Expression of tetraspanin protein CD63 enhances the PTK‐induced inhibition of ROMK channels
Lin D, Kamsteeg R, Sterling H, Jin Y, Zhang Y, Roos M, Spencer J, Caplan M, Wang W. Expression of tetraspanin protein CD63 enhances the PTK‐induced inhibition of ROMK channels. The FASEB Journal 2007, 21: a1331-a1332. DOI: 10.1096/fasebj.21.6.a1331-d.Peer-Reviewed Original ResearchInhibition of PTKROMK channelsInhibitory effectK currentsHEK293 cellsC-SrcRenal outer medullaProtein tyrosine kinasesRole of CD63Tyrosine phosphorylationOuter medullaDecreased expressionTetraspanin protein CD63CD63Voltage clampElectrode voltage clampInhibitionHerbimycin AOocytesTyrosine kinaseXenopus oocytesPresent studyActivated PKCTetraspanin proteinsCoexpression