2015
Psychiatric Symptoms in Youth with a History of Autism and Optimal Outcome
Orinstein A, Tyson KE, Suh J, Troyb E, Helt M, Rosenthal M, Barton ML, Eigsti IM, Kelley E, Naigles L, Schultz RT, Stevens MC, Fein DA. Psychiatric Symptoms in Youth with a History of Autism and Optimal Outcome. Journal Of Autism And Developmental Disorders 2015, 45: 3703-3714. PMID: 26155764, PMCID: PMC4609588, DOI: 10.1007/s10803-015-2520-8.Peer-Reviewed Original ResearchConceptsHigh-functioning autismAutism spectrum disorderHFA groupPsychiatric disordersHistory of autismSocial phobiaSpectrum disorderSpecific phobiaParent interviewsGeneralized anxietyElevated depressionAge 8AutismDSM-IV psychiatric disordersSubthreshold symptomsOO groupPsychiatric symptomsPhobiaCurrent ADHDYouthDisordersOptimal outcomesADHDPsychopathologyAnxiety
2012
A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort
Meda SA, Narayanan B, Liu J, Perrone-Bizzozero NI, Stevens MC, Calhoun VD, Glahn DC, Shen L, Risacher SL, Saykin AJ, Pearlson GD. A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort. NeuroImage 2012, 60: 1608-1621. PMID: 22245343, PMCID: PMC3312985, DOI: 10.1016/j.neuroimage.2011.12.076.Peer-Reviewed Original ResearchMeSH KeywordsAgedAlzheimer DiseaseBrainCanadaCohort StudiesData Interpretation, StatisticalFemaleGenetic Predisposition to DiseaseHumansMagnetic Resonance ImagingMaleMultivariate AnalysisPolymorphism, Single NucleotidePrevalencePrincipal Component AnalysisReproducibility of ResultsSensitivity and SpecificityUnited StatesConceptsLate-onset Alzheimer's diseaseMagnetic resonance imagingAlzheimer's diseaseOnset Alzheimer's diseaseAlzheimer's Disease Neuroimaging Initiative (ADNI) cohortElderly healthy controlsAmnestic mild cognitive impairmentDifferent brain regionsMild cognitive impairmentStructural MRI scansHealthy controlsCardiovascular diseaseInitiative cohortMRI scansPathologic processesCognitive impairmentResonance imagingBrain regionsSingle nucleotide polymorphism (SNP) variantsCaucasian adultsSubject cohortDiseasePhysiologic pathwaysCohortPolymorphism variants