2006
The Implications of Mental Stress for Cardiovascular Disease
Graeber B, Soufer A, Burg M, Soufer R. The Implications of Mental Stress for Cardiovascular Disease. Contemporary Cardiology 2006, 197-215. DOI: 10.1007/978-1-59745-096-6_11.Peer-Reviewed Original Research
2001
Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation
Jain D, Joska T, Lee F, Burg M, Lampert R, Zaret B. Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation. Journal Of Nuclear Cardiology 2001, 8: 347-355. PMID: 11391305, DOI: 10.1067/mnc.2001.113517.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseSystolic blood pressureLV ejection fractionLV dysfunctionRate-pressure productBlood pressureAnger recallMS taskHeart rate variabilityAutonomic activationLVEF responseArtery diseaseMental stressSympathetic activationHeart rateSymptomatic coronary artery diseaseRate variabilityAbnormal LVEF responseVentricular function responseChronic stable anginaExercise-induced ischemiaLeft ventricular dysfunctionAdverse prognostic signLF/HFCardiac medications7.44 Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease
Arrighi J, Burg M, Cohen I, Soufer R. 7.44 Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease. Journal Of Nuclear Cardiology 2001, 8: s51. DOI: 10.1016/s1071-3581(01)80621-8.Peer-Reviewed Original Research
2000
Myocardial blood-flow response during mental stress in patients with coronary artery disease
Arrighi J, Burg M, Cohen I, Kao A, Pfau S, Caulin-Glaser T, Zaret B, Soufer R. Myocardial blood-flow response during mental stress in patients with coronary artery disease. The Lancet 2000, 356: 310-311. PMID: 11071190, DOI: 10.1016/s0140-6736(00)02510-1.Peer-Reviewed Original ResearchDestabilizing Effects of Mental Stress on Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators
Lampert R, Jain D, Burg M, Batsford W, McPherson C. Destabilizing Effects of Mental Stress on Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators. Circulation 2000, 101: 158-164. PMID: 10637203, DOI: 10.1161/01.cir.101.2.158.Peer-Reviewed Original ResearchConceptsEvidence of ischemiaVentricular tachycardiaVentricular arrhythmiasMental stressAntitachycardia pacingSudden deathSudden cardiac death increasesInduced ventricular tachycardiaEase of inductionVT cycle lengthLethal ventricular arrhythmiasImplantable cardioverter defibrillatorUnderwent repeat testingCardioverter defibrillatorPatientsRepeat testingArrhythmiasDeath increasesMental arousalPsychological stressSympathetic arousalIschemiaCycle lengthStress altersPacing
1999
Myocardial blood flow decreases during mental stress independent of vasodilator capacity/severity of CAD
Arrighi J, Burg M, Cohen I, Bremner D, Zaret B, Soufer R. Myocardial blood flow decreases during mental stress independent of vasodilator capacity/severity of CAD. Journal Of Nuclear Cardiology 1999, 6: s12. DOI: 10.1016/s1071-3581(99)90162-9.Peer-Reviewed Original Research
1998
Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease
Soufer R, Bremner J, Arrighi J, Cohen I, Zaret B, Burg M, Goldman-Rakic P. Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 6454-6459. PMID: 9600987, PMCID: PMC27794, DOI: 10.1073/pnas.95.11.6454.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseVisual association cortexSuperior frontal gyrusRight visual association cortexCAD patientsHealthy subjectsPositron emission tomographyMental stressAssociation cortexFrontal gyrusArtery diseaseMyocardial ischemiaAnterior cingulateCentral nervous system effectsCAD patient groupCerebral cortical responsePainless myocardial ischemiaNervous system effectsLeft parietal cortexInferior parietal lobuleMiddle temporal gyrusPatient groupSerial subtraction taskRight thalamusInferior frontal gyrusEffects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease
Jain D, Shaker M, Burg M, Wackers F, Soufer R, Zaret B. Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1314-1322. PMID: 9581726, DOI: 10.1016/s0735-1097(98)00092-8.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionPeripheral vascular resistanceCoronary artery diseaseRate-pressure productStress-induced fallSystolic blood pressureArtery diseaseBlood pressureCardiac outputHeart rateMental stressGroup IHemodynamic variablesAnger recallGroup IIMental stressorsEnd-systolic ventricular elastanceMental stress-induced changesSemisupine bicycle exerciseGroup II patientsComparable increaseDiastolic blood pressureVentricular ejection fractionExercise-induced changesVascular resistance
1995
Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris
Jain D, Burg M, Soufer R, Zaret B. Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris. The American Journal Of Cardiology 1995, 76: 31-35. PMID: 7793399, DOI: 10.1016/s0002-9149(99)80796-6.Peer-Reviewed Original ResearchConceptsStable angina pectorisTransient LV dysfunctionAdverse cardiac eventsCardiac eventsLV dysfunctionAngina pectorisMental stressAbnormal cardiovascular reactivityHigher cardiac eventsCohort of patientsCoronary artery diseaseGroup of patientsVentricular function monitoringMental arithmeticVentricular dysfunctionAdverse eventsBaseline characteristicsBeta blockersContinuous ambulatoryArtery diseaseRisk stratificationPrognostic implicationsStress perfusionFunction monitoringHeart rateEjection fraction fall during mental stress in coronary artery disease: Is it due to peripheral effects or contractile dysfunction?
Shaker S, Jain D, Burg M, Wackers F, Soufer R, Zaret B. Ejection fraction fall during mental stress in coronary artery disease: Is it due to peripheral effects or contractile dysfunction? Journal Of Nuclear Cardiology 1995, 2: s27. DOI: 10.1016/s1071-3581(05)80195-3.Peer-Reviewed Original ResearchPrognostic value of mental stress induced silent left ventricular dysfunction in coronary artery disease
Jain D, Burg M, Soufer R, Zaret B. Prognostic value of mental stress induced silent left ventricular dysfunction in coronary artery disease. Journal Of Nuclear Cardiology 1995, 2: s91. DOI: 10.1016/s1071-3581(05)80449-0.Peer-Reviewed Original ResearchMental stress induced left ventricular dysfunction: Role of changes in arterial and ventricular elastance and ventriculo-arterial coupling
Jain D, Shaker S, Burg M, Wackers F, Zaret B. Mental stress induced left ventricular dysfunction: Role of changes in arterial and ventricular elastance and ventriculo-arterial coupling. Journal Of Nuclear Cardiology 1995, 2: s124. DOI: 10.1016/s1071-3581(05)80577-x.Peer-Reviewed Original Research
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1991
Silent left ventricular dysfunction during routine structured interview and induced mental stress in stable coronary patients: Impact of type a behavior
Jain D, Burg M, Soufer R, Kerns R, Zaret B. Silent left ventricular dysfunction during routine structured interview and induced mental stress in stable coronary patients: Impact of type a behavior. Journal Of The American College Of Cardiology 1991, 17: a90. DOI: 10.1016/0735-1097(91)91326-a.Peer-Reviewed Original Research