2021
Emerging Diagnostics for Transplant Infectious Diseases
Azar M, Gaston D, Malinis M. Emerging Diagnostics for Transplant Infectious Diseases. 2021, 1535-1576. DOI: 10.1007/978-3-030-25869-6_69.Peer-Reviewed Original ResearchTransplant infectious diseasesInfectious diseasesPolymerase chain reaction panelHematopoietic stem cell transplantationCommunity-acquired infectionsStem cell transplantationMultidrug-resistant organismsTest performance characteristicsTransplant patientsUncommon pathogenCell transplantationSerious infectionsPatient outcomesClinical impactDiagnostic modalitiesSolid organsMolecular testingClinical specimensPatientsDiseaseDiagnostic advantageInfectionResistance detectionDiagnostic methodsDiagnostic capabilitiesA retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients
Ringer M, Azmy V, Kaman K, Tang D, Cheung H, Azar MM, Price C, Malinis M. A retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients. Transplant Infectious Disease 2021, 23: e13556. PMID: 33378571, PMCID: PMC7883059, DOI: 10.1111/tid.13556.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedCase-Control StudiesCohort StudiesComorbidityCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeFemaleGlucocorticoidsGraft RejectionHeart TransplantationHospitalizationHumansImmunologic FactorsImmunosuppressive AgentsInterleukin-10Interleukin-6Kidney TransplantationLiver TransplantationMaleMiddle AgedReceptors, Interleukin-2Retrospective StudiesSARS-CoV-2Severity of Illness IndexTreatment OutcomeYoung AdultConceptsCytokine release syndromeBody mass indexNon-SOT patientsSOT groupSOT patientsRelease syndromeInterleukin-6COVID-19-related cytokine release syndromeSoluble interleukin-2 receptor levelsControl groupInterleukin-2 receptor levelsSolid organ transplant patientsSolid organ transplant recipientsImpact of immunomodulationInterleukin-10 levelsOrgan transplant recipientsOrgan transplant patientsCritical care needsMulti-center studyCoronavirus disease 2019COVID-19Interleukin levelsIndex hospitalizationTransplant patientsTransplant recipients
2020
Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region.
Nussbaum EZ, Patel KK, Assi R, Raad RA, Malinis M, Azar MM. Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region. Archives Of Pathology & Laboratory Medicine 2020, 145: 988-999. PMID: 33290524, DOI: 10.5858/arpa.2020-0271-oa.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBartonellaBiopsyCommunicable DiseasesConnecticutCytomegalovirusFemaleGranulomaHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedOrgan TransplantationPrevalenceRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTransplantation, HomologousTreatment OutcomeYoung AdultConceptsEpidemiologic risk factorsPresence of symptomsInfectious etiologyAsymptomatic patientsTransplant recipientsTissue granulomasClinicopathologic featuresRisk factorsAllogeneic hematopoietic stem cell transplant recipientsHematopoietic stem cell transplant recipientsStem cell transplant recipientsYale-New Haven HospitalCommon infectious etiologiesLarge transplant populationCell transplant recipientsSingle-center studyCryptogenic organizing pneumoniaNew Haven HospitalRoutine disease surveillancePaucity of literatureCytomegalovirus hepatitisPosttransplant specimensBiopsy indicationOrganizing pneumoniaTransplant patientsEmerging Diagnostics for Transplant Infectious Diseases
Azar M, Gaston D, Malinis M. Emerging Diagnostics for Transplant Infectious Diseases. 2020, 1-44. DOI: 10.1007/978-3-030-01751-4_69-1.Peer-Reviewed Original ResearchTransplant infectious diseasesInfectious diseasesPolymerase chain reaction panelHematopoietic stem cell transplantationCommunity-acquired infectionsStem cell transplantationMultidrug-resistant organismsTest performance characteristicsTransplant patientsUncommon pathogenCell transplantationSerious infectionsPatient outcomesClinical impactDiagnostic modalitiesSolid organsMolecular testingClinical specimensPatientsDiseaseDiagnostic advantageInfectionResistance detectionDiagnostic methodsDiagnostic capabilities