Centrally administered galanin blocks morphine place preference in the mouse
Zachariou V, Parikh K, Picciotto M. Centrally administered galanin blocks morphine place preference in the mouse. Brain Research 1999, 831: 33-42. PMID: 10411981, DOI: 10.1016/s0006-8993(99)01476-6.Peer-Reviewed Original ResearchConceptsNucleus accumbensMorphine reinforcementLocus coeruleusSpinal cordPlace preferenceAcute naltrexone administrationGalanin binding sitesQuantitative receptor autoradiographyVentral tegmental areaMorphine place preferencePlace preference paradigmGalaninergic systemMorphine treatmentPeripheral administrationNaltrexone administrationReceptor autoradiographyGalanin bindingOpioid receptorsTegmental areaNeuroendocrine functionGalaninBrain areasDrug dependenceMorphineAversive propertiesModulation of morphine analgesia in αCGRP mutant mice
Salmon A, Damaj I, Sekine S, Picciotto M, Marubio L, Changeux J. Modulation of morphine analgesia in αCGRP mutant mice. Neuroreport 1999, 10: 849-854. PMID: 10208559, DOI: 10.1097/00001756-199903170-00033.Peer-Reviewed Original ResearchConceptsHot plate testMorphine analgesiaMutant miceTail-flick testPlate testWild-type miceMotor end platesPain pathwaysCGRP immunoreactivityMice lackFlick testMuscle synapsesAntinociceptive behaviorSpinal cordTail flickSpinal gangliaMiceAnalgesiaTargeted disruptionExon 5End platesMorphineGangliaCordImmunoreactivity