2020
SMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis.
Wu RT, Timberlake AT, Abraham PF, Gabrick KS, Lu X, Peck CJ, Sawh-Martinez RF, Steinbacher DM, Alperovich MA, Persing JA. SMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis. Plastic & Reconstructive Surgery 2020, 145: 117e-125e. PMID: 31592950, DOI: 10.1097/prs.0000000000006319.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesChildChild BehaviorChild DevelopmentChild, PreschoolCraniosynostosesCraniotomyDevelopmental DisabilitiesDouble-Blind MethodFemaleFollow-Up StudiesHumansInfantIntelligence TestsLoss of Function MutationMalePlastic Surgery ProceduresProspective StudiesSkullSmad6 ProteinTreatment OutcomeImpact of Insurance Payer on Type of Breast Reconstruction Performed.
Chouairi F, Mets EJ, Gabrick KS, Dinis J, Avraham T, Alperovich M. Impact of Insurance Payer on Type of Breast Reconstruction Performed. Plastic & Reconstructive Surgery 2020, 145: 1e-8e. PMID: 31881596, DOI: 10.1097/prs.0000000000006315.Peer-Reviewed Original ResearchConceptsBreast reconstructionBreast reconstruction modalityAcademic medical centerOdds ratioMedical CenterMuscle-sparing transverse rectus abdominis myocutaneous flapPerforator flapTissue expander/implant breast reconstructionExpander/implant breast reconstructionMicrovascular autologous breast reconstructionTransverse rectus abdominis myocutaneous flapPerforator flap breast reconstructionIncome quartileCLINICAL QUESTION/LEVELReconstruction modalitiesSame academic medical centerRectus abdominis myocutaneous flapAutologous breast reconstructionFlap breast reconstructionImplant breast reconstructionHighest income quartileLowest income quartileInsurance typeMicrovascular reconstructionChi-square analysis
2019
Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction
Chouairi F, Gabrick KS, Avraham T, Markov NP, Alperovich M. Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction. Plastic & Reconstructive Surgery 2019, Publish Ahead of Print: &na;. PMID: 30730496, DOI: 10.1097/prs.0000000000005423.Peer-Reviewed Original ResearchConceptsMastectomy flap necrosisTwo-stage implant breast reconstructionImplant breast reconstructionFlap necrosisBreast reconstructionHigh riskProphylactic mastectomyTherapeutic mastectomyMastectomy indicationExact testTissue expander breast reconstructionCLINICAL QUESTION/LEVELYale-New Haven HospitalPermanent implant reconstructionExpander breast reconstructionTimes higher riskFisher's exact testNew Haven HospitalSignificant differencesBreast reconstruction proceduresBinary logistic regressionReconstructive complicationsBreast groupPerioperative complicationsComplication rate
2018
Evolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy
Frey JD, Stranix JT, Chiodo MV, Alperovich M, Ahn CY, Allen RJ, Choi M, Karp NS, Levine JP. Evolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy. Plastic & Reconstructive Surgery 2018, 141: 1086-1093. PMID: 29659449, DOI: 10.1097/prs.0000000000004271.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast NeoplasmsFemaleFree Tissue FlapsHumansMammaplastyMastectomy, SubcutaneousMiddle AgedNipplesPatient SatisfactionPerforator FlapPostoperative CarePostoperative ComplicationsReoperationRetrospective StudiesTransplantation, AutologousTreatment OutcomeUltrasonography, DopplerConceptsNipple-sparing mastectomyFree flap reconstructionSkin paddleFlap reconstructionAutologous reconstructionRevision proceduresMuscle-sparing transverse rectus abdominis myocutaneous flapFree flap autologous breast reconstructionAutologous free flap reconstructionTransverse rectus abdominis myocutaneous flapGreater body mass indexCLINICAL QUESTION/LEVELPercentage of flapsProfunda artery perforatorRectus abdominis myocutaneous flapAutologous breast reconstructionBody mass indexInferior epigastric perforatorGreater mean numberMass indexFlap weightMastectomy weightComparing outcomesBreast reconstructionMastectomy reconstruction
