Opioid use disorder risk alleles in self-reported assigned African American/Afro-Caribbean and European biogeographical genetic ancestry groups and in males and females
Sprague J, Freiermuth C, Lambert J, Braun R, Frey J, Bachmann D, Bischof J, Beaumont L, Lyons M, Pantalon M, Punches B, Ancona R, Kisor D. Opioid use disorder risk alleles in self-reported assigned African American/Afro-Caribbean and European biogeographical genetic ancestry groups and in males and females. The Pharmacogenomics Journal 2024, 24: 23. PMID: 39090078, PMCID: PMC11294185, DOI: 10.1038/s41397-024-00337-y.Peer-Reviewed Original ResearchConceptsOpioid use disorderAncestry groupsVariant carriersSelf-reportGenetic ancestry groupsVariant carrier statusMultiple logistic regression analysisAssociated with opioid use disorderLogistic regression analysisRisk allelesEmergency departmentCarrier statusAdult patientsMedical CenterOpioidVariantsRegression analysisSexSample sizePredicted probabilityAllelesRs2740574