c-Met Must Translocate to the Nucleus to Initiate Calcium Signals* ♦
Gomes DA, Rodrigues MA, Leite MF, Gomez MV, Varnai P, Balla T, Bennett AM, Nathanson MH. c-Met Must Translocate to the Nucleus to Initiate Calcium Signals* ♦. Journal Of Biological Chemistry 2007, 283: 4344-4351. PMID: 18073207, PMCID: PMC2825875, DOI: 10.1074/jbc.m706550200.Peer-Reviewed Original ResearchConceptsHepatocyte growth factorC-MetAdaptor protein Gab1Protein Gab1C-Met signalingImportin beta1Plasma membraneReceptor c-MetBisphosphate hydrolysisCell proliferationCalcium signalsPathwayTrisphosphate formationGrowth factorCytoplasmTranslocationNucleusGab1PhosphatidylinositolSignalingInositolDifferentiationProliferationMembraneBeta1