitive processesCognitive representationsOddball studiesNeurobiological theoriesOddball stimuli
2006
Hippocampus Function Predicts Severity of Post-Traumatic Stress Disorder
Astur RS, St. Germain SA, Tolin D, Ford J, Russell D, Stevens M. Hippocampus Function Predicts Severity of Post-Traumatic Stress Disorder. Cyberpsychology Behavior And Social Networking 2006, 9: 234-240. PMID: 16640486, DOI: 10.1089/cpb.2006.9.234.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderVirtual Morris water taskFunctional magnetic resonance imagingMorris water taskPTSD severityStress disorderHippocampal activityWater taskSevere PTSD symptomsHippocampal-dependent tasksPTSD symptomsTask performanceMemory problemsHippocampal functionBrain structuresTaskAbnormal brain structureHippocampus functionAge-matched controlsMagnetic resonance imagingIQDisordersHippocampusTraumaResonance imaging
2005
fMRI in an oddball task: Effects of target‐to‐target interval
Stevens MC, Calhoun VD, Kiehl KA. fMRI in an oddball task: Effects of target‐to‐target interval. Psychophysiology 2005, 42: 636-642. PMID: 16364059, DOI: 10.1111/j.1469-8986.2005.00368.x.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEvent-related potentialsTarget stimuliOddball taskTarget intervalTask-relevant target stimuliP3 event-related potentialBilateral lateral prefrontal cortexTask-relevant stimuliTemporal-parietal junctionLateral prefrontal cortexAuditory oddball taskMemory templateNovel stimuliPrefrontal cortexHemodynamic activityAnterior cingulateNeural systemsStimuliPositive relationshipLarge sampleHealthy adultsNeuronal modulationEffect of targetMagnetic resonance imagingHemispheric differences in hemodynamics elicited by auditory oddball stimuli
Stevens MC, Calhoun VD, Kiehl KA. Hemispheric differences in hemodynamics elicited by auditory oddball stimuli. NeuroImage 2005, 26: 782-792. PMID: 15955488, PMCID: PMC2759643, DOI: 10.1016/j.neuroimage.2005.02.044.Peer-Reviewed Original ResearchConceptsNovel stimuliInfrequent targetsRight hemisphereHemispheric differencesGreater right hemisphere activationTask-relevant target stimuliAuditory oddball stimuliEvent-related fMRIParietal lobe activityRight hemisphere activationFrequent standard stimuliTask-irrelevant novel stimuliPrevious neuroimaging studiesHealthy adult participantsAttentional processesNovelty processingSalient stimuliTarget stimuliOddball stimuliOddball taskNeuroimaging studiesStandard stimuliInfrequent novelLeft hemisphereHemodynamic activity