2024
Adding Insult to Injury Sleep Deficiency in Hospitalized Patients
Mansour W, Knauert M. Adding Insult to Injury Sleep Deficiency in Hospitalized Patients. Sleep Medicine Clinics 2024, 19: 607-623. PMID: 39455181, DOI: 10.1016/j.jsmc.2024.07.008.Peer-Reviewed Original ResearchConceptsHospital settingSleep promotion protocolsSleep deficiencyHospitalized patientsNegative health effectsObjective sleep measuresSleep measurement techniquesHospital outcomesMedical conditionsEffects of sleep deficiencyStudy protocolIllness severitySleep promotionHospital environmentImpact multiple organ systemsMultiple organ systemsHospitalTreatment-related effectsSleep measuresContributing factorsPromotion protocolOrgan systemsOutcomesPatientsSleep
2022
Sleep Deficiency and Health
Knauert MP. Sleep Deficiency and Health. Clinics In Chest Medicine 2022, 43: xiii-xiv. PMID: 35659032, DOI: 10.1016/j.ccm.2022.02.014.Peer-Reviewed Original Research
2019
Circadian Biology and Its Importance to Intensive Care Unit Care and Outcomes
Gao C, Knauert M. Circadian Biology and Its Importance to Intensive Care Unit Care and Outcomes. Seminars In Respiratory And Critical Care Medicine 2019, 40: 629-637. PMID: 31826263, DOI: 10.1055/s-0039-1698394.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsCircadian RhythmCritical CareCritical IllnessHumansIntensive Care UnitsSleepSleep Wake DisordersConceptsIll patientsIntensive care unit careIntensive care unit practiceCircadian rhythmCurrent ICU practiceLow-risk interventionNumerous adverse outcomesUnit careCritical illnessImmune compromiseCardiovascular instabilityMetabolic derangementsAdverse outcomesICU practiceUnit practicesSleep disruptionCare improvementPatientsOutcomesSleepRhythmBright lightDaysCircadian biologyDeliriumPilot study: an intensive care unit sleep promotion protocol
Knauert MP, Pisani M, Redeker N, Murphy T, Araujo K, Jeon S, Yaggi H. Pilot study: an intensive care unit sleep promotion protocol. BMJ Open Respiratory Research 2019, 6: e000411. PMID: 31258916, PMCID: PMC6561389, DOI: 10.1136/bmjresp-2019-000411.Peer-Reviewed Original ResearchConceptsPromotion protocolProtocol armUsual careSleep protocolICU sleepProtocol patientsIll patientsPrimary outcomeSleep disruptionBedside careRoom entryPatientsRoom activitiesSleep opportunityCareLength of timeProtocol effectMean ARoom disturbancesGeneralised linear modelArmTime blocksEquivalent levelsRoom entranceActivity
2018
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium
Knauert MP, Gilmore EJ, Murphy TE, Yaggi HK, Van Ness PH, Han L, Hirsch LJ, Pisani MA. Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. Journal Of Critical Care 2018, 48: 124-129. PMID: 30179762, PMCID: PMC6226351, DOI: 10.1016/j.jcrc.2018.08.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCritical CareCritical IllnessDeliriumElectroencephalographyFemaleHumansMaleMiddle AgedRetrospective StudiesSleep StagesSleep Wake DisordersConceptsICU patientsIll patientsOdds ratioHigher oddsSleep spindlesIntensive care unit outcomesGrade of encephalopathySignificant sleep disruptionWorse ICU outcomeMedical ICU patientsAcute brain injuryObservational cohort studySedative-hypnotic useImportant prognostic valueLength of stayStage N2 sleepK-complexesCohort studyCritical illnessHospital dischargeRankin ScaleICU outcomesPrognostic valueSevere gradesMedical recordsNon-circadian signals in the intensive care unit: Point prevalence morning, noon and night
Altman MT, Pulaski C, Mburu F, Pisani MA, Knauert MP. Non-circadian signals in the intensive care unit: Point prevalence morning, noon and night. Heart & Lung 2018, 47: 610-615. PMID: 30143362, PMCID: PMC6234066, DOI: 10.1016/j.hrtlng.2018.07.011.Peer-Reviewed Original ResearchMeSH KeywordsCircadian RhythmCritical CareHumansIntensive Care UnitsLightNoiseRespiration, ArtificialSleepSleep Wake DisordersSurveys and QuestionnairesTime FactorsConceptsSleep promotion interventionsIntensive care unitICU patient roomsQuality improvement initiativesCare unitSleep disturbancesObservational studyICU roomAbnormal lightPatient roomsSound exposureImprovement initiativesDoor curtainsInterventionPrevalenceEnvironmental factorsBright lightRoom doorICUFactors
2017
Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review
Altman MT, Knauert MP, Pisani MA. Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review. Annals Of The American Thoracic Society 2017, 14: 1457-1468. PMID: 28644698, PMCID: PMC5711402, DOI: 10.1513/annalsats.201702-148sr.BooksConceptsCritical illnessHospital dischargeSleep disturbancesRisk factorsSystematic reviewIntensive care unit admissionCare unit admissionIll adult patientsTime pointsCritical illness survivorsObjective sleep parametersQuestionnaire studyUnit admissionAdult patientsHospital factorsIll patientsPrimary outcomePrehospital factorsImpaired qualityObjective measurement toolsPsychological comorbiditiesAbnormal sleepMultiple time pointsPolysomnography studiesPoor sleep
2014
Sleep and Sleep Disordered Breathing in Hospitalized Patients
Knauert MP, Malik V, Kamdar BB. Sleep and Sleep Disordered Breathing in Hospitalized Patients. Seminars In Respiratory And Critical Care Medicine 2014, 35: 582-592. PMID: 25353103, DOI: 10.1055/s-0034-1390080.BooksConceptsHospitalized patientsPoor sleep qualityPatient care activitiesInpatient deliriumAcute illnessPatients' sleepAdverse outcomesModifiable factorsPoor sleepBreathing increasesHospital settingSleep qualityPatientsMetabolic consequencesMultidisciplinary teamEarly identificationCare activitiesSleep deprivationSleepBreathingCurrent knowledgeFundamental physiological processesPhysiological processesDeliriumMedications