2023
ASAM Clinical Considerations: Buprenorphine Treatment of Opioid Use Disorder for Individuals Using High-potency Synthetic Opioids
Weimer M, Herring A, Kawasaki S, Meyer M, Kleykamp B, Ramsey K. ASAM Clinical Considerations: Buprenorphine Treatment of Opioid Use Disorder for Individuals Using High-potency Synthetic Opioids. Journal Of Addiction Medicine 2023, 17: 632-639. PMID: 37934520, DOI: 10.1097/adm.0000000000001202.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHigh potency synthetic opioidsOpioid use disorderBuprenorphine initiationBuprenorphine treatmentTreatment needsUse disordersClinical considerationsExpert consensusSynthetic opioidsTreatment of OUDProspective researchOpioid agonist treatmentLong-term treatmentDrug supplyPatients' treatment needsOpioid withdrawalBuprenorphine doseOUD treatmentAgonist treatmentDosing frequencyClinical questionsFrontline cliniciansClinical practiceTreatment settingsIndividualized strategiesLow-dose Initiation of Buprenorphine in Hospitalized Patients Using Buccal Buprenorphine: A Case Series
Adams K, Cohen S, Guerra M, Weimer M. Low-dose Initiation of Buprenorphine in Hospitalized Patients Using Buccal Buprenorphine: A Case Series. Journal Of Addiction Medicine 2023, 17: 474-476. PMID: 37579114, DOI: 10.1097/adm.0000000000001146.Peer-Reviewed Original ResearchConceptsOpioid use disorderBuprenorphine initiationSublingual buprenorphineChronic painBuccal buprenorphineCase seriesClinical Opiate Withdrawal Scale (COWS) scoresAddiction medicine serviceLow dose initiationSevere opioid withdrawalHistory of heroinOutpatient opioidsOpioid withdrawalAcute painFentanyl useHospitalized patientsMedian lengthPrescription refillsMedian numberModerate withdrawalInitiation strategiesBuprenorphineMedicine servicePatientsUse disordersPrecipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report
Christian N, Butner J, Evarts M, Weimer M. Precipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report. Journal Of Addiction Medicine 2023, 17: 488-490. PMID: 37579118, DOI: 10.1097/adm.0000000000001151.Peer-Reviewed Case Reports and Technical NotesConceptsClinical Opiate Withdrawal Scale (COWS) scoresOpioid use disorderKetamine infusionOpioid withdrawalCase reportUse disordersScale scoreSevere opioid use disorderFull opioid agonistsHours of admissionEmergency department settingFirst case reportInpatient hospital settingLife-saving medicationsReceptor-mediated signalingLack of evidenceMale patientsFentanyl useOpioid agonistsEmergency departmentComplete resolutionDepartment settingClinical dilemmaAppropriate treatmentHospital setting
2022
Management of opioid use disorder and associated conditions among hospitalized adults: A Consensus Statement from the Society of Hospital Medicine
Calcaterra SL, Martin M, Bottner R, Englander H, Weinstein Z, Weimer MB, Lambert E, Herzig SJ. Management of opioid use disorder and associated conditions among hospitalized adults: A Consensus Statement from the Society of Hospital Medicine. Journal Of Hospital Medicine 2022, 17: 744-756. PMID: 35880813, PMCID: PMC9474708, DOI: 10.1002/jhm.12893.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderConsensus statementHospitalized adultsOpioid withdrawalUse disordersTreatment of OUDDraft statementManagement of OUDHospital medicineAcute pain managementNumber of hospitalizationsHospital-based cliniciansFinal consensus statementOpioid-related overdoseHospital dischargeOpioid usePain managementWorking GroupCare transitionsInpatient settingObservational studyExpert consensusGuidance statementsPatientsSystematic reviewManagement of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines
Calcaterra SL, Bottner R, Martin M, Englander H, Weinstein ZM, Weimer MB, Lambert E, Ronan MV, Huerta S, Zaman T, Ullal M, Peterkin AF, Torres‐Lockhart K, Buresh M, O'Brien MT, Snyder H, Herzig SJ. Management of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines. Journal Of Hospital Medicine 2022, 17: 679-692. PMID: 35880821, PMCID: PMC9474657, DOI: 10.1002/jhm.12908.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid overdose preventionOpioid withdrawalOpioid useOUD treatmentOverdose preventionShort-acting opioid analgesicsOpioid use disorder managementAcute pain managementUse of methadoneOpioid use disorderEvaluation II (AGREE II) instrumentAppraisal of GuidelinesOpioid withdrawal managementUse of multimodalOpioid overdose reversalMethadone initiationNonopioid therapyHospitalized adultsBuprenorphine treatmentOpioid analgesicsPain managementTreatment guidelinesDiagnostic Statistical ManualOvid MEDLINEEdition criteriaClinical Management of Opioid Withdrawal
Torres‐Lockhart K, Lu TY, Weimer MB, Stein MR, Cunningham CO. Clinical Management of Opioid Withdrawal. Addiction 2022, 117: 2540-2550. PMID: 35112746, DOI: 10.1111/add.15818.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderOpioid withdrawal managementOpioid withdrawalClinical managementWithdrawal managementLong-term treatmentAppropriate clinical managementPatient-centered approachRelapse prevention strategiesHarm reduction strategiesHigh-risk timeOUD treatmentAppropriate diagnosisOpioid overdoseUse disordersPrevention strategiesTreatment settingsNarrative reviewWithdrawalTreatmentComplex casesManagementRelapsePatientsOverdose
2021
Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach
Cohen SM, Weimer MB, Levander XA, Peckham AM, Tetrault JM, Morford KL. Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach. Journal Of Addiction Medicine 2021, 16: 399-406. PMID: 34954746, DOI: 10.1097/adm.0000000000000945.Peer-Reviewed Original ResearchConceptsLow dose initiationFull opioid agonistsDose initiationOpioid withdrawal symptomsOpioid agonistsBuprenorphine doseWithdrawal symptomsHigh potency synthetic opioidsOpioid use disorderAppropriate clinical situationsMu-opioid receptorsBuprenorphine initiationOpioid withdrawalStarting doseOutpatient settingCare coordinationDose changesOverdose deathsCurrent evidenceUse disordersBuprenorphineTherapeutic levelsClinical situationsSynthetic opioidsNarrative review
2020
Hospital-based Buprenorphine Micro-dose Initiation
Weimer MB, Guerra M, Morrow G, Adams K. Hospital-based Buprenorphine Micro-dose Initiation. Journal Of Addiction Medicine 2020, 15: 255-257. PMID: 32960820, DOI: 10.1097/adm.0000000000000745.Peer-Reviewed Case Reports and Technical Notes
2019
Treatment of Opioid Use Disorder in the Acute Hospital Setting: a Critical Review of the Literature (2014–2019)
Weimer M, Morford K, Donroe J. Treatment of Opioid Use Disorder in the Acute Hospital Setting: a Critical Review of the Literature (2014–2019). Current Addiction Reports 2019, 6: 339-354. DOI: 10.1007/s40429-019-00267-x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsOpioid use disorderAddiction medicine consult serviceHospitalized patientsUse disordersInitiation of MOUDPurpose of ReviewPatientsConcomitant medical conditionsAcute hospital settingHealth care utilizationIntravenous opioid useTreatment of patientsAcute care hospitalsHealth care outcomesHospital initiationRecent FindingsManagementInfectious complicationsOpioid withdrawalOpioid useCare hospitalCare utilizationOutpatient settingPatient outcomesConsult serviceHospital careCare model