2016
Radiosensitization effect of Huaier on breast cancer cells
DING X, YANG Q, KONG X, HAFFTY BG, GAO S, MORAN MS. Radiosensitization effect of Huaier on breast cancer cells. Oncology Reports 2016, 35: 2843-2850. PMID: 26935024, DOI: 10.3892/or.2016.4630.Peer-Reviewed Original ResearchConceptsBreast cancer cellsDNA repairTraditional Chinese medicineCell cycleBreast cancerCancer cellsDNA repair pathwaysCell cycle-regulating proteinsHomologous recombination pathwayRadiosensitization effectMulti-biological functionsCell cycle phasesColony formation assaysMDA-MB-468 cellsΓ-H2AX fociCell divisionRepair pathwaysG0/G1Treatment strategiesMicroarray assayRecombination pathwayFormation assaysHuaierCancer treatmentWestern blotting
2011
Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial–mesenchymal transition
Zhang X, Li X, Zhang N, Yang Q, Moran MS. Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial–mesenchymal transition. Biochemical And Biophysical Research Communications 2011, 412: 188-192. PMID: 21810413, DOI: 10.1016/j.bbrc.2011.07.074.Peer-Reviewed Original ResearchConceptsEpithelial-mesenchymal transitionBreast cancer cellsMCF-7 cellsCancer cellsMCF-7 breast cancer cellsEpithelial differentiation markersBreast cancerEMT markersLow doseMesenchymal markersTherapeutic effectivenessTranswell assaysMolecular alterationsLow dosesMesenchymal transitionRT-PCRCell invasionEnhanced migrationDifferentiation markersLDIRInvasivenessMarkersCellsPhenotypic changesInvasion
2010
Riluzole Increases Ionizing Radiation Related Cellular Toxicity in Metabotropic Glutamate Receptor 1 Positive Human Breast Cancer Cells
Ahlawat S, Khan A, Goyal S, Schiff D, Wu H, Moran M, Haffty B. Riluzole Increases Ionizing Radiation Related Cellular Toxicity in Metabotropic Glutamate Receptor 1 Positive Human Breast Cancer Cells. International Journal Of Radiation Oncology • Biology • Physics 2010, 78: s160. DOI: 10.1016/j.ijrobp.2010.07.394.Peer-Reviewed Original Research