2013
DTI-measured white matter abnormalities in adolescents with Conduct Disorder
Haney-Caron E, Caprihan A, Stevens MC. DTI-measured white matter abnormalities in adolescents with Conduct Disorder. Journal Of Psychiatric Research 2013, 48: 111-120. PMID: 24139595, PMCID: PMC3863548, DOI: 10.1016/j.jpsychires.2013.09.015.Peer-Reviewed Original ResearchConceptsFractional anisotropyAxial diffusivityWhite matter microstructureMicrostructural abnormalitiesLong-range white matter connectionsWhite matter microstructural abnormalitiesWhite matter abnormalitiesDiffusion tensor imaging (DTI) findingsAnatomical connectivity abnormalitiesLower fractional anisotropySuperior corona radiataAbnormal white matter microstructureBrain white matter microstructureDifferent brain regionsWhite matter connectionsTemporal lobe regionsFronto-occipital fasciculusTwo-sample t-testFunctional neuroimaging studiesCD ageCD adolescentsMajor white matterImaging findingsRadial diffusivity measurementsStudy group
2012
A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort
Meda SA, Narayanan B, Liu J, Perrone-Bizzozero NI, Stevens MC, Calhoun VD, Glahn DC, Shen L, Risacher SL, Saykin AJ, Pearlson GD. A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort. NeuroImage 2012, 60: 1608-1621. PMID: 22245343, PMCID: PMC3312985, DOI: 10.1016/j.neuroimage.2011.12.076.Peer-Reviewed Original ResearchMeSH KeywordsAgedAlzheimer DiseaseBrainCanadaCohort StudiesData Interpretation, StatisticalFemaleGenetic Predisposition to DiseaseHumansMagnetic Resonance ImagingMaleMultivariate AnalysisPolymorphism, Single NucleotidePrevalencePrincipal Component AnalysisReproducibility of ResultsSensitivity and SpecificityUnited StatesConceptsLate-onset Alzheimer's diseaseMagnetic resonance imagingAlzheimer's diseaseOnset Alzheimer's diseaseAlzheimer's Disease Neuroimaging Initiative (ADNI) cohortElderly healthy controlsAmnestic mild cognitive impairmentDifferent brain regionsMild cognitive impairmentStructural MRI scansHealthy controlsCardiovascular diseaseInitiative cohortMRI scansPathologic processesCognitive impairmentResonance imagingBrain regionsSingle nucleotide polymorphism (SNP) variantsCaucasian adultsSubject cohortDiseasePhysiologic pathwaysCohortPolymorphism variants
2011
Cortical Thickness and Folding Deficits in Conduct-Disordered Adolescents
Hyatt CJ, Haney-Caron E, Stevens MC. Cortical Thickness and Folding Deficits in Conduct-Disordered Adolescents. Biological Psychiatry 2011, 72: 207-214. PMID: 22209639, PMCID: PMC3367056, DOI: 10.1016/j.biopsych.2011.11.017.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAttention Deficit Disorder with HyperactivityCerebral CortexChildConduct DisorderFemaleFunctional LateralityHumansImage Processing, Computer-AssistedLinear ModelsMagnetic Resonance ImagingMaleNeuropsychological TestsPrefrontal CortexPsychiatric Status Rating ScalesPsychomotor PerformanceSoftwareConceptsCortical thicknessParietal lobeBrain regionsControl subjectsParacentral lobuleConduct disorderThinner cortexCD participantsTemporal lobe structural abnormalitiesPure conduct disorderLocal gyrification indexBrain structure imagesAnterior brain regionsDifferent brain regionsSurface-based morphometryPosterior brain regionsTemporoparietal junctionBrain abnormalitiesGyrification indexTemporal lobeAnterior cingulateFrontal lobeDorsomedial prefrontalStructural abnormalitiesOrbitofrontal cortex