2022
High-Intensity Statin Use Among Patients With Atherosclerosis in the U.S.
Nelson AJ, Haynes K, Shambhu S, Eapen Z, Cziraky MJ, Nanna MG, Calvert SB, Gallagher K, Pagidipati NJ, Granger CB. High-Intensity Statin Use Among Patients With Atherosclerosis in the U.S. Journal Of The American College Of Cardiology 2022, 79: 1802-1813. PMID: 35512860, PMCID: PMC9344279, DOI: 10.1016/j.jacc.2022.02.048.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseHigh-intensity statinsStatin useYounger patientsFemale patientsHigh-intensity statin useHigher Charlson comorbidity scoreAppropriate statin useNew guideline recommendationsCharlson comorbidity scoreRetrospective cohort studyPeripheral artery diseaseModerate-intensity statinsMultivariable logistic regressionCommercial health plansMedical claims dataComorbidity scoreIndex dateCohort studyOlder patientsPreventive therapyStatin usersArtery diseaseContemporary cohortGuideline recommendations
2019
Sex Differences in the Use of Statins in Community Practice
Nanna MG, Wang TY, Xiang Q, Goldberg AC, Robinson JG, Roger VL, Virani SS, Wilson PWF, Louie MJ, Koren A, Li Z, Peterson ED, Navar AM. Sex Differences in the Use of Statins in Community Practice. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005562. PMID: 31416347, PMCID: PMC6903404, DOI: 10.1161/circoutcomes.118.005562.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCommunity Health ServicesDyslipidemiasFemaleGuideline AdherenceHealth Knowledge, Attitudes, PracticeHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMedication AdherenceMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Primary PreventionRegistriesRisk AssessmentRisk FactorsSecondary PreventionSex FactorsTime FactorsTreatment OutcomeTreatment RefusalUnited StatesConceptsStatin therapyStatin treatmentStatin useCardiology/American Heart Association cholesterol guidelinesAmerican Heart Association cholesterol guidelinesGuideline-recommended statin intensityHeart Association cholesterol guidelinesSex differencesAggressive lipid managementGuideline-recommended intensityLipid Management (PALM) registrySecondary prevention indicationUse of statinsAtherosclerotic cardiovascular diseaseMultivariable logistic regressionCholesterol guidelinesStatin dosingStatin intensityLipid managementClinical characteristicsNationwide registryPrevention indicationMale patientsManagement RegistryFemale patients