Featured Publications
Keeping an eye on circadian time in clinical research and medicine
Klerman E, Brager A, Carskadon M, Depner C, Foster R, Goel N, Harrington M, Holloway P, Knauert M, LeBourgeois M, Lipton J, Merrow M, Montagnese S, Ning M, Ray D, Scheer F, Shea S, Skene D, Spies C, Staels B, St‐Onge M, Tiedt S, Zee P, Burgess H. Keeping an eye on circadian time in clinical research and medicine. Clinical And Translational Medicine 2022, 12: e1131. PMID: 36567263, PMCID: PMC9790849, DOI: 10.1002/ctm2.1131.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Enhancing cosinor analysis of circadian phase markers using the gamma distribution
Doyle MM, Murphy TE, Miner B, Pisani MA, Lusczek ER, Knauert MP. Enhancing cosinor analysis of circadian phase markers using the gamma distribution. Sleep Medicine 2022, 92: 1-3. PMID: 35306404, PMCID: PMC9356385, DOI: 10.1016/j.sleep.2022.01.015.Peer-Reviewed Original Research
2021
A SAS macro for modelling periodic data using cosinor analysis
Doyle MM, Murphy TE, Pisani MA, Yaggi HK, Jeon S, Redeker NS, Knauert MP. A SAS macro for modelling periodic data using cosinor analysis. Computer Methods And Programs In Biomedicine 2021, 209: 106292. PMID: 34380075, PMCID: PMC8435001, DOI: 10.1016/j.cmpb.2021.106292.Peer-Reviewed Original Research
2019
Circadian Biology and Its Importance to Intensive Care Unit Care and Outcomes
Gao C, Knauert M. Circadian Biology and Its Importance to Intensive Care Unit Care and Outcomes. Seminars In Respiratory And Critical Care Medicine 2019, 40: 629-637. PMID: 31826263, DOI: 10.1055/s-0039-1698394.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsCircadian RhythmCritical CareCritical IllnessHumansIntensive Care UnitsSleepSleep Wake DisordersConceptsIll patientsIntensive care unit careIntensive care unit practiceCircadian rhythmCurrent ICU practiceLow-risk interventionNumerous adverse outcomesUnit careCritical illnessImmune compromiseCardiovascular instabilityMetabolic derangementsAdverse outcomesICU practiceUnit practicesSleep disruptionCare improvementPatientsOutcomesSleepRhythmBright lightDaysCircadian biologyDelirium
2018
Non-circadian signals in the intensive care unit: Point prevalence morning, noon and night
Altman MT, Pulaski C, Mburu F, Pisani MA, Knauert MP. Non-circadian signals in the intensive care unit: Point prevalence morning, noon and night. Heart & Lung 2018, 47: 610-615. PMID: 30143362, PMCID: PMC6234066, DOI: 10.1016/j.hrtlng.2018.07.011.Peer-Reviewed Original ResearchConceptsSleep promotion interventionsIntensive care unitICU patient roomsQuality improvement initiativesCare unitSleep disturbancesObservational studyICU roomAbnormal lightPatient roomsSound exposureImprovement initiativesDoor curtainsInterventionPrevalenceEnvironmental factorsBright lightRoom doorICUFactors
2015
Sleep Loss and Circadian Rhythm Disruption in the Intensive Care Unit
Knauert MP, Haspel JA, Pisani MA. Sleep Loss and Circadian Rhythm Disruption in the Intensive Care Unit. Clinics In Chest Medicine 2015, 36: 419-429. PMID: 26304279, DOI: 10.1016/j.ccm.2015.05.008.BooksMeSH KeywordsCircadian RhythmCritical IllnessDeliriumHumansIntensive Care UnitsSleepSleep DeprivationConceptsCritical illnessSleep disruptionAppropriate administrative supportIntensive care unit environmentIntensive care unitCircadian rhythm disruptionDelirium reductionIll patientsCare unitPharmacologic interventionsSleep disturbancesRhythm disruptionCare deliveryMultidisciplinary strategyUnit environmentSleep lossIllnessDisruptionPatientsEffective strategySleepEnvironmental factors