2022
Early Return to Intended Oncologic Therapy after implementation of an Enhanced Recovery After Surgery pathway for gastric cancer surgery
Garcia-Nebreda M, Zorrilla-Vaca A, Ripollés-Melchor J, Abad-Motos A, Alvaro Cifuentes E, Abad-Gurumeta A, Mena G, Grant M, Paseiro-Crespo G. Early Return to Intended Oncologic Therapy after implementation of an Enhanced Recovery After Surgery pathway for gastric cancer surgery. Langenbeck's Archives Of Surgery 2022, 407: 2293-2300. PMID: 35441358, DOI: 10.1007/s00423-022-02515-7.Peer-Reviewed Original ResearchConceptsGastric cancer surgeryCancer surgeryERAS pathwayAdjuvant therapySurgery pathwayOncologic therapyGastric adenocarcinomaEnhanced recoveryPostoperative oncologic outcomesPre-ERAS periodERAS groupHospital stayOncologic outcomesPrimary outcomeShorter LOSResultsSeventy patientsEarly returnSurgeryIntervention studiesTherapyPatientsMedian differenceAdenocarcinomaOutcomesPathway
2021
Institutional factors associated with adherence to enhanced recovery protocols for colorectal surgery: Secondary analysis of a multicenter study
Zorrilla-Vaca A, Stone A, Ripolles-Melchor J, Abad-Motos A, Ramirez-Rodriguez J, Galan-Menendez P, Mena G, Grant M, Group P, Garcia-Perez C, Higuera-Míguelez E, Marcos-Vidal J, Merino-García M, Rubio-López A, Pascual-Diez M, García-Miguel F, Cabezudo-Sanjose L, Martínez-Díaz R, Alegría-Rebollo S, González-Rodríguez J, Vega-Cruz M, Martínez-Ragüés G, Gómez-Ríos M, Mosquera-Rodríguez E, Del-Río-Regueira S, Bustos-García D, Sánchez-Conde M, Rodríguez-Calvo A, Hernández-Valero M, Angoso-Clavijo M, González-Fernández L, Bravo-Riaño M, Arnes-Muñoz M, Perez-Valdivieso J, Martin-Vizcaino M, Hernandez-Garcia S, Yoldi-Murillo F, Salvador-Bravo M, Rubial-Alvarez M, Oteiza-Martinez F, Balen-Rivera E, Garcia-Erce J, Zugasti-Murillo A, Petrina-Jáuregui M, Bustos-Molina F, Paz-Martín D, Vázquez-Vicente B, González-López L, Mínguez-Marín C, Diz-Jueguen S, Seoane-Antelo J, Ballinas-Miranda J, Carrera-Dacosta E, Barreiro-Domínguez E, Piñeiro-Teijeiro A, Sanchez-Santos R, Varela-Duran M, Diaz-Parada P, Calero-Lillo A, López-Lara M, Muñoz-Collado S, Valverde-Sintas J, Aznar-Puig S, Troyano-Escribano D, Marmaña-Mezquita S, Fernanz-Antón J, Catot-Alemany L, Balust J, Ubré M, Ferrando-Ortolá C, Martínez-Pallí G, Ibarzabal A, Lacy A, Sánchez-Martín R, Martins-Cruz K, Pérez-Jiménez P, Casans-Francés R, Longás J, Rodríguez J, Mugarra-Llopis A, Crisan C, Gracia-Ferrándiz E, Romero-Vargas E, Soro-Domingo M, Rodríguez-Jiménez R, Prada-Martin B, Muñoz-Hernández H, Herrera J, Cocho-Crespo S, Fernández-Caballero S, Flores-Crespo M, Vázquez-Fernández A, Brugiotti C, Ollé-Sese E, Houghton-Acuña C, López-Doucil M, Tarazona-López E, BEL-Marcobal I, González-Cogollor S, Llácer-Pérez M, Arias-Romano A, Arrabal-Taborda M, Caballero-Domínguez M, García-López R, Ontoria-Muriel J, Vivó-Blasco A, Blanco F, DEL-Cojo-Peces E, Tena-Guerrero J, Landaluce-Olavarria A, Badiola I, Calvo M, DE-Andres U, Portugal-Porras V, Ugarte-Sierra B, Pedregosa-Sanz A, Perelló-Cerdà L, Rodríguez-Téllez Y, Grössl-Meleán J, Viñas-Truñén X, Alday-Muñoz E, Bermejo-Marcos E, Alonso-Casado P, Gimeno-Calvo F, Rodriguez-Sánchez A, Montes-López C, Álvarez-Llano L, FAS-Vicent M, Ortega-Monzó J, Flores-Flores G, Tristancho J, Marmaña-Mezquita S, Bayo-Sans M, Deiros-Garcia M, Fernanz-Antón J, GIL-Gómez M, Parra L, Tejedor-DE-LA-Fuente V, Jericó-Alba C, Borrell-Brau N, Camacho-Martín D, Ortiz-DE-Zarate J, López-Ruiz D, Rodriguez-Bustamante V, Martinez-Vilalta M, Amoros-Ruiz D, Sadurni-Sarda M, Matas F, Giordano H, Peña J, Olmedilla-Arnal L, Benito-SAZ P, López-GIL E, Ruiz-Ortega A, Zapatero-García S, DEL-Valle-García