2023
Acquired Disorders of Hypomagnesemia
Rosner M, Ha N, Palmer B, Perazella M. Acquired Disorders of Hypomagnesemia. Mayo Clinic Proceedings 2023, 98: 581-596. PMID: 36872194, DOI: 10.1016/j.mayocp.2022.12.002.Peer-Reviewed Original ResearchConceptsReduced glomerular filtration rateBody storesBody magnesium storesGlomerular filtration rateSerum magnesium levelsTotal body storesDevelopment of symptomsIntravenous replacementOrgan dysfunctionMagnesium disordersRenal lossMagnesium replacementFiltration rateSevere casesMagnesium storesHypomagnesemiaClinical experienceClinical practiceMagnesium levelsAcquired disordersAmphotericin BMagnesium handlingOptimal managementMedicationsLaboratory assessment
2018
Drug-Induced Acute Kidney Injury
Luciano R, Perazella M. Drug-Induced Acute Kidney Injury. 2018, 145-163. DOI: 10.1007/978-1-4939-8628-6_9.Peer-Reviewed Original ResearchDrug-induced acute kidney injuryAcute kidney injuryKidney injuryAcute tubular injury/necrosisAcute interstitial nephritisFocal segmental glomerulosclerosisDrugs/substancesOsmotic nephropathyRisk patientsInterstitial nephritisKidney functionPrescribed medicationsSegmental glomerulosclerosisEarly identificationRenal compartmentsInjuryHarmful drugsTherapeutic agentsAdverse effectsCommon formDrugsMedicationsKidneyCommon problemDiagnostic agents35 Kidney Disease Caused by Therapeutic Agents
Perazella M, Shirali A. 35 Kidney Disease Caused by Therapeutic Agents. 2018, 334-344. DOI: 10.1016/b978-0-323-47794-9.00035-4.BooksKidney diseaseTherapeutic agentsDrug-induced renal toxicityProteinuria/nephrotic syndromeFrequent adverse consequencesChronic kidney diseaseChronic kidney injuryDrugs of abuseSubgroup of individualsDrug nephrotoxicityKidney injuryMost medicationsNephrotoxic drugsTubular dysfunctionNephrotic syndromeRenal toxicityDrug therapyRisk factorsTherapeutic medicationsRenal syndromeAppropriate careMedicationsNephrotoxicitySyndromeAdverse consequences
2016
Drug-Induced Hypertension in Chronic Kidney Disease
Vichot A, Perazella M. Drug-Induced Hypertension in Chronic Kidney Disease. 2016, 261-298. DOI: 10.1007/978-1-4939-6436-9_12.Peer-Reviewed Original ResearchChronic kidney diseaseCardiovascular complicationsKidney diseaseEnd-stage renal diseaseStrong risk factorHypertensive effectInflammatory syndromeBlood pressureRenal diseaseCounter medicationsMyocardial infarctionRisk factorsPhysiologic alterationsMood disordersHealthcare providersPatientsHypertensionDiseaseComplicationsMedicationsDrugsRiskPainInfarctionProviders
2015
New drug toxicities in the onco-nephrology world
Perazella MA, Izzedine H. New drug toxicities in the onco-nephrology world. Kidney International 2015, 87: 909-917. PMID: 25671763, DOI: 10.1038/ki.2015.30.Peer-Reviewed Original ResearchConceptsKidney injuryAnticancer medicationsAdverse renal consequencesAcute kidney injuryChronic kidney diseaseLevel of proteinuriaMore effective therapiesRenal consequencesElectrolyte disturbancesKidney diseaseNephrotoxic effectsNephrotoxic potentialRisk factorsEffective therapyNephrotoxic manifestationsDrug toxicityNew agentsOld drugsNephrology communityResistant cancersClinical arenaAvailable evidenceMedicationsPatientsInjury
2000
Drug-induced hyperkalemia: old culprits and new offenders
