2020
What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original ResearchRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean durationCranial Fossa Development in Differing Subtypes of Crouzon Syndrome.
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Cranial Fossa Development in Differing Subtypes of Crouzon Syndrome. Journal Of Craniofacial Surgery 2020, 31: 673-677. PMID: 32049910, DOI: 10.1097/scs.0000000000006181.Peer-Reviewed Original ResearchCranial Fossa, PosteriorCraniofacial DysostosisCraniosynostosesFemaleHumansMaleTomography, X-Ray ComputedClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologies
2019
Cranial Fossa Volume in Differing Subtypes of Apert Syndrome.
Lu X, Forte AJ, Wilson A, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Cranial Fossa Volume in Differing Subtypes of Apert Syndrome. Journal Of Craniofacial Surgery 2019, 30: 2345-2349. PMID: 31609946, DOI: 10.1097/scs.0000000000005785.Peer-Reviewed Original ResearchWhat Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis?
Lu X, Chen G, Forte AJ, Cabrejo R, Singh A, Kyle G, Steinbacher DM, Alperovich M, Alonso N, Persing JA. What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis? Journal Of Craniofacial Surgery 2019, 30: 1671-1675. PMID: 30950948, DOI: 10.1097/scs.0000000000005396.Peer-Reviewed Original ResearchMeSH KeywordsCephalometryChildChild, PreschoolCranial SuturesCraniofacial DysostosisCraniosynostosesFemaleHumansMalePlastic Surgery ProceduresSkullTomography, X-Ray ComputedConceptsMiddle cranial fossaAnterior cranial fossaCranial fossaPosterior cranial fossaSquamosal synostosisFossa volumeCrouzon syndromeSquamosal suture synostosisComputed tomography scanCranial volumeNonsyndromic craniosynostosis patientsVolume reductionSevere volume reductionTomography scanNormal controlsMorphologic effectsCraniosynostosis patientsFossaPremature closureSyndromic conditionsSuture synostosisSyndromic synostosisFrankfort horizontal planeSynostosisThree-dimensional cephalometryAnalysis of Airway and Midface in Crouzon Syndromes
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Analysis of Airway and Midface in Crouzon Syndromes. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30633021, DOI: 10.1097/sap.0000000000001740.Peer-Reviewed Original ResearchConceptsPharyngeal airway volumeComputed tomography scanAirway volumeControl subjectsTomography scanCrouzon syndromeAge-matched control subjectsAnalysis of airwaysSevere respiratory impairmentNasal airway volumePosterior pharyngeal wallEarly mixed dentitionCrouzon groupSurgical interventionRespiratory impairmentUpper airwaySoft tissue measurementsPharyngeal wallPosterior tongueMixed dentitionAirwayPatientsSyndromeVolumetric assessmentT-testAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original ResearchTemporal Evaluation of Craniofacial Relationships in Apert Syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Gabrick K, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Temporal Evaluation of Craniofacial Relationships in Apert Syndrome. Journal Of Craniofacial Surgery 2019, 30: 317-325. PMID: 30358751, DOI: 10.1097/scs.0000000000004836.Peer-Reviewed Original ResearchMeSH KeywordsAcrocephalosyndactyliaCephalometryChild, PreschoolFaceHumansInfantSkullTomography, X-Ray ComputedConceptsYears of ageApert syndromeNasal spineComputed tomography scanMaxillary planeAnterior nasal spineMonths of ageApert syndrome patientsPosterior nasal spineSella-nasion planeTomography scanSyndrome patientsAge subgroupsAnatomic relationshipsSyndromeFacial deformityAngulation changeFrankfort horizontal planeCranial base lengthMonthsIntracellular regulatory mechanismsCraniofacial malformationsAgeDeformityMaterialize softwareSpatial and temporal changes of midface in Apert’s syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Spatial and temporal changes of midface in Apert’s syndrome. Journal Of Plastic Surgery And Hand Surgery 2019, 53: 130-137. PMID: 30782083, DOI: 10.1080/2000656x.2018.1541324.Peer-Reviewed Original Research
2018
Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnthropometryChildChild, PreschoolCraniofacial DysostosisFemaleHumansInfantInfant, NewbornMaleMaxillaMiddle AgedOrbitTomography, X-Ray ComputedZygomaConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise softwareAnterior convex lateral orbital wall: distinctive morphology in Apert syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Anterior convex lateral orbital wall: distinctive morphology in Apert syndrome. British Journal Of Oral And Maxillofacial Surgery 2018, 56: 864-869. PMID: 30337164, DOI: 10.1016/j.bjoms.2018.09.011.Peer-Reviewed Original ResearchNormal angulation of skull base in Apert syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Normal angulation of skull base in Apert syndrome. Journal Of Cranio-Maxillofacial Surgery 2018, 46: 2042-2051. PMID: 30391086, DOI: 10.1016/j.jcms.2018.09.026.Peer-Reviewed Original ResearchMeSH KeywordsAcrocephalosyndactyliaChildChild, PreschoolFemaleHumansInfantLongitudinal StudiesMaleSkull BaseTomography, X-Ray ComputedConceptsAnterior cranial baseApert syndromeCranial base lengthSkull baseSevere craniofacial deformitiesPosterior cranial base lengthYears of ageMonths of ageUnoperated patientsCT scanAnterior cranial base lengthCranial base angleLate infancySyndromeAge rangeCraniofacial deformitiesCranial baseDeformityAdditive effectSkull vaultMonthsAngulationSignificant changesAgeBase length
2017
Minor Suture Fusion in Syndromic Craniosynostosis
Runyan CM, Xu M D W, Alperovich M, Massie M D J, Paek G, Cohen BA, Staffenberg DA, Flores RL, Taylor JA. Minor Suture Fusion in Syndromic Craniosynostosis. Plastic & Reconstructive Surgery 2017, 140: 434e-445e. PMID: 28574949, DOI: 10.1097/prs.0000000000003586.Peer-Reviewed Original ResearchMeSH KeywordsCranial SuturesCraniofacial DysostosisCraniosynostosesFemaleHumansInfantIntracranial PressureMaleReceptor, Fibroblast Growth Factor, Type 2Tomography, X-Ray ComputedConceptsSuture synostosisCLINICAL QUESTION/LEVELSyndromic craniosynostosisSuture fusionMost patientsTomographic scanSyndromic patientsPatientsPosterior branchSkull baseCraniofacial dysostosisHead shape anomaliesSuture involvementInfantsFGFR2 mutationsSynostosisMidface abnormalitiesCraniofacial surgeonsCraniosynostosisCraniofacial dysostosis syndromesSelect groupCalvarial suturesScansShape anomaliesPatent calvarial sutures
2016
Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair
Alperovich M, Frey JD, Potts MB, Riina HA, Staffenberg DA. Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair. Journal Of Craniofacial Surgery 2016, 27: 1077-1079. PMID: 27192638, DOI: 10.1097/scs.0000000000002643.Peer-Reviewed Original ResearchConceptsCraniofacial principlesNeurosurgical exposureCraniofacial surgeonsZygomaticomaxillary complex fracturesSuperior cosmetic resultsAnterior skull baseRisk of injuryAneurysm repairNerve transectionCosmetic resultsFacial nerveEyebrow incisionPeriorbital surgeryFrontal branchSkull baseConspicuous scarringTranspalpebral approachComplex fracturesNeurosurgical literatureSeries experienceSurgeonsCraniofacial surgerySurgeryCraniotomyExposure
2015
Is Craniosynostosis Repair Keeping Up With the Times? Results From the Largest National Survey on Craniosynostosis
Alperovich M, Vyas RM, Staffenberg DA. Is Craniosynostosis Repair Keeping Up With the Times? Results From the Largest National Survey on Craniosynostosis. Journal Of Craniofacial Surgery 2015, 26: 1909-1913. PMID: 26244471, DOI: 10.1097/scs.0000000000001300.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnti-Bacterial AgentsBlood TransfusionClinical CompetenceCraniosynostosesCritical CareDrainageHumansInfantIntraoperative ComplicationsMonitoring, IntraoperativeOperative TimePatient Care TeamPerioperative CarePlastic Surgery ProceduresPostoperative CarePractice Patterns, Physicians'Tomography, X-Ray ComputedUnited StatesConceptsPractice patternsIntensive postoperative surveillanceOverall transfusion rateLong-term antibioticsExtremes of ageCurrent practice patternsIntensive care unitShorter operative timeEvidence-based guidelinesSurgical practice patternsYears of ageNational surveyTransfusion ratePerioperative managementPostoperative surveillanceBlood transfusionOpen repairCare unitOperative timePreoperative imagingTomography scanCraniosynostosis repairSurgeon experienceExtended courseClinical practice