1999
Magnetic resonance imaging and neurological recovery in acute spinal cord injury: observations from the National Acute Spinal Cord Injury Study 3
Shepard M, Bracken M. Magnetic resonance imaging and neurological recovery in acute spinal cord injury: observations from the National Acute Spinal Cord Injury Study 3. Spinal Cord 1999, 37: 833-837. PMID: 10602525, DOI: 10.1038/sj.sc.3100927.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingAcute spinal cord injurySpinal cord injuryCord injuryMotor functionResonance imagingSpinal cord injury centerBlind clinical trialInitial neurological examinationInitial clinical examinationLight touch sensationComplete cord injurySpinal cord surgeryMultiple logistic regressionNational InstitutePresence of edemaComplete injuryNeurological recoveryRandomized patientsStudy drugCord edemaNeurological statusCord surgeryNeurological examinationNeurological assessment
1990
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
Bracken M, Shepard M, Collins W, Holford T, Young W, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. New England Journal Of Medicine 1990, 322: 1405-1411. PMID: 2278545, DOI: 10.1056/nejm199005173222001.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryNeurologic recoverySafety of methylprednisoloneSystematic neurological examinationPlacebo-controlled trialHours of injuryMajor morbidityNeurologic outcomeControlled TrialsNeurological examinationIncomplete lesionsMotor functionMethylprednisoloneNaloxonePatientsBody weightSensory functionInjuryPlaceboInfusionBolusEffective remainsTreatmentDose
1978
Classification of the severity of acute spinal cord injury: implications for management
Bracken M, Webb S, Wagner F. Classification of the severity of acute spinal cord injury: implications for management. Spinal Cord 1978, 15: 319-326. PMID: 625431, DOI: 10.1038/sc.1977.48.Peer-Reviewed Original ResearchConceptsSpinal cord injuryAcute spinal cord injuryCord injuryMotor functionBrown-Sequard syndromeMotor function scalesPoor motor functionComprehensive neurological examinationDifferent therapeutic modalitiesSevere motor impairmentAcute hospitalisationCord lesionsNeurological examinationFracture dislocationSensory lossProspective studyEmergency departmentHigh prevalenceTherapeutic modalitiesMotor impairmentSensory functionPatientsFunction scaleOlder ageInjury