2020
Effects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial
Black D, Minkin M, Graham S, Bernick B, Mirkin S. Effects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial. Menopause The Journal Of The North American Menopause Society 2020, 28: 32-39. PMID: 32932401, PMCID: PMC7769186, DOI: 10.1097/gme.0000000000001659.Peer-Reviewed Original ResearchConceptsE2/P4Diastolic blood pressureSystolic blood pressureBlood pressurePostmenopausal womenREPLENISH trialMonth 12Treatment-emergent adverse eventsWeight gainTwelve-month useHealthy postmenopausal womenSevere vasomotor symptomsBody mass indexAdverse eventsVasomotor symptomsMass indexEfficacy profileWomenBaselineHypertensionPlaceboUterusTrialsImportant changesPrevious findings
2011
Suspected black cohosh hepatotoxicity
Naser B, Schnitker J, Minkin M, de Arriba S, Nolte K, Osmers R. Suspected black cohosh hepatotoxicity. Menopause The Journal Of The North American Menopause Society 2011, 18: 366-375. PMID: 21228727, DOI: 10.1097/gme.0b013e3181fcb2a6.Peer-Reviewed Original ResearchConceptsIsopropanolic black cohosh extractClinical trialsPostmenopausal womenLiver functionAlanine aminotransferaseAspartate aminotransferaseBlack cohoshPopular herbal treatmentPlacebo-controlled studyMonths of treatmentLiver function valuesStandardized mean differenceBlack cohosh extractMenopausal symptomsHerbal treatmentHepatotoxicity casesMean differenceAdverse effectsAminotransferaseTrialsWomenNonsignificant effectDescriptive statisticsMonthsΓ-glutamyltranspeptidase