2019
On‐label compared to off‐label four‐factor prothrombin complex concentrate use: a retrospective, observational study
Cho B, Jung Y, DeMario V, Lau E, Podlasek S, Grant M, Gehrie E, Frank S. On‐label compared to off‐label four‐factor prothrombin complex concentrate use: a retrospective, observational study. Transfusion 2019, 59: 2678-2684. PMID: 31121073, DOI: 10.1111/trf.15355.Peer-Reviewed Original ResearchConceptsUrgent reversalLabel useMortality rateFour-factor prothrombin complex concentrateAcute major bleedingVitamin K antagonistsProthrombin complex concentrate useProthrombin complex concentrateOff-label useCoagulation factor deficienciesHospital mortalityMajor bleedingK antagonistsPatient characteristicsClinical outcomesBlood utilizationExpensive treatment optionsLabel indicationsSingle institutionTreatment optionsComplex concentrateObservational studyFactor deficiencyInvasive proceduresOff label
2017
Epidemiology of septic meningitis associated with neuraxial anesthesia: a historical review and meta-analysis.
Zorrilla-Vaca A, Healy R, Rivera-Lara L, Grant M, Maragakis L, Escandón-Vargas K, Mirski M. Epidemiology of septic meningitis associated with neuraxial anesthesia: a historical review and meta-analysis. Minerva Anestesiologica 2017, 84: 363-377. PMID: 29108403, DOI: 10.23736/s0375-9393.17.11920-6.Peer-Reviewed Original ResearchConceptsSeptic meningitisNeuraxial anesthesiaEpidural anesthesiaOverall mortality rateCommon risk factorsCase report articlesSpinal anesthesiaSymptom onsetEpidural anestheticsTrue incidenceRisk factorsRegional anesthesiaObservational studyLocal anestheticsMeningitisEpidemiological studiesMortality rateAnesthesiaSystematic reviewSurgical masksCommon bacteriaFrequent formEpiduralStaphylococcus aureusAnesthetics