E, Soria-Aledo V, Pérez-Guarinos C, Pellicer-Franco E, Valero-Navarro G, Mengual-Ballester M, García-Marín J, Romero-Simó M, Caravaca-García I, Blasco-Segura T, Campo-Betancourth C, Costa-Navarro R, Jordá-Sanz L, DE-Miguel-Cabrera M, España-Pamplona J, GIL-Trujillo S, Redondo-Calvo F, Baladrón-Gónzalez V, Moreno-Ballesteros R, Muñoz-Rodes J, Miranda E, Roselló-Chornet M, Alós-Zaragoza L, Catalá-Bauset J, Pallardo-López M, Almenara-Almenara N, Muñoz-Devesa L, Alcaide-Pardo B, Gimeno-Fernández P, Gómez-Agraz J, Iglesias-Morales C, Ordoñez-Enireb P, Ríos-Villalba A, Rodríguez-Pinto J, Sánchez-Cortés S, Montoya-Tabares M, Ruiz V, González-Sánchez F, Soriano-Giménez V, Muñoz-Camarena J, Benavides-Buleje J, Estupiñán-Jiménez J, Portero-Larragueta I, Alias D, Alberola-Estellés M, Díaz-Cambronero Ó, Matoses-Jaén M, Ruiz-Boluda M, Maristany-Bienert C, Pardo-López J, Ramiro-Ruiz Á, García P, Martínez-DE-Guereñu A, Montalbán B, Olea C, Benguría D, Silva J, Calderón A, Escoll-Rufino J, Cerdan-Santacruz C, Sierra-Grañón J, Rufas-Acín M, Mestres-Petit N, Penagos-Saavedra I, Moreno-Castilla C, Riera-RIU J, Cuellar-Martínez A, González-Álvarez R, Sánchez-Merchante M, García-DEL-Valle-Y-Manzano S, García-Zamorano S, Gijón-Herreros N, Robles-Ángel P, Logroño-Ejea M, Sanllorente-Sebastian R, Villalain-Perez M, Siclama-Stroe M, Benítez-Villar J, Sánchez-Campos A, Martínez-Ruiz A, Alonso-Carnicero P, DE-LA-Torre-González F, Naranjo-Checa C, Pereira-Pérez F, Ruiz-Ucar E, Rivera A, GIL-Lapetra C, Roca-Castillo E, Mariscal-Flores M, Morales-Cayuela M, Alonso-Ramos I, Jiménez-Carneros V, Casalduero-Garcia L, Jimenez-Miramón J, José L, Nogués-Ramia E, Sosa-Quesada Y, Gómez A, Martínez-Meco-Ortiz L, Cabellos-Olivares M, Rodríguez-Fraile J, Labalde-Martínez M, Ramos-Rodríguez, Nacarino-Alcorta B, Fernández-García R, DE-LA-Quintana-Gordon B, Drewniak J, Senra-L F, Galindo-Jara P, Gallardo-Herrera A, García-Llorente C, Colao-García L, Rellan-Álvarez L, Miro-Murillo M, Flores-Risco S, Serrat-Puyol J, Medina-Gallardo A, Mitsahid-Curbelo-Peña Y, Orenzana, Abad-Motos A, Abad-Gurumeta A, Aracil-Escoda N, Martínez-Hurtado E, Nozal-Mateo B, Sáez-Ruiz E, Salvachua-Fernández R, Ripollés-Melchor J, DE-Fuenmayor-Valera M, Sánchez E, Toribio B, Navarro-Sánchez A, López-Fernández J, Montesdeoca-Cabrera D, Alcalá-Serrano F, Sancho-DE-Avila A, Diaz-Carrasco S, Martín-Martín A, Suarez-DE-LA-Rica A, UÑA-Orejón R, Maseda E, Tejón-Pérez G, Alfaro-Martínez M, Alonso-Fernández M, Álvarez-Cebrián M, Álvarez-DEL-Vayo-Rodríguez M, Carrillo-Rivas M, Fernández-Rodríguez M, Trabanco-Morán S, Rábago-Morán J, Martínez-Ubieto J, Pascual-Bellosta A, Ortega-Lucea S, Santero-Ramirez M, Duque-Mallen M, Aragon-Benedi C, Vallejo-Tarrat A, Colillas-Calvet C, Laso M, Martinez-Cabañero J, Hernández-Salván J, Ledesma-Muñoz B, Ochoa-Osorio C, Sanz-García M, Herrero-Garrote B, Blázquez-Martin A, Díez-Alonso M, Hernández-Juara P, Muguerza-Huguet J, Barbero-Mielgo M, SAN-Antonio-SAN-Román B, Alonso-Aguilar L, Molnar V, Delgado-Naviero M, Meléndez-Leal E, Cavero-García V, Fernández-Sánchez Á, Cubek-Quevedo D, Munar R, Pradilla F, Serrano A, Balvís A, Berruezo A, Esparza E, HOZ I, Palavicini A, Pereira L, Vega X, Villahoz J, Villanueva G, Alonso-Fernández J, Aldecoa C, Bolaño-Pérez C, Villán-González T, Batalla A, Azparren G, Basttita M, Felipe M, Cueva L, Gine M, Gómez-Caro A, India I, Piñol S, Esteve-Pérez N, Mora-Fernández C, Ferrer-Robles A, Segura-Sampedro J, Alonso-Hernández N, Camps-Cervantes A, Chocrón-DA-Prat I, Coronado-Silva C, Duque-Santos H, Esclapez-Sempere E, Galan-Menéndez P, Matarín-Olmo S, Tormos-Pérez M, Villarino-Villa L, Bergés-Gutiérrez