Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†
Rood KM, Buhimschi CS, Zhao G, Oliver EA, Summerfield T, Bahtiyar MO, Buhimschi IA. Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†. Biology Of Reproduction 2018, 100: 773-782. PMID: 30277495, PMCID: PMC6437262, DOI: 10.1093/biolre/ioy216.Peer-Reviewed Original ResearchConceptsIntra-amniotic infection/inflammationPreterm prelabor ruptureFetal membranesAmniotic fluidTNX expressionPrelabor ruptureInfection/inflammationLung maturity testingMembrane statusSpontaneous PPROMPregnancy complicationsNormal outcomeTherapeutic targetGenetic karyotypingReproductive tissuesPPROMMRNA expressionMaturity testingPregnancyWestern blottingMRNA levelsQRT-PCRExtracellular matrix proteinsCervixInflammationA Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability
Kohari K, Mehlhaff K, Merriam A, Abdel-Razeq S, Grechukhina O, Leon-Martinez D, Bahtiyar MO. A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability. American Journal Of Perinatology Reports 2018, 08: e180-e183. PMID: 30250757, PMCID: PMC6138466, DOI: 10.1055/s-0038-1669964.Peer-Reviewed Original ResearchLimit of viabilityIntra-amniotic infectionSerial transabdominal amnioinfusionsIntra-amniotic infusionSerial amnioinfusionsMaternal morbidityPlacental abruptionPreterm laborTransabdominal amnioinfusionPrelabor rupturePulmonary hypoplasiaPremature rupturePersistent oligohydramniosNormal salineNeonatal survivalLatency periodClinical scenariosAdditional riskSignificant riskAmnioinfusionRiskFetusesInfectionImmediate riskRupture