2016
Retinal Wave Patterns Are Governed by Mutual Excitation among Starburst Amacrine Cells and Drive the Refinement and Maintenance of Visual Circuits
Xu HP, Burbridge TJ, Ye M, Chen M, Ge X, Zhou ZJ, Crair MC. Retinal Wave Patterns Are Governed by Mutual Excitation among Starburst Amacrine Cells and Drive the Refinement and Maintenance of Visual Circuits. Journal Of Neuroscience 2016, 36: 3871-3886. PMID: 27030771, PMCID: PMC4812142, DOI: 10.1523/jneurosci.3549-15.2016.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAge FactorsAmacrine CellsAnimalsAnimals, NewbornCalciumCholera ToxinCholine O-AcetyltransferaseCholinergic AgentsGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsIn Vitro TechniquesMiceMice, TransgenicPatch-Clamp TechniquesReceptors, NicotinicRetinaRetinal Ganglion CellsVesicular Glutamate Transport Protein 1Visual PathwaysConceptsEye-specific segregationVisual circuit developmentStarburst amacrine cellsStage III retinal wavesRetinal ganglion cellsRetinal wavesAmacrine cellsGlutamatergic wavesGanglion cellsSpontaneous activityVisual circuitsStage IICircuit developmentHigher-order visual areasNicotinic acetylcholine receptorsRetinal cell typesMammalian visual systemAcetylcholine receptorsΒ2-nAChRsVisual areasPatterned activityPatterning of activityΒ2 subunitCell typesCells
2014
Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1
Ribic A, Liu X, Crair MC, Biederer T. Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1. The Journal Of Comparative Neurology 2014, 522: 900-920. PMID: 23982969, PMCID: PMC3947154, DOI: 10.1002/cne.23452.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol OxidoreductasesAnalysis of VarianceAnimalsAnimals, NewbornCell Adhesion Molecule-1Cell Adhesion MoleculesCo-Repressor ProteinsDNA-Binding ProteinsElectroretinographyFemaleGene Expression Regulation, DevelopmentalImmunoglobulinsMaleMiceMice, Inbred C57BLMice, KnockoutMicroscopy, ImmunoelectronNerve Tissue ProteinsPhosphoproteinsReceptors, Metabotropic GlutamateRetinaRetinal Rod Photoreceptor CellsSynapsesVesicular Glutamate Transport Protein 1ConceptsCell adhesion molecule-1Adhesion molecule-1Ribbon synapsesKO retinasSynaptic cell adhesion molecule 1Molecule-1Mouse photoreceptor ribbon synapsesInner retinal layersPhotoreceptor ribbon synapsesRod visual pathwayEarly postnatal stagesPlexiform layerKO micePhotoreceptor synapsesSynaptic organizationExcitatory synapsesQuantitative ultrastructural analysisRetinal layersKnockout miceOuter nuclearVisual pathwaySynapse developmentElectroretinogram recordingsPostnatal stagesAdhesion molecules