2019
Antipsychotic Exposure in Pregnancy and the Risk of Gestational Diabetes: A Systematic Review and Meta-analysis
Kucukgoncu S, Guloksuz S, Celik K, Bahtiyar MO, Luykx JJ, Rutten BPF, Tek C. Antipsychotic Exposure in Pregnancy and the Risk of Gestational Diabetes: A Systematic Review and Meta-analysis. Schizophrenia Bulletin 2019, 46: 311-318. PMID: 31167033, PMCID: PMC7442324, DOI: 10.1093/schbul/sbz058.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusAntipsychotic exposureRisk ratioGDM riskHealthy controlsRisk of GDMControl groupSystematic reviewRisk of GestationalModifiable risk factorsConfidence intervalsCumulative risk ratioHealthy control groupSystematic literature searchLifestyle modificationDiabetes mellitusPrimary outcomeGestational ageAntipsychotic usePregnant womenRisk factorsStudy qualityExposure groupMeta-AnalysisPregnancy monitoring
2015
Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis
Dulay AT, Buhimschi IA, Zhao G, Bahtiyar MO, Thung SF, Cackovic M, Buhimschi CS. Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis. Cytokine 2015, 76: 236-243. PMID: 25957466, PMCID: PMC4824401, DOI: 10.1016/j.cyto.2015.04.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmniocentesisAmniotic FluidAsymptomatic InfectionsBiomarkersCalcitoninCalcitonin Gene-Related PeptideChorioamnionitisC-Reactive ProteinFemaleFetal BloodFetal Membranes, Premature RuptureHumansInfant, NewbornInterleukin-6Obstetric Labor, PrematurePlacentaPregnancyPregnancy Complications, InfectiousPremature BirthProtein PrecursorsSystemic Inflammatory Response SyndromeConceptsIntra-amniotic infectionC-reactive proteinSubclinical intra-amniotic infectionIL-6Blood IL-6 levelsBlood IL-6Maternal blood levelsSystemic inflammatory responseIL-6 levelsNon-invasive biomarkersSubgroup of casesChorioamnionitis groupHistological chorioamnionitisInflammatory markersPreterm laborCRP levelsInflammatory biomarkersMaternal serumPlacental pathologyAcute phasePregnant womenBlood levelsSubclinical phaseInterleukin-6Cord blood
2011
Ultrasonographic Evaluation of Myometrial Thickness and Prediction of a Successful External Cephalic Version
Buhimschi CS, Buhimschi IA, Wehrum MJ, Molaskey-Jones S, Sfakianaki AK, Pettker CM, Thung S, Campbell KH, Dulay AT, Funai EF, Bahtiyar MO. Ultrasonographic Evaluation of Myometrial Thickness and Prediction of a Successful External Cephalic Version. Obstetrics And Gynecology 2011, 118: 913-920. PMID: 21934456, DOI: 10.1097/aog.0b013e31822e63fe.Peer-Reviewed Original ResearchConceptsAmniotic fluid indexExternal cephalic versionFundal myometrial thicknessSuccessful external cephalic versionMyometrial thicknessCephalic versionFluid indexHigher amniotic fluid indexAbdominal ultrasonographic scansFetal spine positionConsecutive pregnant womenAbsolute risk reductionBody mass indexExternal cephalic version successStrong independent predictorAbdominal wall thicknessMultivariate regression analysisPlacental thicknessBreech presentationIndependent predictorsFetal weightMass indexPregnant womenUltrasonographic evaluationBirth weightAccreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast
Wehrum MJ, Buhimschi IA, Salafia C, Thung S, Bahtiyar MO, Werner EF, Campbell KH, Laky C, Sfakianaki AK, Zhao G, Funai EF, Buhimschi CS. Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast. American Journal Of Obstetrics And Gynecology 2011, 204: 411.e1-411.e11. PMID: 21316642, PMCID: PMC3136625, DOI: 10.1016/j.ajog.2010.12.027.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorComplete placenta previaPlacenta previaEndothelial growth factorCytokeratin 7Growth factorExtravillous trophoblastsSystemic vascular endothelial growth factorMesenchymal transitionFree vascular endothelial growth factorInterstitial extravillous trophoblastsMesenchymal transition featuresPlacental growth factorAngiogenic factor profilesExpression of vimentinInvasive extravillous trophoblastsUncomplicated pregnanciesMyometrial invasionPregnant womenPreviaInvasive trophoblastFactor profileHistological specimensInvasive placentationSerum samples
2006
Prior cesarean delivery is not associated with an increased risk of stillbirth in a subsequent pregnancy: Analysis of U.S. perinatal mortality data, 1995-1997
Bahtiyar MO, Julien S, Robinson JN, Lumey L, Zybert P, Copel JA, Lockwood CJ, Norwitz ER. Prior cesarean delivery is not associated with an increased risk of stillbirth in a subsequent pregnancy: Analysis of U.S. perinatal mortality data, 1995-1997. American Journal Of Obstetrics And Gynecology 2006, 195: 1373-1378. PMID: 16677588, DOI: 10.1016/j.ajog.2006.02.051.Peer-Reviewed Original ResearchConceptsPrior cesarean deliveryRisk of stillbirthCesarean deliverySubsequent pregnancyPerinatal mortality dataMedical conditionsDemise rateUnexplained intrauterine fetal demiseMortality dataIntrauterine fetal demiseMaternal medical conditionsSingleton term pregnanciesFetal congenital abnormalitiesCesarean delivery rateCross-sectional studySingleton pregnanciesTerm pregnancyFetal demisePrior deliveryPregnant womenMaternal ageCongenital anomaliesStudy groupHaenszel methodCongenital abnormalities