1991
Distinct pathways for basolateral targeting of membrane and secretory proteins in polarized epithelial cells.
Boll W, Partin JS, Katz AI, Caplan MJ, Jamieson JD. Distinct pathways for basolateral targeting of membrane and secretory proteins in polarized epithelial cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 8592-8596. PMID: 1656451, PMCID: PMC52555, DOI: 10.1073/pnas.88.19.8592.Peer-Reviewed Original ResearchConceptsCarrier vesiclesMembrane proteinsBasolateral domainSecretory proteinsMadin-Darby canine kidney II cell linePolarized epithelial cellsBasement membrane protein lamininEpithelial cellsBasolateral proteinsBasolateral targetingProtein lamininMicrotubule disruptionDistinct pathwaysMicrotubule depolymerizationProteinDistinct setsCell linesBinding sitesBasolateral secretionIntegrinsVesiclesLamininPathwayMembraneCells
1987
Dependence on pH of polarized sorting of secreted proteins
Caplan M, Stow J, Newman A, Madri J, Anderson H, Farquhar M, Palade G, Jamieson J. Dependence on pH of polarized sorting of secreted proteins. Nature 1987, 329: 632-635. PMID: 2821405, DOI: 10.1038/329632a0.Peer-Reviewed Original ResearchConceptsSecretory proteinsMDCK cellsDifferent protein compositionsBasolateral cell surfacePolarized sortingMembrane proteinsBasolateral domainDefault pathwayPlasma membraneAcidic intracellular compartmentsIntracellular compartmentsProtein compositionMembrane componentsCell surfaceBasement membrane componentsProteinSecrete lamininDistinct setsRenal tubule cellsEpithelial cellsActive sortingBasolateral compartmentCellsSecretory productsSpecific regionsProcessing and Sorting of Proteins Synthesized in the Endoplasmic Reticulum
Caplan M, Rosenzweig S, Jamieson J. Processing and Sorting of Proteins Synthesized in the Endoplasmic Reticulum. 1987, 273-281. DOI: 10.1007/978-1-4613-1943-6_16.Peer-Reviewed Original ResearchIntracellular membrane-bounded compartmentsEndoplasmic reticulumSorting of proteinsRough endoplasmic reticulumMembrane-bounded compartmentsIntracellular digestion processSpecialized functional domainsEukaryotic cellsMembrane proteinsFunctional domainsSecretory proteinsIntracellular compartmentsLysosomal hydrolasesProteinExtracellular spaceMajor classesReticulumCompartmentsBiogenesisCommon setCellsHydrolasesPlasmalemmaDigestion processSorting
1986
Processing and Sorting of Proteins Synthesized in the Endoplasmic Reticulum
Caplan M, Rosenzweig S, Jamieson J. Processing and Sorting of Proteins Synthesized in the Endoplasmic Reticulum. 1986, 273-281. DOI: 10.1007/978-1-4613-2097-5_16.Peer-Reviewed Original ResearchIntracellular membrane-bounded compartmentsEndoplasmic reticulumSorting of proteinsRough endoplasmic reticulumMembrane-bounded compartmentsIntracellular digestion processSpecialized functional domainsEukaryotic cellsMembrane proteinsFunctional domainsSecretory proteinsIntracellular compartmentsLysosomal hydrolasesProteinExtracellular spaceMajor classesReticulumCompartmentsBiogenesisCommon setCellsHydrolasesPlasmalemmaDigestion processSorting