2016
Evidence for participation of neutrophil gelatinase‐associated lipocalin/matrix metalloproteinase‐9 (NGAL•MMP‐9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth
Rood KM, Buhimschi IA, Rodewald Millen K, Bahtiyar MO, Thung S, Summerfield T, Zhao G, Ackerman W, Shellhaas C, Samuels P, Buhimschi CS. Evidence for participation of neutrophil gelatinase‐associated lipocalin/matrix metalloproteinase‐9 (NGAL•MMP‐9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth. American Journal Of Reproductive Immunology 2016, 76: 108-117. PMID: 27251223, PMCID: PMC4942349, DOI: 10.1111/aji.12523.Peer-Reviewed Original ResearchConceptsIntra-amniotic infection/inflammationNeutrophil gelatinase-associated lipocalinMatrix metalloproteinase-9Preterm birthNGAL mRNA expressionGelatinase-associated lipocalinNormal pregnancy outcomeAmniotic fluid levelsInfection/inflammationPlacental villous trophoblastNGAL levelsPregnancy outcomesInflammatory conditionsInflammatory responseMetalloproteinase-9Villous trophoblastFluid levelsInnate immunityCollagenolytic effectMRNA expressionGelatinolytic activityPregnancyHost-microbe interactionsQRT-PCRAmniochorion
2015
Amniotic Fluid Soluble Myeloid Differentiation‐2 (sMD‐2) as Regulator of Intra‐amniotic Inflammation in Infection‐induced Preterm Birth
Dulay AT, Buhimschi CS, Zhao G, Oliver EA, Abdel-Razeq SS, Shook LL, Bahtiyar MO, Buhimschi IA. Amniotic Fluid Soluble Myeloid Differentiation‐2 (sMD‐2) as Regulator of Intra‐amniotic Inflammation in Infection‐induced Preterm Birth. American Journal Of Reproductive Immunology 2015, 73: 507-521. PMID: 25605324, PMCID: PMC4430418, DOI: 10.1111/aji.12362.Peer-Reviewed Original ResearchConceptsMyeloid differentiation 2Preterm birthSMD-2Fetal membranesInflammation-induced preterm birthHuman AFIntra-amniotic inflammatory responseInfection-induced preterm birthIntra-amniotic inflammationIL-6 levelsNormal pregnancy outcomeDifferentiation 2MD-2 mRNATime-dependent fashionPregnancy outcomesImmunohistochemistry findingsTLR4 ligandInflammatory cytokinesInflammatory responseHost responseMRNA expressionLevel of expressionWestern blottingHistological localizationAF samples422: Evidence for the participation of neutrophil gelatinase-associated lipocalin (NGAL)/matrix metalloproteinase-9 (MMP-9) complex in the amniotic fluid inflammatory response to infection
Rood K, Millen K, Tabbah S, Bahtiyar M, Thung S, Summerfield T, Zhao G, Ackerman W, Shellhaas C, Samuels P, Buhimschi I, Buhimschi C. 422: Evidence for the participation of neutrophil gelatinase-associated lipocalin (NGAL)/matrix metalloproteinase-9 (MMP-9) complex in the amniotic fluid inflammatory response to infection. American Journal Of Obstetrics And Gynecology 2015, 212: s219. DOI: 10.1016/j.ajog.2014.10.468.Peer-Reviewed Original Research
2013
733: Mixed bacteria generate a differential intra-amniotic inflammatory response compared to infections with a single microbial species
Dulay A, Buhimschi C, Shook L, Zhao G, Bahtiyar M, Pettker C, Sfakianaki A, Lipkind H, Abdel-Razeq S, Buhimschi I. 733: Mixed bacteria generate a differential intra-amniotic inflammatory response compared to infections with a single microbial species. American Journal Of Obstetrics And Gynecology 2013, 208: s309. DOI: 10.1016/j.ajog.2012.10.071.Peer-Reviewed Original Research
2012
51: Evidence for the presence of super-interleukin-6 (superIL-6) trans-signaling complex in amniotic fluid (AF) and its participation in the intraamniotic inflammatory response to infection
Abdel-Razeq S, Buhimschi I, Trotta K, Zhao G, Bahtiyar M, Pettker C, Buhimschi C. 51: Evidence for the presence of super-interleukin-6 (superIL-6) trans-signaling complex in amniotic fluid (AF) and its participation in the intraamniotic inflammatory response to infection. American Journal Of Obstetrics And Gynecology 2012, 206: s32-s33. DOI: 10.1016/j.ajog.2011.10.077.Peer-Reviewed Original Research
2008
449: Amniotic fluid (AF) soluble toll-like receptor (TLR)-2 has functional ability to modulate the intensity of an intra-amniotic innate inflammatory response elicited by gram positive bacteria
Dulay A, Zhao G, Lee S, Abdel-Razeq S, Bahtiyar M, Pettker C, Buhimschi C, Buhimschi I. 449: Amniotic fluid (AF) soluble toll-like receptor (TLR)-2 has functional ability to modulate the intensity of an intra-amniotic innate inflammatory response elicited by gram positive bacteria. American Journal Of Obstetrics And Gynecology 2008, 199: s134. DOI: 10.1016/j.ajog.2008.09.478.Peer-Reviewed Original Research
2005
Evidence for participation of rage (receptor for advanced glycation end products), soluble rage (sRAGE) and S100A12 proteins, in control of the inflammatory response of amniotic cavity during pregnancy
Buhimschi I, Zhao G, Pettker C, Bahtiyar M, Magloire L, Buhimschi C. Evidence for participation of rage (receptor for advanced glycation end products), soluble rage (sRAGE) and S100A12 proteins, in control of the inflammatory response of amniotic cavity during pregnancy. American Journal Of Obstetrics And Gynecology 2005, 193: s9. DOI: 10.1016/j.ajog.2005.10.018.Peer-Reviewed Original Research