Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. PLOS ONE 2013, 8: e63773. PMID: 23691095, PMCID: PMC3656905, DOI: 10.1371/journal.pone.0063773.Peer-Reviewed Original ResearchMeSH KeywordsHumansMelatoninPubMedRegression AnalysisSleep Wake DisordersTime FactorsTreatment OutcomeConceptsPrimary sleep disordersTotal sleep timeOverall sleep qualityEffect of melatoninSleep disordersSleep qualitySleep latencySleep timeBenign side effect profilePlacebo-controlled trialSide effect profileEfficacy of melatoninTreatment of insomniaSleep onset latencyInfluence of doseDuration of melatoninMelatonin dosePrimary outcomeAbsolute benefitMelatonin usePharmacological treatmentSignificant efficacyNineteen studiesSleep parametersOnset latency