Aldosterone-mediated Na/K-ATPase expression is alpha 1 isoform specific in the renal cortical collecting duct.
Welling PA, Caplan M, Sutters M, Giebisch G. Aldosterone-mediated Na/K-ATPase expression is alpha 1 isoform specific in the renal cortical collecting duct. Journal Of Biological Chemistry 1993, 268: 23469-23476. PMID: 8226873, DOI: 10.1016/s0021-9258(19)49486-6.Peer-Reviewed Original ResearchConceptsAlpha 1 formWestern blot analysisMineralocorticoid hormonesAlpha 1 isoformK-ATPase expressionAldosteroneAlpha-subunit isoformsK-ATPase moleculesNa/K-ATPase expressionK-ATPase catalytic subunitPump activityBlot analysisElectrophysiological assaysAlpha isoformAntipeptide antibodiesAttractive hypothesisDifferential regulationIsoform switchSubunit isoformsDuctNa/KIsoformsSodium affinityMolecular basis