2013
Different virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves
Park J, Kim H, Matthijnssens J, Alfajaro M, Kim D, Son K, Kwon H, Hosmillo M, Ryu E, Kim J, Cena R, Lee J, Kang M, Park S, Cho K. Different virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves. Veterinary Research 2013, 44: 88. PMID: 24083947, PMCID: PMC3851489, DOI: 10.1186/1297-9716-44-88.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCattleCattle DiseasesDiarrheaMolecular Sequence DataPhylogenyPolymorphism, GeneticReverse Transcriptase Polymerase Chain ReactionRotavirusRotavirus InfectionsSequence AlignmentSequence Analysis, DNASwineSwine DiseasesVirulenceConceptsHistopathological changesSmall intestineGroup A rotavirusesDirect interspecies transmissionGenotype constellationCritical molecular determinantsFull-length sequencing analysisA rotavirusesBovine rotavirusVP1-VP4Pathological phenotypesDifferent virulencePigletsDiarrheaInterspecies transmissionAmino acid mutationsRotavirusCalvesIntestineSpecific mutationsTropismMolecular determinantsSequencing analysisUntranslated regionPorcine
2012
Pathogenicity characterization of a bovine triple reassortant rotavirus in calves and piglets
Kim H, Park J, Alfajaro M, Kim D, Hosmillo M, Son K, Lee J, Bae Y, Park S, Kang M, Cho K. Pathogenicity characterization of a bovine triple reassortant rotavirus in calves and piglets. Veterinary Microbiology 2012, 159: 11-22. PMID: 22465801, DOI: 10.1016/j.vetmic.2012.03.017.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, ViralCattleCattle DiseasesDiarrheaFecesGenotypeIntestinesReassortant VirusesReverse Transcriptase Polymerase Chain ReactionRNA, ViralRotavirusRotavirus InfectionsSwineSwine DiseasesConceptsExtra-intestinal organsMesenteric lymph nodesCross-species pathogenicityReassortant rotavirusesLymph nodesIntestinal pathologyPersistent severe diarrheaSevere intestinal pathologyExtra-intestinal infectionsDiarrhea fecal samplesReal-time RT-PCRGreen real-time RT-PCRSYBR Green real-time RT-PCRSevere diarrheaCerebrospinal fluidChoroid plexusViral replicationRotavirusRT-PCRViral RNAFecal samplesPigletsDiarrheaPublic healthPathology
2010
Development of universal SYBR Green real-time RT-PCR for the rapid detection and quantitation of bovine and porcine toroviruses
Hosmillo M, Jeong Y, Kim H, Collantes T, Alfajaro M, Park J, Kim H, Kwon H, Park S, Kang M, Park S, Cho K. Development of universal SYBR Green real-time RT-PCR for the rapid detection and quantitation of bovine and porcine toroviruses. Journal Of Virological Methods 2010, 168: 212-217. PMID: 20558206, PMCID: PMC7112831, DOI: 10.1016/j.jviromet.2010.06.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBenzothiazolesCattleDiaminesDiarrheaDNA PrimersFecesFluorescent DyesMolecular Sequence DataOrganic ChemicalsQuinolinesReverse Transcriptase Polymerase Chain ReactionRNA, ViralSensitivity and SpecificitySequence Analysis, DNAStaining and LabelingSwineTorovirusTorovirus Infections