2004
Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortex
Schwartz ML, Vaccarino F, Chacon M, Yan WL, Ment LR, Stewart WB. Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortex. Seminars In Perinatology 2004, 28: 379-388. PMID: 15693394, DOI: 10.1053/j.semperi.2004.10.009.Peer-Reviewed Original ResearchConceptsDays of hypoxiaPreterm birth resultsNeuronal sizeBirth resultsHypoxic exposureCell numberChronic neonatal hypoxiaChronic sublethal hypoxiaNeonatal rodent modelPerinatal period altersRat cerebral cortexNeuronal cell numberBcl-2Glial cell numbersNormoxic environmentPostnatal day 3Cortical cell numberSignificant neurodevelopmental disabilitiesWestern blot analysisPreterm birthNeonatal hypoxiaNormoxic exposureCerebral cortexChronic hypoxiaControl pups
1997
Chronic postnatal hypoxia increases the numbers of cortical neurons
Stewart W, Ment L, Schwartz M. Chronic postnatal hypoxia increases the numbers of cortical neurons. Brain Research 1997, 760: 17-21. PMID: 9237513, DOI: 10.1016/s0006-8993(97)00271-0.Peer-Reviewed Original ResearchConceptsCortical neuronsHypoxic ratsSublethal hypoxiaChronic postnatal hypoxiaChronic sublethal hypoxiaDays of hypoxiaCell deathPostnatal hypoxiaPremature infantsNeuronal densityBrain weightChronic hypoxiaCortical volumeClinical problemAnimal modelsCortical cell deathRatsThird dayHypoxiaLower bodyNeurodevelopmental disordersNeuronsConsiderable evidenceProlonged periodDeath