2024
A randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD
Sullivan A, Anderson J, Beatty M, Choi J, Jaccard J, Hawkins K, Pearlson G, Stevens M. A randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD. Behaviour Research And Therapy 2024, 181: 104615. PMID: 39173523, PMCID: PMC11465636, DOI: 10.1016/j.brat.2024.104615.Peer-Reviewed Original ResearchExecutive working memoryAttention-deficit/hyperactivity disorderWorking memory trainingMemory trainingExecutive working memory taskIncreased working memory capacityMedium effect size improvementsEffect size improvementsSelf-rated motivationIntervention participantsTarget engagementTrial retentionWorking memoryAttention-deficit/hyperactivityDifficulty manipulationPlacebo-controlled studyMemory capacityTask accuracySize improvementsMemory contentIntervention tolerabilityTraining targetBehavioral changesPrimary outcome measureCoaching sessions
2015
A preliminary study of the effects of working memory training on brain function
Stevens MC, Gaynor A, Bessette KL, Pearlson GD. A preliminary study of the effects of working memory training on brain function. Brain Imaging And Behavior 2015, 10: 387-407. PMID: 26138580, PMCID: PMC4698365, DOI: 10.1007/s11682-015-9416-2.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderWM trainingMemory trainingBrain regionsDifferent neural correlatesBrain functionADHD symptom severityTraining-related changesTemporal lobe regionsDifferent symptom typesWM abilityExecutive processingWM performanceFMRI taskFrontoparietal circuitsNeural correlatesBrain activationHyperactivity disorderNeuropsychological testsNeural changesBrain activityTask phasesLobe regionsActivation gainControl participants
2014
Brain activity in predominantly-inattentive subtype attention-deficit/hyperactivity disorder during an auditory oddball attention task
Orinstein AJ, Stevens MC. Brain activity in predominantly-inattentive subtype attention-deficit/hyperactivity disorder during an auditory oddball attention task. Psychiatry Research 2014, 223: 121-128. PMID: 24953999, PMCID: PMC4120259, DOI: 10.1016/j.pscychresns.2014.05.012.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderAttention taskADHD subtypesHyperactivity disorderNovel stimuliBrain activityMemory-related cognitive processesPrevious functional neuroimaging studiesBilateral superior temporal gyrusRight posterior parietal cortexNumerous cognitive tasksFunctional neuroimaging studiesInfrequent target stimuliAge-matched control participantsSuperior temporal gyrusPosterior parietal cortexTemporal lobe structuresGreater hemodynamic activityAttentional orientingCognitive processesCognitive tasksTarget stimuliInattentive subtypeLateral temporal lobe structuresAttention deficits
2011
The Effects of Stimulant Medication on Working Memory Functional Connectivity in Attention-Deficit/Hyperactivity Disorder
Wong CG, Stevens MC. The Effects of Stimulant Medication on Working Memory Functional Connectivity in Attention-Deficit/Hyperactivity Disorder. Biological Psychiatry 2011, 71: 458-466. PMID: 22209640, PMCID: PMC4120250, DOI: 10.1016/j.biopsych.2011.11.011.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderFunctional magnetic resonance imagingFunctional connectivityFMRI taskHyperactivity disorderStimulant medicationNetwork engagementMemory fMRI taskFrontoparietal brain networksBrain regionsFrontoparietal brain regionsConnectivity changesMemory reaction timeVentrolateral prefrontal cortexAdditional brain regionsGroup independent component analysisMedication-related changesFunctional connectivity analysisRegional functional connectivityFunctional connectivity changesMemory performanceRepeated-measures t-testBrain activationIndependent component analysisRetrieval phase
2002
A Review of Adult ADHD: A Neuropsychological and Neuroimaging Perspective
Kaplan R, Stevens M. A Review of Adult ADHD: A Neuropsychological and Neuroimaging Perspective. CNS Spectrums 2002, 7: 355-362. PMID: 15122107, DOI: 10.1017/s1092852900017818.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderAdult attention-deficit/hyperactivity disorderPathophysiology of ADHDFunctional magnetic resonance imagingFrontal lobe functionNeuropsychological test performanceCore ADHD symptomsPsychiatric disordersSimilar psychiatric disordersNeuroimaging PerspectiveADHD symptomsLobe functionHyperactivity disorderNeuropsychological testsTest performanceNeuroimaging technologiesDevelopmental disordersMost theoriesUnitary disorderStatistical ManualMental disordersFourth EditionDisordersDopaminergic transmissionCurrent thinking