2003
Two Populations of Node Monocilia Initiate Left-Right Asymmetry in the Mouse
McGrath J, Somlo S, Makova S, Tian X, Brueckner M. Two Populations of Node Monocilia Initiate Left-Right Asymmetry in the Mouse. Cell 2003, 114: 61-73. PMID: 12859898, DOI: 10.1016/s0092-8674(03)00511-7.Peer-Reviewed Original Research
2002
Conserved function for embryonic nodal cilia
Essner JJ, Vogan KJ, Wagner MK, Tabin CJ, Yost HJ, Brueckner M. Conserved function for embryonic nodal cilia. Nature 2002, 418: 37-38. PMID: 12097899, DOI: 10.1038/418037a.Peer-Reviewed Original ResearchConceptsVertebrate body plan
1999
Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries
Supp D, Brueckner M, Kuehn M, Witte D, Lowe L, McGrath J, Corrales J, Potter S. Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries. Development 1999, 126: 5495-5504. PMID: 10556073, PMCID: PMC1797880, DOI: 10.1242/dev.126.23.5495.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAmino Acid SequenceAnimalsAxonemal DyneinsBinding SitesBody PatterningCatalytic DomainCiliaCloning, MolecularDyneinsFunctional LateralityGene Expression Regulation, DevelopmentalHeadMaleMiceMice, Inbred StrainsMolecular Sequence DataMutationNervous SystemSequence AnalysisSequence DeletionConceptsLeft-right dyneinLeft-right developmentLeft-right asymmetryEmbryonic day 8.0Microtubule-based motor proteinsAsymmetric expression patternLevel of sequenceComplete coding sequenceEmbryonic day 7.5Single amino acid differenceLeft-right specificationAmino acid differencesLeft-right axisLgl mutantsATP bindingConserved positionDay 8.0Inversus viscerum (iv) mouseCoding sequenceMotor proteinsDorsoventral axesExpression patternsGerm layersAcid differencesGenes