Perazella M. Drug-induced hyperkalemia: old culprits and new offenders. The American Journal Of Medicine 2000, 109: 307-314. PMID: 10996582, DOI: 10.1016/s0002-9343(00)00496-4.Peer-Reviewed Original ResearchConceptsDrug-induced hyperkalemiaRisk of hyperkalemiaRenal potassium excretionRenal impairmentPatient characteristicsPotassium excretionPotassium handlingPotassium loadPrescribed medicationsExcessive ingestionHyperkalemiaCounter drugsOld culpritsNutritional supplementsPotassium homeostasisMedicationsPatientsDrugsCellular uptakeInfusionAbnormalitiesExcretionPhysiciansImpairmentIngestion
1999
Crystal-induced acute renal failure
Perazella M. Crystal-induced acute renal failure. The American Journal Of Medicine 1999, 106: 459-465. PMID: 10225250, DOI: 10.1016/s0002-9343(99)00041-8.Peer-Reviewed Original ResearchConceptsAcute renal failureRenal insufficiencyRenal failureVolume repletionAppropriate drug dosingIntrarenal crystal depositionAcute renal insufficiencyIntravascular volume depletionAdditional risk factorsHigh urinary flowDialytic supportUrinary flowRisk factorsVolume depletionDrug dosingDrug dosesCrystal depositionIntratubular precipitationInsufficiencyUrineMedicationsRepletionFurther exposureFailureHuman urine
1998
Indinavir nephropathy in an AIDS patient with renal insufficiency and pyuria.
Perazella M, Kashgarian M, Cooney E. Indinavir nephropathy in an AIDS patient with renal insufficiency and pyuria. Clinical Nephrology 1998, 50: 194-6. PMID: 9776425.Peer-Reviewed Original ResearchConceptsRenal biopsy findingsRenal insufficiencyBiopsy findingsMild renal insufficiencyAcute renal failureIndinavir crystalsIndinavir therapyRenal failureAntiretroviral agentsUrinary obstructionAIDS patientsCellular castsPatientsPyuriaInsufficiencyRecent reportsSmall percentDiscontinuationNephropathyMedicationsSecond caseDiuresisNephrolithiasisIndinavirObstruction
1997
Hyperkalemia in the Elderly
Perazella M, Mahnensmith R. Hyperkalemia in the Elderly. Journal Of General Internal Medicine 1997, 12: 646-656. PMID: 9346463, PMCID: PMC1497179, DOI: 10.1046/j.1525-1497.1997.07128.x.Peer-Reviewed Original ResearchConceptsDevelopment of hyperkalemiaPotassium-altering medicationsAppropriate managementPrevention of hyperkalemiaHigh-risk medicationsManagement of hyperkalemiaCellular potassium uptakePlasma potassium concentrationPertinent review articlesCardiac complicationsElderly patientsPotassium handlingRenal functionSevere hyperkalemiaCertain medicationsElectrolyte disordersGeriatric patientsClinical manifestationsElderly subjectsMEDLINE searchHyperkalemiaMedicationsDisease processRenal disposalPotassium levelsBone marrow transplant nephropathy: a case report and review of the literature.
Cruz D, Perazella M, Mahnensmith R. Bone marrow transplant nephropathy: a case report and review of the literature. Journal Of The American Society Of Nephrology 1997, 8: 166-73. PMID: 9013462, DOI: 10.1681/asn.v81166.Peer-Reviewed Original ResearchConceptsBone marrow transplant nephropathyBone marrow transplantationRenal injuryTransplant nephropathyMarrow transplantationLate renal injuryEarly renal injuryHemolytic uremic syndromeVariety of causesNephrotoxic medicationsRenal failurePathologic featuresCase reportUremic syndromeLate effectsRadiation therapyRenal syndromeSyndromeNephropathySubsequent treatmentTransplantationInjuryMedicationsChemotherapyReview
1994
Electrolyte and acid-base disorders associated with AIDS
Perazella M, Brown E. Electrolyte and acid-base disorders associated with AIDS. Journal Of General Internal Medicine 1994, 9: 232-236. PMID: 8014731, DOI: 10.1007/bf02600132.Peer-Reviewed Original Research