2019
Trim the fat: the role of omega-3 fatty acids in psychopharmacology
Nasir M, Bloch MH. Trim the fat: the role of omega-3 fatty acids in psychopharmacology. Therapeutic Advances In Psychopharmacology 2019, 9: 2045125319869791. PMID: 31489174, PMCID: PMC6713969, DOI: 10.1177/2045125319869791.Peer-Reviewed Original ResearchPost-traumatic stress disorderDepressive disorderAmerican Psychiatric AssociationFindings of RCTsRecent negative studiesSide effect profileFatty acid supplementationFatty acidsRandomized-controlled trialEvidence of efficacySubstantial methodological shortcomingsEvidence-based treatmentsImpulse control disordersIncomplete blindingHeterogeneous sample populationsBipolar maniaTreatment guidelinesCurrent guidelinesCardiovascular diseaseAcid supplementationNegative studiesPatient complianceUnipolar depressionIneffective treatmentPsychotic disorders
2018
Supplementation with polyunsaturated fatty acids (PUFAs) in the management of attention deficit hyperactivity disorder (ADHD)
Banaschewski T, Belsham B, Bloch MH, Ferrin M, Johnson M, Kustow J, Robinson S, Zuddas A. Supplementation with polyunsaturated fatty acids (PUFAs) in the management of attention deficit hyperactivity disorder (ADHD). Nutrition And Health 2018, 24: 279-284. PMID: 29921155, PMCID: PMC6291899, DOI: 10.1177/0260106018772170.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderPUFA supplementationDeficit hyperactivity disorderManagement of ADHDFurther high-quality researchHyperactivity disorderPossible side effectsSmall beneficial effectRobust evidence baseChild attention-deficit hyperactivity disorderFatty acidsFrontline treatmentHigh-quality researchCurrent evidenceSide effectsPsychosocial interventionsTreatment approachesPanel consensusPatientsBeneficial effectsEvidence baseSupplementationInternational expertsDisordersAdultsEditorial: Can omega‐3 fatty acids improve executive functioning? Will this reduce ADHD and depression?
Artukoglu BB, Bloch MH. Editorial: Can omega‐3 fatty acids improve executive functioning? Will this reduce ADHD and depression? Journal Of Child Psychology And Psychiatry 2018, 59: 615-617. PMID: 29808491, DOI: 10.1111/jcpp.12932.Peer-Reviewed Original Research
2012
Response to critiques on ‘Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis’
Bloch M, Hannestad J. Response to critiques on ‘Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis’. Molecular Psychiatry 2012, 17: 1163-1167. DOI: 10.1038/mp.2012.116.Peer-Reviewed Original Research
2011
Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis
Bloch MH, Qawasmi A. Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 991-1000. PMID: 21961774, PMCID: PMC3625948, DOI: 10.1016/j.jaac.2011.06.008.Peer-Reviewed Original ResearchConceptsFatty acid supplementationAttention-deficit/hyperactivity disorderAcid supplementationOmega-3 Fatty Acid SupplementationTreatment of ADHDRandomized placebo-controlled trialBenign side effect profilePlacebo-controlled trialSide effect profilePrimary outcome measurementAnti-inflammatory propertiesTreatment of childrenCell membrane fluidityEffect of dosingAvailable pharmacotherapiesFatty acidsModest efficacyPharmacologic interventionsHyperactivity disorder symptomatologyOutcome measurementsDopamine neurotransmissionAcid doseHigh dosesPsychopharmacologic optionsMeta-Analysis