2019
Visual Cortex Gains Independence from Peripheral Drive before Eye Opening
Gribizis A, Ge X, Daigle TL, Ackman JB, Zeng H, Lee D, Crair MC. Visual Cortex Gains Independence from Peripheral Drive before Eye Opening. Neuron 2019, 104: 711-723.e3. PMID: 31561919, PMCID: PMC6872942, DOI: 10.1016/j.neuron.2019.08.015.Peer-Reviewed Original ResearchConceptsSuperior colliculusEarly functional developmentSpontaneous neuronal activitySecond postnatal weekPrimary visual cortexPeripheral driveCortex maturesRetinal activityPostnatal weekNeuronal activityDirect projectionsVisual cortexMammalian brainSensory peripheryVisual-spatial perceptionEye openingFunctional developmentPeripheral activityColliculusWeeksDistinct pathwaysPathwayRelative functionV1Thalamus
1997
Silent Synapses during Development of Thalamocortical Inputs
Isaac J, Crair M, Nicoll R, Malenka R. Silent Synapses during Development of Thalamocortical Inputs. Neuron 1997, 18: 269-280. PMID: 9052797, DOI: 10.1016/s0896-6273(00)80267-6.Peer-Reviewed Original ResearchConceptsLong-term potentiationThalamocortical synapsesThalamocortical inputsSilent synapsesFunctional synapsesPostnatal day 8Rat somatosensory cortexActivity-dependent mechanismsActivity-dependent increaseEarly postnatal developmentSomatosensory cortexPostsynaptic activityTopographical projectionDay 8Postnatal developmentSynaptic connectionsSynaptic strengthSynapsesCortexSignificant proportionThalamusEarly developmentPotentiation