2017
Minor Suture Fusion in Syndromic Craniosynostosis
Runyan CM, Xu M D W, Alperovich M, Massie M D J, Paek G, Cohen BA, Staffenberg DA, Flores RL, Taylor JA. Minor Suture Fusion in Syndromic Craniosynostosis. Plastic & Reconstructive Surgery 2017, 140: 434e-445e. PMID: 28574949, DOI: 10.1097/prs.0000000000003586.Peer-Reviewed Original ResearchConceptsSuture synostosisCLINICAL QUESTION/LEVELSyndromic craniosynostosisSuture fusionMost patientsTomographic scanSyndromic patientsPatientsPosterior branchSkull baseCraniofacial dysostosisHead shape anomaliesSuture involvementInfantsFGFR2 mutationsSynostosisMidface abnormalitiesCraniofacial surgeonsCraniosynostosisCraniofacial dysostosis syndromesSelect groupCalvarial suturesScansShape anomaliesPatent calvarial sutures
2016
“Breast in a Day”
Choi M, Frey JD, Alperovich M, Levine JP, Karp NS. “Breast in a Day”. Plastic & Reconstructive Surgery 2016, 138: 184e-191e. PMID: 27465178, DOI: 10.1097/prs.0000000000002333.Peer-Reviewed Original ResearchConceptsPermanent implant reconstructionNipple-sparing mastectomyMastectomy flap necrosisImplant reconstructionAcellular dermal matrixComplication rateFlap necrosisMajor mastectomy flap necrosisMinor mastectomy flap necrosisDermal matrixImplant sizeCLINICAL QUESTION/LEVELPercent of reconstructionsCommon major complicationPrior radiation therapyGreater complication rateLow complication rateNipple-sparing mastectomiesBody mass indexCommon minor complicationAverage implant sizeMajority of implantsOverall complicationsNipple necrosisMinor complications
2013
Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy
Alperovich M, Tanna N, Samra F, Blechman KM, Shapiro RL, Guth AA, Axelrod DM, Choi M, Karp NS. Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy. Plastic & Reconstructive Surgery 2013, 131: 962-967. PMID: 23629078, DOI: 10.1097/prs.0b013e3182865ad2.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyAuthors' institutionMean body mass indexCLINICAL QUESTION/LEVELMastectomy flap necrosisSubset of patientsNipple-sparing mastectomiesBody mass indexBreast cancer recurrenceLatissimus dorsi flapPresence of cancerNipple-areola complexMass indexProphylactic indicationsFlap necrosisMean agePatient populationBiopsy resultsMastectomy patientsTherapeutic resectionCancer recurrenceNipple viabilityReconstructive outcomesMastectomyReduction mammaplastyMicrosurgical Breast Reconstruction for Nipple-Sparing Mastectomy
Tanna N, Broer PN, Weichman KE, Alperovich M, Ahn CY, Allen RJ, Choi M, Karp NS, Saadeh PB, Levine JP. Microsurgical Breast Reconstruction for Nipple-Sparing Mastectomy. Plastic & Reconstructive Surgery 2013, 131: 139e-147e. PMID: 23358009, DOI: 10.1097/prs.0b013e3182789b51.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyMicrosurgical breast reconstructionBreast reconstructionNipple necrosisMastectomy skin flap necrosisFree flap breast reconstructionNew York University Medical CenterCLINICAL QUESTION/LEVELSuperior gluteal artery perforator flapThorough preoperative evaluationGluteal artery perforator flapImmediate breast reconstructionLow complication rateNipple-sparing mastectomiesProfunda artery perforatorSkin flap necrosisBody mass indexFlap breast reconstructionMastectomy specimen weightBreast cancer historyHigh patient satisfactionMajority of flapsChoice of incisionArtery perforator flapMastectomy skin flaps