H, Aisa-Gasca M, Arbona-Camillero V, Bautista-González J, Carballido-Pascual F, Gutiérrez-Moreno M, Muñoz-Durán A, Cañete-Gómez J, Cáceres-Fabrega E, Lorente-Herce J, Mulet-Zayas O, Gómez-Pérez R, Monje-Salazar C, Lobato-Bancalero L, Torres-Moreno C, Sanchez-Cárdenas E, Daza-González J, Sanchez-Viguera T, DEL-Fresno-Asensio A, Bermudez-Román L, Jover-Pinillos J, Orts-Micó F, Cózar-Lozano C, Blasco-Delgado O, Nonnemacher-SAN-Julián A, Pérez J, Cruces L, Renedo-Corcóstegui P. Institutional factors associated with adherence to enhanced recovery protocols for colorectal surgery: Secondary analysis of a multicenter study. Journal Of Clinical Anesthesia 2021, 74: 110378. PMID: 34144497, DOI: 10.1016/j.jclinane.2021.110378.Peer-Reviewed Original ResearchConceptsEnhanced recovery protocolRegular multidisciplinary meetingsColorectal surgeryMultidisciplinary meetingCase volumeSecondary analysisFaster functional recoveryBetter patient satisfactionLow complication rateMultivariable linear regressionRecovery protocolHospital stayERAS implementationComplication rateFunctional recoveryMedian adherenceMulticenter studyPatient satisfactionMultivariable regressionNationwide studySurgery SocietyAnesthesia staffEnhanced recoveryMultidisciplinary teamSurgery
2020
Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study
Zorrilla-Vaca A, Mena G, Ripolles-Melchor J, Abad-Motos A, Aldecoa C, Lorente J, Ramirez-Rodriguez J, Grant M. Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study. The American Surgeon 2020, 87: 1189-1195. PMID: 33342254, DOI: 10.1177/0003134820973365.Peer-Reviewed Original ResearchConceptsGoal-directed fluid therapyEnhanced recovery programmeAcute kidney injurySurgical site infectionColorectal surgeryPostoperative outcomesFluid therapyPostoperative acute kidney injuryPropensity score-matched analysisComparable baseline demographicsMajor postoperative outcomesAdequate tissue perfusionRates of morbidityHospital stayKidney injuryBaseline demographicsCohort studyConventional careERAS programAnastomotic dehiscenceMajor surgerySite infectionPulmonary edemaMulticenter studyTherapy patients
2019
Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery
Grant M, Gibbons M, Ko C, Wick E, Cannesson M, Scott M, McEvoy M, King A, Wu C. Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 30113392, DOI: 10.1213/ane.0000000000003696.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesiaBariatric SurgeryEvidence-Based MedicineHealth Services ResearchHumansOutcome and Process Assessment, Health CarePatient SafetyPostoperative ComplicationsPractice Guidelines as TopicQuality ImprovementQuality Indicators, Health CareRecovery of FunctionRisk AssessmentRisk FactorsTreatment OutcomeConceptsBariatric surgeryQuality Safety ProgramSurgical careHealthcare ResearchJohns Hopkins Medicine Armstrong InstituteEvidence reviewAvailable evidenceSafety programHospital staySurgery protocolPostoperative phaseSociety guidelinesAnesthetic interventionsAnesthetic componentsArmstrong InstituteAmerican CollegeSurgeryEnhanced recoverySuperior outcomesLiterature searchPatient safetyFacilitate recoveryCareInterventionOutcomesAnesthesia for Spine Surgery
Zorrilla-Vaca A, Grant M, Mirski M. Anesthesia for Spine Surgery. 2019, 189-200. DOI: 10.1007/978-981-13-3387-3_14.Peer-Reviewed Original ResearchSpine surgeryMultimodal analgesic strategyIntraoperative blood lossLumbar spine surgeryLength of stayManagement of anesthesiaPatient-focused approachAnalgesic strategiesHospital stayPostoperative complicationsPostoperative nauseaPostoperative painPostoperative outcomesAnesthetic managementBlood lossAnesthetic techniqueGeneral anesthesiaIntraoperative stabilityPerioperative assessmentOptimal anesthesiaRegional anesthesiaRegional techniquesSurgery programSurgeryAnesthesiaEvidence review conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery: focus on anesthesiology for gynecologic surgery
