2021
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Cell 2021, 184: 2394-2411.e16. PMID: 33743211, PMCID: PMC7951565, DOI: 10.1016/j.cell.2021.03.012.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 RNASARS-CoV-2Virus-induced cell deathHost protein interactionsRNA-binding proteinActive infectionRNA virusesHost-virus interfaceGlobal mortalityTherapeutic benefitCRISPR screensAntiviral factorsProtein interactionsAntiviral activityViral specificityHost pathwaysFunctional RNA-binding proteinsFunctional connectionsRNA-centric approachesCell deathHost proteinsVirusFunctional interrogationRNAComprehensive catalog
2016
Whole genomic characterization of Korean porcine G8P[7] reassortant rotaviruses
Park J, Park S, Woo N, Kim D, Seo J, Alfajaro M, Kim J, Soliman M, Baek Y, Cho E, Kwon J, Choi J, Kang M, Matthijnssens J, Cho K. Whole genomic characterization of Korean porcine G8P[7] reassortant rotaviruses. Archives Of Virology 2016, 161: 2835-2841. PMID: 27393603, DOI: 10.1007/s00705-016-2945-1.Peer-Reviewed Original Research
2011
Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea
Park S, Matthijnssens J, Saif L, Kim H, Park J, Alfajaro M, Kim D, Son K, Yang D, Hyun B, Kang M, Cho K. Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea. Veterinary Microbiology 2011, 152: 55-66. PMID: 21592683, DOI: 10.1016/j.vetmic.2011.04.015.Peer-Reviewed Original ResearchConceptsGenotype constellationT1-E1-H1 genotypesH1 genotype constellationFull-length ORFDetailed phylogenetic analysisGroup A rotavirusesC1-M2Phylogenetic analysisComplete genomeN2-T6Genome constellationM2-A3VP1-4I5-R1Bovine group A rotavirusesHeterologous speciesI2-R2A1-N1ReassortmentG8 genotypeSingle strainReassortant strainsGenotypesStrainsGenome