2014
Sleep in Patients with Restrictive Lung Disease
Won CH, Kryger M. Sleep in Patients with Restrictive Lung Disease. Clinics In Chest Medicine 2014, 35: 505-512. PMID: 25156766, DOI: 10.1016/j.ccm.2014.06.006.ChaptersConceptsRestrictive lung diseaseLung diseaseObesity hypoventilation syndromeInterstitial lung diseasePathophysiology of sleepImpact of treatmentOverall prognosisVentilatory defectHypoventilation syndromeImpaired ventilationDaytime fatigueSleep disruptionRelated symptomsSleep disordersSleep qualityDiffusion impairmentNeuromuscular diseaseDiseasePatientsPathophysiologySleepHypoxemiaHypercarbiaPrognosisDysfunction
2008
Assessment and Management of Patients with Obesity Hypoventilation Syndrome
Mokhlesi B, Kryger MH, Grunstein RR. Assessment and Management of Patients with Obesity Hypoventilation Syndrome. Annals Of The American Thoracic Society 2008, 5: 218-225. PMID: 18250215, PMCID: PMC2645254, DOI: 10.1513/pats.200708-122mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObesity hypoventilation syndromeSleep-disordered breathingHypoventilation syndromeManagement of patientsAvailable treatment modalitiesRelated health care expendituresSerious cardiovascular diseaseHealth care expensesHealth care expendituresDaytime hypercapniaEucapnic patientsSignificant lungClinical characteristicsObese patientsSignificant morbidityEarly mortalityTreatment modalitiesEarly recognitionExtreme obesityCardiovascular diseaseHigh burdenEffective treatmentHigh riskHigh indexClinical practice
1990
Sleep in Postpolio Syndrome
Steljes D, Kryger M, Kirk B, Millar T. Sleep in Postpolio Syndrome. CHEST Journal 1990, 98: 133-140. PMID: 2361379, DOI: 10.1378/chest.98.1.133.Peer-Reviewed Original ResearchConceptsNasal mask ventilationPost-polio patientsGroup 1 patientsNasal CPAPPoor sleep qualityMask ventilationMixed apneaSleep qualityHypoventilation syndromeRespiratory complaintsPercentage stage 1 sleepRapid eye movement (REM) sleepNasal mechanical ventilationNight-time polysomnographyPost-polio symptomsSignificant O2 desaturationGroup 2 patientsRespiratory muscle weaknessNumber of arousalsEye movement sleepImproved sleep qualityPost-polio syndromeStage 1 sleepTotal sleep timeSlow-wave sleep