2023
Worry and Mindfulness Differentially Impact Symptom Burden Following Treatment Among Breast Cancer Survivors: Findings From a Randomized Crossover Trial
Renna M, Madison A, Peng J, Shrout M, Lustberg M, Ramaswamy B, Wesolowski R, VanDeusen J, Williams N, Sardesai S, Noonan A, Reinbolt R, Stover D, Cherian M, Malarkey W, Andridge R, Kiecolt-Glaser J. Worry and Mindfulness Differentially Impact Symptom Burden Following Treatment Among Breast Cancer Survivors: Findings From a Randomized Crossover Trial. Annals Of Behavioral Medicine 2023, 57: 888-898. PMID: 37335884, PMCID: PMC10498820, DOI: 10.1093/abm/kaad032.Peer-Reviewed Original ResearchConceptsEmotion regulationMemory problemsCognitive tasksBreast cancer survivorsEmotion regulation abilitiesAdaptive emotion regulationEmotion regulation skillsHigher subjective fatigueSubjective memory problemsCancer survivorsCognitive side effectsPain sensitivityRegulation skillsLow mindfulnessCognitive problemsMindfulness QuestionnaireRegulation abilitySubjective fatiguePhysical healthBreast cancer survivorshipCold pain sensitivityObjective ratingsConcentration problemsMindfulnessInflammatory responseConflicts hurt: social stress predicts elevated pain and sadness after mild inflammatory increases
Madison A, Renna M, Andridge R, Peng J, Shrout M, Sheridan J, Lustberg M, Ramaswamy B, Wesolowski R, Williams N, Noonan A, Reinbolt R, Stover D, Cherian M, Malarkey W, Kiecolt-Glaser J. Conflicts hurt: social stress predicts elevated pain and sadness after mild inflammatory increases. Pain 2023, 164: 1985-1994. PMID: 36943254, PMCID: PMC10440304, DOI: 10.1097/j.pain.0000000000002894.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsCancer survivorsChronic social stressPostmenopausal breast cancer survivorsInterleukin-1 receptor antagonistSocial stressEffects of inflammationAcute inflammatory responseSaline placeboChronic painElevated painMore painReceptor antagonistInterleukin-6Inflammatory responseHours postinjectionDepression riskPainInflammatory increasesNervous systemSeparate visitsNonsocial stressVaccine sequenceBehavioral covariatesInflammationDexamethasone to prevent everolimus-induced stomatitis (Alliance MIST Trial: A221701)
Ruddy K, Zahrieh D, He J, Waechter B, Holleran J, Lewis L, Chow S, Beumer J, Weiss M, Trikalinos N, Faller B, Lustberg M, Rugo H, Loprinzi C. Dexamethasone to prevent everolimus-induced stomatitis (Alliance MIST Trial: A221701). Seminars In Oncology 2023, 50: 7-10. PMID: 36693773, PMCID: PMC10247389, DOI: 10.1053/j.seminoncol.2023.01.001.Peer-Reviewed Original ResearchConceptsMTOR inhibitor-associated stomatitisDexamethasone mouthwashCoprimary endpointsTrough concentrationsExact testRandomized phase III trialEverolimus trough concentrationsPrior clinical researchPhase III trialsDose-limiting toxicityFisher's exact testMann-Whitney U testWilcoxon rank sum testRank sum testOral everolimusIII trialsOral stomatitisTreatment periodMouth rinseMTOR inhibitorsPoor enrollmentClinical researchEverolimusU testStomatitis
2021
Supportive Care: Low Cost, High Value.
Popescu RA, Roila F, Arends J, Metro G, Lustberg M. Supportive Care: Low Cost, High Value. American Society Of Clinical Oncology Educational Book 2021, 41: 1-11. PMID: 33830830, DOI: 10.1200/edbk_320041.Peer-Reviewed Original ResearchConceptsQuality of lifePhysical exerciseChemotherapy-induced peripheral neuropathyLarge phase III trialsElectronic patient-reported outcome measuresPatient-reported outcome measuresPersonalization of chemotherapySupportive care unitPhase III trialsSupportive care interventionsCancer-related fatigueMind-body interventionsNonpharmacologic strategiesScrambler therapyGastrointestinal dysmotilityIII trialsOverall survivalSupportive careTreatable causeMuscle trainingPeripheral neuropathyCare unitClinic appointmentsMetabolic derangementsRegular screening
2020
Worry and rumination in breast cancer patients: perseveration worsens self-rated health
Renna ME, Rosie Shrout M, Madison AA, Lustberg M, Povoski SP, Agnese DM, Reinbolt RE, Wesolowski R, Williams NO, Ramaswamy B, Sardesai SD, Noonan AM, VanDeusen JB, Malarkey WB, Kiecolt-Glaser JK. Worry and rumination in breast cancer patients: perseveration worsens self-rated health. Journal Of Behavioral Medicine 2020, 44: 253-259. PMID: 33135103, PMCID: PMC8272958, DOI: 10.1007/s10865-020-00192-9.Peer-Reviewed Original ResearchConceptsSelf-rated healthBreast cancer patientsBreast Cancer Prevention Trial Symptom ChecklistCancer-related distressBreast cancer symptomsPoor physical functioningPhysical functioningCancer patientsPhysical symptomsAdjuvant treatmentCancer symptomsGreater cancer-related distressHigher cancer-related distressGreater painLower self-rated healthBody mass indexQuality of lifePhysical comorbiditiesMass indexRAND-36Menopause statusCancer stageCancer trajectorySymptom ChecklistSymptoms