2024
Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children
Goodwin J, Kajubi R, Wang K, Li F, Wade M, Orukan F, Huang L, Whalen M, Aweeka F, Mwebaza N, Parikh S. Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children. Nature Communications 2024, 15: 3817. PMID: 38714692, PMCID: PMC11076639, DOI: 10.1038/s41467-024-48210-7.Peer-Reviewed Original ResearchConceptsDay 7 lumefantrine concentrationsArtemether-lumefantrine treatmentRing-stage parasitesEarly post-treatmentEarly post-treatment periodArtemether-lumefantrineArtemisinin resistanceDay regimenMulticlonal infectionsEfficacious therapyFollow-upRandomized trialsPersistent clonesTransmission settingsEffective treatmentPost-treatment periodRegimensAntimalarial studiesStandard diagnosticsStandard 3DaysPost-treatmentChildrenTreatmentTherapy
2016
Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda - Volume 22, Number 8—August 2016 - Emerging Infectious Diseases journal - CDC
Roh ME, Oyet C, Orikiriza P, Wade M, Kiwanuka GN, Mwanga-Amumpaire J, Parikh S, Boum Y. Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda - Volume 22, Number 8—August 2016 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2016, 22: 1494-1498. PMID: 27434741, PMCID: PMC4982177, DOI: 10.3201/eid2208.160619.Peer-Reviewed Original ResearchConceptsMicroscopy-positive samplesLow malaria transmission settingsInfectious Diseases journal - CDCAsymptomatic Plasmodium infectionsMalaria transmission settingsRapid diagnostic testsP. falciparum parasitesRoutine diagnostic testingP. ovale parasitesAsymptomatic childrenPlasmodium infectionPlasmodium malariaeP. malariaeTransmission settingsFalciparum parasitesDiagnostic testingDiagnostic testsMalariaeChildrenParasitesInfection