Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex
Wang BS, Bernardez Sarria MS, An X, He M, Alam NM, Prusky GT, Crair MC, Huang ZJ. Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex. Neuron 2020, 109: 502-515.e7. PMID: 33290732, PMCID: PMC7943176, DOI: 10.1016/j.neuron.2020.11.004.Peer-Reviewed Original ResearchConceptsPrimary visual cortexVisual cortexTranscallosal pathwayVisual fieldDeficient binocular visionGABAergic chandelier cellsBinocular circuitsBinocular visionChandelier cellsRetinal activityTranscallosal projectionsGeniculocortical inputCallosal activityCenter visual fieldBinocular regionCortexMassive apoptosisDevelopmental assemblyCritical periodV1IpsiBlockadePathwayBinocularityMice