2022
Lipid‐lowering treatment among older patients with atherosclerotic cardiovascular disease
Nanna M, Nelson A, Haynes K, Shambhu S, Eapen Z, Cziraky M, Calvert S, Pagidipati N, Granger C. Lipid‐lowering treatment among older patients with atherosclerotic cardiovascular disease. Journal Of The American Geriatrics Society 2022, 71: 1243-1249. PMID: 36538393, PMCID: PMC10089944, DOI: 10.1111/jgs.18172.Peer-Reviewed Original ResearchConceptsHigh-intensity statinsLipid-lowering therapyModerate-intensity statinsU.S. older adultsOlder adultsPCSK9 inhibitorsNon-statin lipid-lowering therapyMulticenter retrospective cohort studyRetrospective cohort studyMinority of patientsAtherosclerotic cardiovascular diseaseCoronary artery diseaseEligible older adultsCohort studyOlder patientsOverall cohortArtery diseaseIntensive treatmentCardiovascular diseaseASCVDSecondary measuresStatinsUntreated individualsPatientsTherapy
2019
The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts
Nanna MG, Navar AM, Wojdyla D, Peterson ED. The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts. Journal Of The American Geriatrics Society 2019, 67: 2560-2567. PMID: 31411740, PMCID: PMC6898756, DOI: 10.1111/jgs.16123.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseLow-density lipoprotein cholesterolIncident atherosclerotic cardiovascular diseaseRisk factorsEvent ratesLipoprotein cholesterolPooled cohortCardiovascular diseaseMultivariable-adjusted Cox proportional hazards modelsElevated low-density lipoprotein cholesterolIndividual level cohort dataCox proportional hazards modelOlder adultsASCVD event ratesCVD risk factorsCVD event ratesProspective cohort studyPresence of hyperlipidemiaProportional hazards modelNational InstituteCohort studyCVD riskMedian ageMedian LDLUnadjusted analysesPractice-level variation in statin use and low-density lipoprotein cholesterol control in the United States: Results from the Patient and Provider Assessment of Lipid Management (PALM) registry
Nanna MG, Navar AM, Wang TY, Li S, Virani SS, Li Z, Robinson JG, Roger VL, Wilson PWF, Goldberg AC, Koren A, Louie MJ, Peterson ED. Practice-level variation in statin use and low-density lipoprotein cholesterol control in the United States: Results from the Patient and Provider Assessment of Lipid Management (PALM) registry. American Heart Journal 2019, 214: 113-124. PMID: 31202098, PMCID: PMC6639125, DOI: 10.1016/j.ahj.2019.05.009.Peer-Reviewed Original ResearchConceptsLow-density lipoprotein cholesterol controlMedian odds ratioAtherosclerotic cardiovascular diseaseStatin useStatin intensityStatin therapyCholesterol controlProvider assessmentGuideline-recommended statin intensityGuideline-recommended intensityLipid Management (PALM) registrySecondary prevention patientsLDL-C levelsPractice-level variationEligible patientsStatin recommendationsStatin treatmentManagement RegistryGuideline recommendationsPatient's likelihoodUS patientsSimilar patientsTreatment indicationsUS clinicsOdds ratio
2018
Association of Patient Perceptions of Cardiovascular Risk and Beliefs on Statin Drugs With Racial Differences in Statin Use: Insights From the Patient and Provider Assessment of Lipid Management Registry
Nanna MG, Navar AM, Zakroysky P, Xiang Q, Goldberg AC, Robinson J, Roger VL, Virani SS, Wilson PWF, Elassal J, Lee LV, Wang TY, Peterson ED. Association of Patient Perceptions of Cardiovascular Risk and Beliefs on Statin Drugs With Racial Differences in Statin Use: Insights From the Patient and Provider Assessment of Lipid Management Registry. JAMA Cardiology 2018, 3: 739-748. PMID: 29898219, PMCID: PMC6656582, DOI: 10.1001/jamacardio.2018.1511.Peer-Reviewed Original ResearchMeSH KeywordsAgedAtherosclerosisAttitude to HealthBlack or African AmericanCholesterol, LDLFemaleGuideline AdherenceHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasMaleMiddle AgedPerceptionPrimary PreventionRegistriesRiskSecondary PreventionSocial ClassUnited StatesWhite PeopleConceptsAfrican American patientsAfrican American individualsStatin therapyStatin useWhite individualsAmerican patientsPatients' beliefsProvider assessmentCardiology/American Heart Association guidelinesMedian low-density lipoprotein (LDL) cholesterol levelLow-density lipoprotein cholesterol levelsGuideline-recommended statin therapyAtherosclerotic cardiovascular disease riskAmerican Heart Association guidelinesGuideline-recommended intensityLipid Management (PALM) registryHeart Association guidelinesLipoprotein cholesterol levelsCardiovascular disease riskAmerican individualsCommunity health care practicesClinician differencesHealth care practicesPALM registryCardiovascular risk