White matter abnormalities in adolescents with major depressive disorder
Bessette KL, Nave AM, Caprihan A, Stevens MC. White matter abnormalities in adolescents with major depressive disorder. Brain Imaging And Behavior 2013, 8: 531-541. PMID: 24242685, DOI: 10.1007/s11682-013-9274-8.Peer-Reviewed Original ResearchConceptsMajor depressive disorderWhite matter abnormalitiesDiffusion tensor imagingDepressive disorderFrontal lobeWhole brainRegional white matter abnormalitiesRight thalamic radiationOlder depressed patientsTract-based spatial statisticsCorpus callosum genuFrontal lobe tractsFractional anisotropy valuesLower FAAbnormal white matter microstructureInferior longitudinal fasciculusWhite matter connectionsWhite matter microstructureInternal capsuleExternal capsuleFA abnormalitiesDepressed patientsHealthy controlsAdolescents ages 13Posterior limb