The uptake and intracellular fate of PLGA nanoparticles in epithelial cells
Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials 2009, 30: 2790-2798. PMID: 19232712, PMCID: PMC3195413, DOI: 10.1016/j.biomaterials.2009.01.057.Peer-Reviewed Original ResearchConceptsEpithelial cellsCell linesRenal proximal tubulesType of epitheliumParticle/cell ratiosCaco-2 cellsEpithelial cell lineIntracellular fateProximal tubulesRespiratory airwaysCell ratioImmunofluorescence techniqueOK cellsDifferent epithelial cell linesEndoplasmic reticulumConfocal analysisMajor targetConfocal microscopyExtent of uptakeCellsParticle uptakeEarly endosomesCellular uptakePLGA nanoparticlesUptake