Effects of Chloride Restriction and Depletion on Acid-Base Balance and Chloride Conservation in the Rat
Luke R, Warren Y, Kashgarian M, Levitin H. Effects of Chloride Restriction and Depletion on Acid-Base Balance and Chloride Conservation in the Rat. Clinical Science 1970, 38: 385-396. PMID: 5442558, DOI: 10.1042/cs0380385.Peer-Reviewed Original ResearchConceptsUrinary net acid excretionNet acid excretionAcid excretionPlasma bicarbonateProximal tubulesBicarbonate absorptionDietary chloride restrictionProximal tubular absorptionUrinary acid excretionEndogenous acid productionLow chloride dietDegree of elevationAcid-base balanceDietary sodiumPlasma chlorideSerum bicarbonateTubular absorptionPhosphate excretionRespiratory acidosisMicropuncture experimentsDepleted ratsHypochloraemiaRatsExcretionRates of sodiumMicropuncture Studies of Chloride and Bicarbonate Absorption in the Proximal Renal Tubule of the Rat in Respiratory Acidosis and in Chloride Depletion
Warren Y, Luke R, Kashgarian M, Levitin H. Micropuncture Studies of Chloride and Bicarbonate Absorption in the Proximal Renal Tubule of the Rat in Respiratory Acidosis and in Chloride Depletion. Clinical Science 1970, 38: 375-383. PMID: 5442557, DOI: 10.1042/cs0380375.Peer-Reviewed Original ResearchConceptsProximal tubulesBicarbonate absorptionRespiratory acidosisMicropuncture studiesPlasma bicarbonateProximal tubular absorptionUrinary acid excretionUrinary chloride excretionLow chloride dietSignificant increaseProximal renal tubulesSodium restrictionHr of exposureTubular absorptionChloride excretionAcid excretionRenal tubulesChloride absorptionHr exposureReciprocal patternDistal sitesTubulesAcidosisExcretionChloride depletion