2014
Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
Ferracioli-Oda E, Qawasmi A, Bloch M. Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. FOCUS The Journal Of Lifelong Learning In Psychiatry 2014, 12: 73-79. DOI: 10.1176/appi.focus.12.1.73.Peer-Reviewed Original ResearchPrimary sleep disordersTotal sleep timeOverall sleep qualityEffect of melatoninSleep disordersSleep qualitySleep latencySleep timeBenign side effect profilePlacebo-controlled trialSide effect profileEfficacy of melatoninTreatment of insomniaSleep onset latencyInfluence of doseDuration of melatoninMelatonin dosePrimary outcomeAbsolute benefitMelatonin usePharmacological treatmentSignificant efficacyNineteen studiesSleep parametersOnset latency
2013
Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. PLOS ONE 2013, 8: e63773. PMID: 23691095, PMCID: PMC3656905, DOI: 10.1371/journal.pone.0063773.Peer-Reviewed Original ResearchConceptsPrimary sleep disordersTotal sleep timeOverall sleep qualityEffect of melatoninSleep disordersSleep qualitySleep latencySleep timeBenign side effect profilePlacebo-controlled trialSide effect profileEfficacy of melatoninTreatment of insomniaSleep onset latencyInfluence of doseDuration of melatoninMelatonin dosePrimary outcomeAbsolute benefitMelatonin usePharmacological treatmentSignificant efficacyNineteen studiesSleep parametersOnset latency
2011
Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis
Bloch MH, Qawasmi A. Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 991-1000. PMID: 21961774, PMCID: PMC3625948, DOI: 10.1016/j.jaac.2011.06.008.Peer-Reviewed Original ResearchConceptsFatty acid supplementationAttention-deficit/hyperactivity disorderAcid supplementationOmega-3 Fatty Acid SupplementationTreatment of ADHDRandomized placebo-controlled trialBenign side effect profilePlacebo-controlled trialSide effect profilePrimary outcome measurementAnti-inflammatory propertiesTreatment of childrenCell membrane fluidityEffect of dosingAvailable pharmacotherapiesFatty acidsModest efficacyPharmacologic interventionsHyperactivity disorder symptomatologyOutcome measurementsDopamine neurotransmissionAcid doseHigh dosesPsychopharmacologic optionsMeta-Analysis