Grant M, Gibbons M, Ko C, Wick E, Cannesson M, Scott M, Wu C. Evidence review conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery: focus on anesthesiology for gynecologic surgery. Regional Anesthesia & Pain Medicine 2019, 44: 437-446. PMID: 30737316, DOI: 10.1136/rapm-2018-100071.Peer-Reviewed Original ResearchGynecologic surgerySurgical careJohns Hopkins Medicine Armstrong InstituteEvidence reviewEvidence-based process measuresAvailable evidenceAHRQ Safety ProgramSurgical service linesAnesthesia componentsHospital stayPerioperative carePostoperative phaseAnesthetic componentsArmstrong InstituteHastens recoveryAmerican CollegeSafety programSurgerySuperior outcomesPatient safetyLiterature searchHealthcare ResearchFacilitate recoveryCareProcess measures
2018
Barriers to and Facilitators of Implementing Enhanced Recovery Pathways Using an Implementation Framework: A Systematic Review
Stone AB, Yuan CT, Rosen MA, Grant MC, Benishek LE, Hanahan E, Lubomski LH, Ko C, Wick EC. Barriers to and Facilitators of Implementing Enhanced Recovery Pathways Using an Implementation Framework: A Systematic Review. JAMA Surgery 2018, 153: 270-279. PMID: 29344622, DOI: 10.1001/jamasurg.2017.5565.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwayFrontline cliniciansSystematic reviewRecovery pathwaysRural hospital locationHigh-quality studiesFull-text screeningInitial search strategyStandardized extraction formHospital stayPerioperative interventionsTraditional carePatient complexityOuter settingExtraction formIntervention characteristicsCFIR domainsPRISMA statementEvidence reviewMultidisciplinary teamInner settingHospital locationConsolidated FrameworkCommon barriersImplementation research
2016
A Meta-analysis of Intraoperative Ventilation Strategies to Prevent Pulmonary Complications
Yang D, Grant M, Stone A, Wu C, Wick E. A Meta-analysis of Intraoperative Ventilation Strategies to Prevent Pulmonary Complications. Annals Of Surgery 2016, 263: 881-887. PMID: 26720429, DOI: 10.1097/sla.0000000000001443.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureAcute lung injuryPostoperative lung infectionLung infectionLung ventilationLTV ventilationHospital stayHealthy patientsLow tidal volume mechanical ventilationPostoperative acute lung injuryIntermittent recruitment maneuverIntraoperative ventilation strategiesProtective lung ventilationLength of hospitalProtective ventilation strategyEnd-expiratory pressureVolume mechanical ventilationVentilation strategiesAnalysis of trialsPostoperative incidencePulmonary complicationsPulmonary outcomesProtective ventilationLung injuryRecruitment maneuversPatient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection
Page A, Gani F, Crowley K, Lee K, Grant M, Zavadsky T, Hobson D, Wu C, Wick E, Pawlik T. Patient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection. British Journal Of Surgery 2016, 103: 564-571. PMID: 26859713, DOI: 10.1002/bjs.10087.Peer-Reviewed Original ResearchConceptsPost-ERAS groupPerioperative care pathwaysERAS pathwayOpen liver surgeryHospital stayPerioperative outcomesPostoperative complicationsOpioid useLiver surgeryCare pathwayProviders' perceptionsMean pain scoreOpen liver resectionShorter hospital stayImproved perioperative outcomesGroup of patientsCent of providersPerioperative pathwayPain scoresERAS programLiver resectionSurgery pathwayDisease characteristicsHepatic surgeryHospital costs